Teratological effects of 2,4-dinitrophenol, produced water' and naphthalene on embryos of the inland silverside Menidia beryllina

Middaugh, Douglas P.; Hemmer, MJ; Lores, EM

doi:10.3354/dao004053

Cited by 30 publications

(15 citation statements)

References 15 publications

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“…The loading and exposure procedures were similar to those described by Middaugh et al (1988). Borosilicate glass culture tubes 16 X 93 mm (window size l l x 55 mm) were used as exposure vessels.…”

Section: Methodsmentioning

confidence: 99%

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Hemmer¹,

Middaugh²,

Moore³

1990

Dis. Aquat. Org.

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Embryos of the inland silverside Menidia beryllina were exposed to the organophosphorus pesticide terbufos at 9 combinations of temperature (20, 25 and 30°C) and salinity (5, 12.5 and 20%.). Nominal exposure concentrations were 12.5, 25, 50 and 100 pg terbufos 1-' with an acetone and seawater control for each temperature/salinity combination. Test durations were temperature dependent and ranged from 5 to 14 d. Endpoints were embryo survival, hatching and percentage of larvae with normal vertebrae. Embryo survival was significantly ( a = 0.05) lower in tests conducted at 20°C for all salinities. Salinity affected survival only at combinations of 20%0 and 100 ~g terbufos I-' Both temperature and salinity affected the percentage hatch, wlth the lowest hatching occurring in tests at 20 "C and in tests conducted at 20 L. The percentage of larvae with normal vertebrae was significantly (a = 0.05) reduced from controls at terbufos concentrations of 25 (7 to 32 %), 50 (44 to 62 %) and 100 pg 1-' (58 to 73 %) for the 3 temperatures tested, whereas salinity showed no significant effect. Anomalies in the development of vertebrae occurred across all temperature and salinity combinations, and were observed at concentrations as low as 12.5 pg terbufos 1-'

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Section: Methodsmentioning

confidence: 99%

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Hemmer¹,

Middaugh²,

Moore³

1990

Dis. Aquat. Org.

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“…2), and the chance that larvae were exposed to salinities <10‰ was minimal. Pericardial edema has been described in many developmental studies with several fish species and different toxicants (Waterman 1940;Weis and Weis 1974;Dial 1978;Gillespie and Baumann 1986;Middaugh et al 1988;Marty et al 1990), but ascites is less often described. Ascites was the main lesion associated with blue-sac disease in wild lake trout (Salvelinus namaycush) larvae, and ascites also occurred in lake trout larvae exposed to 2,3,7,8-tetrachlorodibenzo-pdioxin as fertilized eggs (Symula et al 1990;Spitsbergen et al 1991).…”

Section: Level Of Significancementioning

confidence: 97%

Histopathology and cytogenetic evaluation of Pacific herring larvae exposed to petroleum hydrocarbons in the laboratory or in Prince William Sound, Alaska, after the Exxon Valdez oil spill

Marty¹,

Hose²,

McGurk³

et al. 1997

Can. J. Fish. Aquat. Sci.

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Following the 1989 Exxon Valdez oil spill in Prince William Sound, Alaska, USA, Pacific herring (Clupea pallasi) larvae sampled from oiled sites had ascites, pericardial edema, and genotoxic damage. Laboratory study confirmed that these lesions were consistent with oil exposure. Pacific herring larvae were trawled from two oiled and two unoiled sites in Prince William Sound in May 1989. Larvae from oiled sites were shorter, had ingested less food, had slower growth (oiled, 0.07-0.10 mm/day; unoiled, 0.15-0.18 mm/day), and had higher prevalence of cytogenetic damage (oiled, 56-84%; unoiled, 32-40%) and ascites (oiled, 16%; unoiled, 1%) than from unoiled sites. In the laboratory experiment, Pacific herring eggs were exposed to an oil-water dispersion of Prudhoe Bay crude oil (initial concentrations of 0.0, 0.10, 0.24, 0.48, and 2.41 mg/L) and sampled for histopathology <24 h after hatching. Effects were significant at the 0.48 mg/L dose (Dunnett's procedure, P < 0.05). Lesions included ascites; hepatocellular vacuolar change; and degeneration or necrosis of skeletal myocytes, retinal cells, and developing brain cells. Lesions in field-sampled larvae were consistent with higher mortality rates documented in larvae from oiled sites.Résumé : Après le déversement pétrolier de l'Exxon Valdez qui a eu lieu en 1989 dans le golfe du Prince-William, Alaska, É.-U., des larves de hareng du Pacifique (Clupea pallasi), prélevées dans des sites exposés au pétrole présentaient des ascites, de l'oedème péricardique et des lésions génotoxiques. Une étude en laboratoire a confirmé qu'il y avait compatibilité entre ces lésions et l'exposition au pétrole. Des larves de hareng du Pacifique ont été récoltées par chalutage dans deux sites exposés au pétrole et dans deux sites non exposés dans le golf du Prince-William en mai 1989. Les larves provenant des sites exposés étaient plus courtes, avaient ingéré moins d'aliments, avaient une croissance plus lente (site exposé, 0,07-0,10 mm/jour; site non exposé, 0,15-0,18 mm/jour) et présentaient une fréquence plus élevée de lésions cytogénétiques (site exposé, 56-84 %; site non exposé, 32-40 %) et d'ascites (site exposé, 16 %; site non exposé, 1 %) que les larves provenant des sites non exposés au pétrole. Au cours d'une expérience de laboratoire, des oeufs de hareng du Pacifique ont été exposés à une dispersion pétrole-eau de pétrole brut de Prudhoe Bay (concentrations initiales de 0,0, 0,10, 0,24, 0,48 et 2,41 mg/L) et ont été examinés pour déceler des manifestations histopathologiques moins de 24 h après leur éclosion. Les effets étaient statistiquement significatifs à la dose d'exposition de 0,48 mg/L (méthode de Dunnett, P < 0,05). Parmi les lésions figuraient des ascites, des modifications vacuolaires hépatocellulaires et une dégénérescence ou une nécrose des myocytes squelettiques, des cellules rétiniennes et des cellules cérébrales en développement. Les lésions chez les larves échantillonnées sur le terrain correspondaient avec les taux de mortalité élevés documentés chez les larves pr...

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“…beryllina embryo tests were only used to evaluate virulence of M. anisopliae 1080 conidiospores. Embryonic M. beryllina were obtained from adults that spawned naturally in the laboratory at 5% salinity and 25°C as described by Middaugh et al (1987Middaugh et al ( , 1988. The photoperiod was 16 h light and 8 h dark.…”

Section: Inland Silversides (Menidia Beryllina) Embryo Testsmentioning

confidence: 99%

Toxicity and Pathogenicity Testing of the Insect Pest Control Fungus Metarhizium anisopliae

Genthner

Chancy

Couch

et al. 1998

Archives of Environmental Contamination and Toxicology

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Renewed interest in the use of Metarhizium anisopliae and its toxins for insect control prompted the following safety assessment. A neutral extract (methylene chloride, pH 7.2), derived from M. anisopliae cultures, was evaluated for toxicity and mutagenicity using aquatic animal bioassays and the Ames test. The average LC50 of the neutral extract obtained in static, acute 96-h tests conducted with 0.05) mortalities or malformations.

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Teratological effects of 2,4-dinitrophenol, produced water' and naphthalene on embryos of the inland silverside Menidia beryllina

Cited by 30 publications

References 15 publications

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Histopathology and cytogenetic evaluation of Pacific herring larvae exposed to petroleum hydrocarbons in the laboratory or in Prince William Sound, Alaska, after the Exxon Valdez oil spill

Toxicity and Pathogenicity Testing of the Insect Pest Control Fungus Metarhizium anisopliae

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