“…Furthermore, the limited number of samples does not allow us to evaluate our results as a function of age, sex, frequency of attacks, and duration, which, in light of the above-mentioned considerations on the maturation process in children and variations in phenotype during developmental ages [2,3], are aspects that should not be overlooked. The absence in the control population of subjects suffering from tension-type headaches is an aspect that will need to be examined because at a developmental age, the boundaries between the two disorders are less clear than in adulthood, and there is frequently a transition from one form of headache to the other (more frequently from a tension-type headache to migraine) [46,47]. Finally, it would also be appropriate to compare our results with other non-invasive methods such as evoked potentials, quantitative EEG, etc., in the same subjects [48].…”