Tendência dos casos de sífilis gestacional e congênita em Minas Gerais, 2009-2019: um estudo ecológico

Amorim, Evlhin Karolline Ramos; Matozinhos, Fernanda Penido; Araújo, Laydson Adrian de; Silva, Thales Philipe Rodrigues da

doi:10.1590/s1679-49742021000400006

Cited by 11 publications

(10 citation statements)

References 14 publications

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“…Esta realidade corrobora com a que foi identificada em outros estudos realizados em São Paulo, Minas Gerais, Mato Grosso do Sul e Tocantins 24,[28][29][30] . A respeito da variável raça/cor, este estudo aquiesceu o resultado em estudo realizado em 2019, pois o trabalho concluiu frequência mulheres brancas em 66% dos casos 24 .…”

Section: Resultsunclassified

Análise do perfil epidemiológico de gestantes com sífilis no Paraná, 2010-2020

Silva

Forlin

Charlo

et al. 2022

GANJ

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ResumoO presente estudo objetivou analisar o perfil epidemiológico das gestantes com sífilis no Paraná, entre 2010 e 2020 através de um estudo quantitativo, descritivo, baseado em dados secundários originários do Departamento de Informática do Sistema Único de Saúde. Notificou-se 18.681 casos de sífilis em gestantes, dentro do universo estudado, avaliou-se as seguintes variáveis, idade, cor e raça, escolaridade, classificação clínica e o tipo de diagnóstico. Mulheres de 20 a 39 anos, brancas, com ensino fundamental de 5ª a 8ª série incompleto foram as mais acometidas nesta amostra. Quanto ao diagnóstico, 80,5% e 86,1% das gestantes tiveram o teste treponêmico e não treponêmico reativos, respectivamente. Já em relação à sífilis congênita, foram registrados 6.212 casos, tendo como variáveis, a realização do pré-natal, momento do diagnóstico, classificação final, evolução dos nascidos vivos e realização do tratamento pelo parceiro. Constatou-se que, predominantemente, as mães realizaram o pré-natal, tiveram seu diagnóstico durante o mesmo, evidenciando a importância da assistência à saúde materna, também foi identificada baixa adesão dos parceiros ao tratamento da infecção, sendo necessário intensificar a atenção à saúde gravídico-puerperal para atingir o objetivo final de reduzir a sífilis congênita.

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Section: Resultsunclassified

Análise do perfil epidemiológico de gestantes com sífilis no Paraná, 2010-2020

Silva

Forlin

Charlo

et al. 2022

GANJ

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“…In Minas Gerais, from 2009 to 2019, the incidence rates of gestational and CS had an average percentual annual increase of 36.7% and 32.8%, respectively, suggesting failure on the syphilis treatment during the prenatal 21. In Amazonas, Ceará, Federal District, Espírito Santo, Rio de Janeiro and Rio Grande do Sul, 43% of women who received a diagnosis of gestational syphilis progressed to CS, 59% of them received inadequate treatment, 25% were untreated and only 7.9% of partners were treated 22.…”

Section: Discussionmentioning

confidence: 99%

Spatial scenery of congenital syphilis in Brazil between 2007 and 2018: an ecological study

Seabra

Ferreira

Sörensen³

et al. 2022

BMJ Open

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ObjectiveTo analysis the epidemiological scenery of the congenital syphilis (CS) in Brazil employing spatial analysis techniques.DesignEcological study.SettingsThis study was conducted in BrazilSampleA total of 151 601 CS cases notified to the Diseases and Notification Information System from 2007 to 2018 from children aged 0–23 months and born from mothers living in Brazil were included in this study.Primary outcome measuresThe CS incidence rates were calculated by triad (2007–2010, 2011–2014 and 2015–2018) for all Brazilian municipalities following the Boxcox transformation to remove the discrepant values. The transformed rates were analysed through the spatial autocorrelation of Moran, Kernel density estimative and spatial scan.ResultsFrom 2007 to 2018, the CS incidence rates increased in all Brazilian regions. The CS spread towards the interior of Brazil, and a higher expansion was noticed between 2015 and 2018. The municipalities that were greatly affected by the CS were those having a high migration of people, such as the ones bordering other countries and the touristic cities. Recife, Campo Grande, Rio de Janeiro, Porto Alegre and Manaus were the capitals with the greatest spatial and spatiotemporal risk.ConclusionThis study provides assistance to health authorities to fight CS in Brazil. More investment is necessary in prenatal care quality focusing on pregnant women and their partners to guarantee their full access to preventive resources against sexually transmitted infections.

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“…Information regarding CS vertical transmission should be provided to pregnant women at the onset of prenatal care, and physicians must inform patients regarding the risks and consequences of the disease to the mother and her fetus [ 32 , 42 ]. Nonetheless, difficulties in diagnosis, interruption of and/or low attendance in prenatal examinations, non-adherence or inadequate treatment regarding antibiotic dosage, and absence of partners at prenatal appointments have been reported as risk factors for the development and non-interruption of syphilis [ 42 – 47 ].…”

Section: Discussionmentioning

confidence: 99%

“…The present study identified spatial clusters of municipalities with high rates of CS and SiP in Brazil. Between 2001 and 2017, almost all regions and microregions of the country reported a higher intensity of CS and SiP infections [ 47 , 54 , 57 – 62 ]. However, in most of Brazil’s microregions, there are few studies of these regions that do not highlight these areas as priority for a syphilis surveillance study.…”

Section: Discussionmentioning

confidence: 99%

Spatiotemporal distribution analysis of syphilis in Brazil: Cases of congenital and syphilis in pregnant women from 2001–2017

Silva

Leony²,

Souza³

et al. 2022

PLoS ONE

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In Brazil, the notification of congenital (CS) and syphilis in pregnant women (SiP) is compulsory. Notification data provided by the Ministry of Health in combination with the mapping of vulnerable geographic areas is essential to forecasting possible outbreaks and more effectively combating infection through monitoring. We aim to evaluate the spatiotemporal distribution and epidemiological aspects of reported cases of CS and SiP in Brazil. A retrospective ecological study was carried out using secondary surveillance data obtained from the Brazilian National Notifiable Diseases Information System (SINAN) database, considering all reported cases of CS and SiP between 2001 to 2017. Epidemiological characteristics and time trends were analyzed using joinpoint regression models and spatial distribution, considering microregions or states/macroregions as units of analysis. A total of 188,630 (359/100,000 birth lives) CS and 235,895 of SiP (6.3/100,000 inhabitants) were reported during the period studied. In general, the epidemiologic profile of Brazil indicates most reported CS cases occurred in "mixed-race" newborns who were diagnosed within seven days of birth and whose mothers had received prenatal care, but the epidemiologic profile varies by Brazilian macroregion. Regarding SiP, most cases were among women who self-reported ‘mixed-race’, were aged 20–39 years, had up to eight years of formal education and were diagnosed with primary or latent syphilis. Approximately 549 (98.4%) and 558 (100%) microregions reported at least one case of CS and SiP, respectively. From 2012 to 2016, CS cases increased significantly in almost all Brazilian states, most notably in the South, Southeast, and Central-West macroregions, from 2001–2017 and the relative risk (RR) of SiP increased around 400% (RR: 1,00 to 445,50). Considering the epidemiological scenario of the infection in Brazil, it is necessary to enhance preventive, control and eradication measures.

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Tendência dos casos de sífilis gestacional e congênita em Minas Gerais, 2009-2019: um estudo ecológico

Cited by 11 publications

References 14 publications

Análise do perfil epidemiológico de gestantes com sífilis no Paraná, 2010-2020

Análise do perfil epidemiológico de gestantes com sífilis no Paraná, 2010-2020

Spatial scenery of congenital syphilis in Brazil between 2007 and 2018: an ecological study

Spatiotemporal distribution analysis of syphilis in Brazil: Cases of congenital and syphilis in pregnant women from 2001–2017

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