Ten-year treatment outcomes including blood cell count disturbances in patients with simple renal cysts

Abstract

BackgroundThe simple renal cyst is the most common benign kidney disease. It may cause pain and hypertension, especially if significantly enlarged. As in polycystic kidney disease, blood cell count disturbances are frequently observed in simple renal cysts. The aim of our study was to assess such disturbances, changes in blood pressure, and complication rate in our patients undergoing surgery due to simple renal cyst in the last 10 years.Material/Methods210 patients with simple renal cysts were underwent surgery between 2002 and 2012. Two different kinds of operation were conducted: aspiration of cyst fluid with injection of sclerosing agent, and laparoscopic/retroperitoneoscopic decortications of the cyst wall. A control group comprised 134 patients with benign prostate hyperplasia. The following data were obtained: cyst burden, hematocrit, hemoglobin, red blood cells, thrombocytes, occurrence of pain, and blood pressure before and after the operation. Complications were collected and presented in Clavien score.ResultsHematocrit, hemoglobin, and red blood cells were significantly increased in the experimental group. A positive correlation was observed between cyst burden and the parameters mentioned above. Of 91 patients with hypertension, 56 (61.7%) had blood pressure reduction after the operation. Treatment relieved the loin pain in 132 (88%) patients. Complications occurred in 15 (7.4%) patients.ConclusionsPatients with simple renal cysts have high values of red blood cells, hematocrit, and hemoglobin. Treatment decreases blood pressure in patients with hypertension. Complications after treatment are rare and mild.

Natural 10-year history of simple renal cysts

“…Approximately 2% to 4% of SRCs may become symptomatic (abdominal pain or hematuria) owing to increasing size (6-8 cm) or a complication like infection, hemorrhage, or rupture [ 6 ]. Numerous studies have reported that renal cysts can cause hypertension, which frequently resolves after cyst removal [ 9 ] or aspiration [ 10 ]. One surgical study involving treatment of patients with large renal cysts (mean cyst size, 7.45 cm) suggested a beneficial effect on blood pressure (overall decrease or antihypertensive therapy reduction) in 62% of patients [ 9 ].…”