Natural 10-year history of simple renal cysts

Abstract

PurposeTo carry out long-term follow-up of patients diagnosed with asymptomatic simple renal cysts (SRCs).Materials and MethodsOne hundred fifty-eight adult patients in whom SRCs were incidentally diagnosed by abdominal ultrasonography or abdominopelvic computed tomography between August 1994 and June 2004 were followed up for over 10 years. The retrospective analysis investigated sequential changes in the size, shape, and Bosniak classification of the renal cyst and analyzed risk factors for increased size and growth rate of the cysts.ResultsThe median follow-up period was 13.9 years (range, 10.0-19.8 years). Median patient age was 54.1 years (range, 22-86 years). Mean maximal cyst size was 33 mm (range, 2-90 mm). Among all patients, 120 (76%) showed a mean increase in maximum renal cyst diameter of 1.4 mm (6.4%) per year. Age at initial diagnosis was a risk factor for increased renal cyst maximum diameter. The probability of an increase in maximum diameter of an SRC was 7.1 times greater in patients aged 50 years or older at diagnosis than in those aged less than 50 years. However, among patients with an increased maximum diameter, the mean growth rate was lower in patients aged ≥50 years than in those aged <50 years.ConclusionsAbout three-quarters of adult patients with accidentally diagnosed SRCs presented with an increased maximum diameter. The only risk factor for an increase in maximum diameter was age. In patients with an increase in the maximum diameter, the growth rate of the maximum diameter was 6.4% per year during 10 years and decreased with age.

CUA guideline on the management of cystic renal lesions

“…One should remember that the natural history of these cysts is that the majority will grow over time and thus, growth should not necessarily be considered a sign a malignancy. 52,53 Transformation into a more complex cyst is rare and has been reported in only a handful of cases. [52][53][54][55][56][57] As this is rare in occurrence, these cysts do not require followup.…”

Percutaneous ureteroscopy laser unroofing-a minimally invasive approach for renal cyst treatment

“…Renal cysts remain the most common types of benign renal lesions, and represent more than 70% of asymptomatic renal masses 2 , 13 . Regarding the risk factors for the development of cysts, increasing age, male gender, the presence of hypertension, and the presence of renal insufficiency were all associated with the development of sporadic renal cysts 14 .…”

“…Renal cysts are simple benign lesions with an unknown etiology that are either inherited or acquired. The kidney is one of the most common sites of cyst formation in the human body; the estimated prevalence of renal cysts is approximately 10% of the general population, and the incidence increases with age 1 , 2 . Most renal cysts are simple cysts and are asymptomatic, and many of them are found incidentally through routine physical examinations and rarely require therapy 3 .…”

Comparative analysis of surgical treatment outcomes in children with solitary renal cysts

“…Увеличение числа кистозных заболеваний почек, прежде всего, связано с ростом выявляемости данной патологии в результате повсеместного внедрения ультразвуковых и компьютерно-томографических методов диагностики [6,7,8,9].…”