Ten-Year Incidence of Retinal Emboli in an Older Population

Cugati, Sudha; Wang, Jie Jin; Rochtchina, Elena; Mitchell, Paul

doi:10.1161/01.str.0000204118.87477.46

Cited by 36 publications

(17 citation statements)

References 17 publications

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“…Other studies have reported a cumulative incidence of 1.5–2.9% over 10 years [8, 9], which is similar to our finding. In the first year of the screening program, the prevalence of retinal emboli in the local area was 1.5% (personal communication with DHW Steel).…”

Section: Discussionsupporting

confidence: 93%

Assessing Patients with Asymptomatic Retinal Emboli Detected at Retinal Screening

et al. 2016

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IntroductionAsymptomatic retinal emboli have been associated with diabetes, the presence of significant carotid artery stenosis (≥70%) and an increased risk of stroke. However, there is no clear guidance on how best to investigate and manage patients found to have asymptomatic retinal emboli. Therefore, this study aimed to assess the incidence of significant carotid artery stenosis in patients found to have asymptomatic retinal emboli at diabetic retinopathy screening, and to examine disease management approaches among these patients.MethodsPatients with new retinal emboli visible at diabetic retinopathy screening were referred to a medical retinopathy clinic and underwent examinations according to a standardized protocol, including carotid Doppler ultrasound and echocardiography. Case notes of patients referred between January 2013 and April 2014 were reviewed. Results of investigations, medication changes and the number of patients who underwent relevant surgical interventions were noted.ResultsRetinal emboli were present in 44 of 13,643 people screened (0.32%). Full data were available for 39 patients. Twenty-two patients (56%) had relevant medication changes. Nine (23%) patients had significant carotid artery stenosis. One underwent carotid endarterectomy, and eight received maximal medical therapy.ConclusionSignificant carotid artery stenosis was not uncommon in patients with incident retinal emboli at retinal screening. The referral and investigation protocols identified individuals at risk of cerebrovascular events and led to optimized management. Pathways utilizing Doppler ultrasound and physician referral should be more widely implemented.

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Section: Discussionsupporting

confidence: 93%

Assessing Patients with Asymptomatic Retinal Emboli Detected at Retinal Screening

et al. 2016

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“…The BMES showed that 18% of people with retinal emboli compared to 12% without had non‐diabetic retinopathy lesions but the statistical significance was unreported . The 10 year follow‐up of the BMES cohort showed that AV nicking, arteriolar wall opacification and retinal vein occlusion predict incident retinal embolism . Other microvascular parameters such as focal or general arteriolar narrowing have not shown association with the presence of retinal emboli so far in cross‐sectional or prospective population‐based studies.…”

Section: Retinal Arteriolar Emboli and Occlusionmentioning

confidence: 97%

“…Although less frequently reported than the other retinal vascular disease states, there is no evidence of associations between retinal microvascular changes and prevalent or incident retinal embolism (Table ). This is with the exception of the BDES where at the 5 year analysis, the presence of retinopathy in non‐diabetic subjects had a fourfold higher risk of prevalent embolism; however, no measures were associated with incident emboli at either the 5 or 10 year analysis .…”

Section: Retinal Arteriolar Emboli and Occlusionmentioning

confidence: 99%

Review of the association between retinal microvascular characteristics and eye disease

Newman

Andrew

Casson

2017

Clinical Exper Ophthalmology

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Computerized retinal imaging technologies enable the static and dynamic measurement of a range of retinal microvascular parameters. Large population-based studies have reported associations between these microvascular indices and various ophthalmic diseases including diabetes, age-related macular degeneration, retinal artery embolism, retinal vein occlusion, glaucoma and non-glaucomatous optic neuropathies. Increasingly, sophisticated imaging and analysis techniques have the potential to provide relevant clinical information regarding disease risk and progression; however, further studies are required to verify associations and strengthen the predictive power of these techniques. We summarize the current state of knowledge regarding retinal microvascular characteristics and eye disease.

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“…Risk factors for the development of CRAO are similar to those of other cardiovascular diseases, namely increasing age, hypertension, hypercholesterolemia, diabetes, elevated homocysteine levels, and tobacco use. Some studies have described an increased incidence in males, whereas others have failed to demonstrate a difference in disease prevalence in one sex over the other [46][47][48].…”

Section: Epidemiologymentioning

confidence: 99%

Acute Monocular Visual Loss

Vortmann¹,

Schneider²

2008

Emergency Medicine Clinics of North America

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Ten-Year Incidence of Retinal Emboli in an Older Population

Abstract: Background and Purpose-To assess 10-year incidence of retinal emboli and its predictors in an older population. Methods-Survivors of 3654 Blue Mountains Eye Study participants Ն49 years of age were re-examined 5 and 10 years later. Incident emboli were assessed from retinal photographs.

Cited by 36 publications

References 17 publications

Assessing Patients with Asymptomatic Retinal Emboli Detected at Retinal Screening

Assessing Patients with Asymptomatic Retinal Emboli Detected at Retinal Screening

Review of the association between retinal microvascular characteristics and eye disease

Acute Monocular Visual Loss

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