Ten-year Follow-up of Photorefractive Keratectomy for Myopia of Less Than −6 Diopters

Alió, Jorge L.; Müftüoğlu, Orkun; Ortiz, Dolores; Artola, Alberto; Pérez-Santonja, Juan J; Luna, Gracia Castro de; Abu-Mustafa, Sabat K.; García, Maria José

doi:10.1016/j.ajo.2007.09.007

Cited by 63 publications

(52 citation statements)

References 27 publications

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“…Despite the fact that many papers have been published, few studies have reported the long-term outcome of PRK over more than 10 years [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 96%

Ten-year follow-up of photorefractive keratectomy for myopia

Koshimizu

Dhanuka

Yamaguchi

2010

Graefes Arch Clin Exp Ophthalmol

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“…Despite the fact that many papers have been published, few studies have reported the long-term outcome of PRK over more than 10 years [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 96%

Ten-year follow-up of photorefractive keratectomy for myopia

Koshimizu

Dhanuka

Yamaguchi

2010

Graefes Arch Clin Exp Ophthalmol

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“…Cornea laser refractive surgery has become generally accepted as a safe approach for correcting low-to-moderate refractive errors, and satisfactory visual acuity outcomes have been widely reported (1) . Nevertheless, the quality of vision may be altered due to changes in contrast sensitivity, glare, and/or higher-order aberrations (2) .…”

Section: Introductionmentioning

confidence: 99%

Intraocular straylight before and after low myopic photorefractive keratectomy with and without mitomycin C

Torricelli¹,

Parede²,

Netto³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Purpose: To evaluate ocular straylight before and after photorefractive keratectomy (PRK) for low myopia with and without topical mitomycin (MMC) treatment. Methods: Patients who underwent PRK for low myopia were enrolled into the study. PRK without MMC was performed in 21 eyes (12 patients), whereas PRK with topical 0.02% MMC was performed in 25 eyes (14 patients). Both groups were treated using the NIDEK EC5000 excimer laser. Measurements were performed using the C-Quant straylight meter preoperatively and at two and four months postoperatively. Results: The mean patient age was 30 ± 4 years, and the mean spherical equivalent refractive error was -2.2 ± 0.75 D. The mean preoperative intraocular straylight values were 1.07 ± 0.10 in the PRK without MMC group and 1.07 ± 0.11 log(s) in the PRK with topical MMC group. At two months after surgery, there was a decrease in mean intraocular straylight values in both groups. However, a significant difference was only reached in the PRK with MMC group [0.98 ± 0.09 log(s), p=0.002] compared with preoperative values, which was likely due to a greater scatter of measurements in the PRK without MMC group [1.03 ± 0.13 log(s), p=0.082]. At four months postoperatively, ocular straylight values were not significantly different compared with those at baseline in either the PRK without MMC group [1.02 ± 0.14 log(s), p=0.26] or in the PRK with topical MMC group [1.02 ± 0.11 log(s), p=0.13]. Conclusion: PRK for low myopia decreases ocular straylight, and MMC application further reduces straylight in the early postoperative period. However, ocular straylight values do not significantly differ at four months after surgery compared with those at baseline. (1,02 ± 0,14 log(s), p=0,26) quanto no grupo com MMC tópica (1,02 ± 0,11 log(s), p=0,13). Keywords meses da cirurgia houve uma diminuição na média da dispersão de luz intraocular em ambos os grupos. Entretanto uma diferença estatisticamente significante, comparado com os valores préoperatórios, foi observada apenas no grupo PRK com MMC (0,98 ± 0,09 log(s), p=0,002), provavelmente devido as medidas com maior espalhamento de luz no grupo sem MMC (1,03 ± 0,13 log(s), p=0,082). Após 4 meses de pósoperatório, os valores de dispersão de luz não apresentavam diferença estatisticamente significantes quando comparados com os valores iniciais, tanto no grupo sem MMC Conclusão: PRK para baixa miopia diminui a dispersão de luz ocular e a aplicação de MMC contribui para uma ainda menor dispersão de luz no período pósoperatório inicial. Entretanto, quatro meses após a cirurgia a dispersão de luz intraocular não é significantemente diferente das medidas préoperatórias.Descritores: Ceratectomia fotorrefrativa; Miopia/cirurgia; Mitomicina; Cicatrização this as a troubling symptom, at least in the early postoperative period, following procedures such as photorefractive keratectomy (PRK).Disability glare is the veiling of vision due to the forward scattering of light in the eye (5,6) . Straylight is a known source of disability glare (7) . Th...

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“…Some authors have performed retouches to the surface ablation without MMC, and found no significant incidence of postoperative haze in the treatment of residual myopia. (31,32) However, the tendency to develop haze is directly proportional to the number of retreatments. Several studies have reported post-operative opacity in eyes that had PRK and subsequent LASIK without the use of MMC.…”

Section: As Adjuvant Therapy After Prkmentioning

confidence: 99%

Mitomycin C application in refractive surgery

Piva¹,

Santhiago²

2015

Revista Brasileira De Oftalmologia

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Over the years, mitomycin C has been used by refractive surgeons to prophylactically decrease haze after surface ablation procedures and therapeutically in the treatment of preexisting haze. Development of mitomycin C treatments has had a significant role in the revival RESUMOA mitomicina C teve seu uso profilático e terapêutico estabelecido, ao longo dos anos, para diminuir o haze depois da ablação superficial. A mitomicina C é segura e eficaz como uma terapia adjuvante aplicada após um procedimento primário de ceratectomia fotorrefrativa ou após um retratamento com ceratectomia fotorrefrativa após o laser in situ keratomileusis LASIK. A mitomicina age modulando a cicatrização após a cirurgia. Constitui-se num potente inibidor de mitose, bloqueia a ativação e a profliferação dos fibroblastos e a diferenciação dos miofibroblastos. Embora existam muitos estudos apontando a segurança da mitomicina nas doses ultilizadas, ainda persistem dúvidas quanto à segurança, a longo prazo, do uso da mitomicina. Quando as córneas são examinadas com microscópios confocal, após depleção inicial dos ceratócitos, a densidade celular parece retornar ao normal seis a 12 meses após o uso de mitomicina C . A maioria dos estudos clínicos não encontrou diferença significativa entre a densidade endotelial celular pré-operatória e pós-operatória quando a mitomicina C 0.02% foi aplicada durante a cirurgia com um tempo de exposição de 2 minutos ou menos. Em aproximadamente 14 anos, a mitomicina C mostrou-se eficaz na prevenção e tratamento do haze corneano.

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Ten-year Follow-up of Photorefractive Keratectomy for Myopia of Less Than −6 Diopters

Abstract: Photorefractive keratectomy for myopia of less than -6 D is a safe and effective procedure in the long-term.

Cited by 63 publications

References 27 publications

Ten-year follow-up of photorefractive keratectomy for myopia

Ten-year follow-up of photorefractive keratectomy for myopia

Intraocular straylight before and after low myopic photorefractive keratectomy with and without mitomycin C

Mitomycin C application in refractive surgery

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