Temporal trends and long term follow-up of implantable cardioverter defibrillator therapy for secondary prevention: A 15-year single-centre experience

Caputo, Maria Luce; Regoli, François; Conte, Giulio; Adjibodou, Boris; Svab, Stefano; Bufalo, Alessandro Del; Moccetti, Tiziano; Curti, Moreno; Klersy, Catherine; Auricchio, Angelo

doi:10.1016/j.ijcard.2016.11.071

Cited by 5 publications

(5 citation statements)

References 24 publications

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“…Among them, 42% (305/730) were patients with ischemic heart disease (IHD). This result was similar to our previous report that in the Asia–Pacific region, the proportion of SCD due to IHD was lower compared to that in the Caucasian populations in which nearly 80% of the SCD patients were due to IHD 11 , 18 , 19 .…”

Section: Resultssupporting

confidence: 91%

“…We found patients with history of MI, older age and LQTS were probably more susceptible to arrhythmic death. Therefore, the follow-up and treatment should be more scrutinized in these patients, such as more frequent ICD interrogation to detect non-sustained ventricular arrhythmia, more aggressive medical treatment or higher dose of beta blocker, and avoid drugs that predispose to ventricular arrhythmia (class I anti-arrhythmic drugs) 1 , 13 , 18 . For those with prior MI and history of SCD or ventricular arrhythmia, early and more frequent stress test to detect subtle myocardial ischemia, institution of early coronary intervention, and more intensive statin treatment may be warranted 43 – 45 .…”

Section: Discussionmentioning

confidence: 99%

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Unique clinical features and long term follow up of survivors of sudden cardiac death in an Asian multicenter study

Huang

Cheng

et al. 2021

Sci Rep

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There has been no long-term clinical follow-up data of survivors or victims of sudden cardiac death (SCD). The Taiwan multi-center sudden arrhythmia death syndrome follow-up and clinical study (TFS-SADS) is a collaborative multi-center study with median follow-up time 43 months. In this cohort, the clinical characteristics of these SADS patients were compared with those with ischemic heart disease (IHD). In this SCD cohort, around half (42%) were patients with IHD, which was different from Caucasian SCD cohorts. Among those with normal heart, most had Brugada syndrome (BrS). Compared to those with SADS, patients with IHD were older, more males and more comorbidities, more arrhythmic death, and lower left ventricular ejection fraction. In the long-term follow-up, patients with SADS had a better survival than those with IHD (p < 0.001). In the Cox regression analysis to identify the independent predictors of mortality, older age, lower LVEF, prior myocardial infarction and history of out-of-hospital cardiac arrest were associated with higher mortality and beta blocker use and idiopathic ventricular fibrillation or tachycardia (IVF/IVT) with a better survival during follow-up. History of prior MI was associated with more arrhythmic death. Several distinct features of SCD were found in the Asia–Pacific region, such as higher proportion of SADS, poorer prognosis of LQTS and better prognosis of IVF/IVT. Patients with SADS had a better survival than those with IHD. For those with SADS, patients with channelopathy had a better survival than those with cardiomyopathy.

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Section: Resultssupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Unique clinical features and long term follow up of survivors of sudden cardiac death in an Asian multicenter study

Huang

Cheng

et al. 2021

Sci Rep

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“…Nine studies 4,[9][10][11]14,15,18,27,28 with 3680 patients assessed the association of AF and appropriate shock therapy among patients with ICD. Studies used an inconsistent protocol for ICD programming, which have been summarized in Table 3.…”

Section: Appropriate Shock Therapymentioning

confidence: 99%

Atrial Fibrillation Is Associated With Higher Overall Mortality in Patients With Implantable Cardioverter‐Defibrillator: A Systematic Review and Meta‐Analysis

Mustafa

Dherange

Reddy

et al. 2018

JAHA

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Background Implantable cardioverter‐defibrillator ( ICD ) improves survival when used for primary or secondary prevention of sudden cardiac death. Whether the benefits of ICD in patients with atrial fibrillation ( AF) are similar to those with normal sinus rhythm ( NSR ) is not well established. The aim of this study is to investigate whether ICD patients with AF are at higher risk of mortality and appropriate shock therapy compared with patients with NSR . Methods and Results Literature was searched and 25 observational studies with 63 283 patients were included in this meta‐analysis. We compared the outcomes of (1) all‐cause mortality and appropriate shock therapy among AF and NSR patients who received ICD for either primary or secondary prevention and (2) all‐cause mortality among AF patients with ICD versus guideline directed medical therapy. All‐cause mortality (odds ratio, 2.11; 95% confidence interval, 1.73–2.56; P <0.001) and incidence of appropriate shock therapy (odds ratio, 1.77; 95% confidence interval, 1.47–2.13; P <0.001) were significantly higher in ICD patients with AF as compared to NSR . There was no statistically significant mortality benefit from ICD compared with medical therapy in AF patients (odds ratio, 0.69; 95% confidence interval, 0.42–1.11; P =0.12) based on a separate meta‐analysis of 3 studies with 387 patients. Conclusions Overall mortality and appropriate shock therapy are higher in ICD patients with AF as compared with NSR . The impact of ICD on all‐cause mortality in AF patients when compared to goal‐directed medical therapy is unclear, and randomized controlled trials are needed comparing AF patients with ICD and those who have indications for ICD, but are only on medical therapy.

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“…Although it was anticipated that the appropriate shock rate would be higher in the Japanese population since there were more patients receiving the device for secondary prevention, results from this report showed that the incidence of appropriate shock was similar between JPN and OJPN (Figure ). This may be related to the fact that the Japanese population in this study comprises patients with relatively good cardiac function, lower incidence of myocardial infarction, and fewer patients with ischemic cardiomyopathy, all of which have been reported to predict incidence of appropriate therapy (Online Appendix Figure ) . Further research is warranted.…”

Section: Discussionmentioning

confidence: 99%

“…This may be related to the fact that the Japanese population in this study comprises patients with relatively good cardiac function, lower incidence of myocardial infarction, and fewer patients with ischemic cardiomyopathy, all of which have been reported to predict incidence of appropriate therapy (Online Appendix Figure S2). 16 Further research is warranted.…”

Section: Appropriate Shock Ratementioning

confidence: 99%

Comparison of ICD shock rates in Japanese and non‐Japanese patients in the PainFree SST study

Kurita

Ando

Ueda

et al. 2018

Pacing Clinical Electrophis

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Temporal trends and long term follow-up of implantable cardioverter defibrillator therapy for secondary prevention: A 15-year single-centre experience

Cited by 5 publications

References 24 publications

Unique clinical features and long term follow up of survivors of sudden cardiac death in an Asian multicenter study

Unique clinical features and long term follow up of survivors of sudden cardiac death in an Asian multicenter study

Atrial Fibrillation Is Associated With Higher Overall Mortality in Patients With Implantable Cardioverter‐Defibrillator: A Systematic Review and Meta‐Analysis

Comparison of ICD shock rates in Japanese and non‐Japanese patients in the PainFree SST study

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