Temporal investigation of percutaneous coronary intervention for non-ST segment elevation acute coronary syndrome

Abstract

Background: Percutaneous coronary intervention is the most recommended method of myocardial revascularization in acute coronary syndrome patients. The objective of this study was to analyze the clinical profiles and outcomes of patients with non-ST segment elevation acute coronary syndrome undergoing percutaneous coronary intervention. Methods: We retrospectively analyzed 53,889 patients with non-ST segment elevation acute coronary syndrome, who underwent percutaneous coronary intervention between June 2006 and March 2016. A database was used to define the patients' clinical and angiographic characteristics, procedures and clinical outcomes. The patients were grouped into different chronological periods, and variables were analyzed to determine their influence over death outcomes. Results: Factors such as advanced age, female sex, history of infarction or coronary artery bypass surgery, diabetes, multivessel disease, left ventricular dysfunction, and collateral circulation were associated to a higher risk of in-hospital death for these patients. The success rate of the procedures increased along time and the risk of death decreased. Conclusion: Advances in the available medical technology have changed the profile of percutaneous coronary intervention, which has led to a higher rate of procedure success and a lower risk of death and complications.