Temporal Detection and Phylogenetic Assessment of SARS-CoV-2 in Municipal Wastewater

Nemudryi, Artem; Nemudraia, Anna; Wiegand, Tanner; Surya, Kevin; Buyukyoruk, Murat; Vanderwood, Karl K.; Wilkinson, Royce A.; Wiedenheft, Blake

doi:10.2139/ssrn.3664367

Cited by 9 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The analysis of wastewater has been found to allow the detection of viruses and variants 18,19 and can therefore play a role in epidemiological surveillance. In the present work, the viability of wastewater-based surveillance in a region was assessed with regard to its reliability as a follow-up method and its possible use as a predictive tool www.nature.com/scientificreports/ to anticipate epidemiological dynamics.…”

Section: Discussionmentioning

confidence: 99%

“…This was found to be a useful source of information to track pandemic dynamics and characteristics. For instance, sequencing of the SARS-CoV-2 genome in wastewater can provide information concerning the circulation of variants in the target city or community 18,19 . In addition, several studies determined a correlation between SARS-CoV-2 RNA in wastewater and reported COVID-19 cases, which highlighted the potential application of sewage surveillance to study spatial and temporal variations in virus circulation in the population 20,21 .…”

mentioning

confidence: 99%

See 1 more Smart Citation

Assessing wastewater-based epidemiology for the prediction of SARS-CoV-2 incidence in Catalonia

Joseph-Duran

Serra-Compte

Sarrias

et al. 2022

Sci Rep

View full text Add to dashboard Cite

While wastewater-based epidemiology has proven a useful tool for epidemiological surveillance during the COVID-19 pandemic, few quantitative models comparing virus concentrations in wastewater samples and cumulative incidence have been established. In this work, a simple mathematical model relating virus concentration and cumulative incidence for full contagion waves was developed. The model was then used for short-term forecasting and compared to a local linear model. Both scenarios were tested using a dataset composed of samples from 32 wastewater treatment plants and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) incidence data covering the corresponding geographical areas during a 7-month period, including two contagion waves. A population-averaged dataset was also developed to model and predict the incidence over the full geography. Overall, the mathematical model based on wastewater data showed a good correlation with cumulative cases and allowed us to anticipate SARS-CoV-2 incidence in one week, which is of special relevance in situations where the epidemiological monitoring system cannot be fully implemented.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Assessing wastewater-based epidemiology for the prediction of SARS-CoV-2 incidence in Catalonia

Joseph-Duran

Serra-Compte

Sarrias

et al. 2022

Sci Rep

View full text Add to dashboard Cite

show abstract

Novel coronavirus disease (COVID-19): origin, transmission through the environment, health effects, and mitigation strategies—a review

Singh

Haq

2021

Environmental Sustainability

View full text Add to dashboard Cite

Graphical abstract The novel coronavirus disease (COVID-19), caused by severe acute respiratory coronavirus-2 (SARS-CoV-2), was first identified in China and subsequently spread globally, resulting in a severe pandemic, and officially declared a significant health emergency by World Health Organization (WHO). Genetic analysis of coronavirus isolated from bats, snakes, and Malay pangolins suggested that they could be intermediate hosts for SARS-CoV-2. The transfer of virus from person to person has been confirmed widely, while the actual source of origin is still unknown. COVID-19 is a highly contagious and infectious disease, and the worldwide transmission of coronavirus has intense effects on the lives of human beings. The spread of the virus is observed mainly through close contact with the infected person due to coughing, sniffing or indirectly through the contaminated surfaces. If people touch contaminated surfaces through their hands, mouth, nose, or eye, it enters the body and causes disease. Also, the virus may transmit through air droplets, water, food, fecal–oral transmission, etc. The infection of virus in human beings could be detected by direct symptoms, or different diagnostic tools are available to determine the viral load. Various safety measures are used to contain the virus, including disinfectants, antiviral drugs, vaccines, wearing masks, social distancing, etc. In the present review, we have focused on transmission of COVID-19 through air and wastewater as environmental transmission modes. We have also discussed the origin of the virus, its mode of action, host immune response, vulnerability, varying symptoms and diagnosis, prevention and control. Further, we have discussed the various treatment options to cope with this viral outbreak.

show abstract

Coronavirus in water media: Analysis, fate, disinfection and epidemiological applications

Buonerba

Corpuz

Ballesteros

et al. 2021

Journal of Hazardous Materials

View full text Add to dashboard Cite

Temporal Detection and Phylogenetic Assessment of SARS-CoV-2 in Municipal Wastewater

Cited by 9 publications

References 0 publications

Assessing wastewater-based epidemiology for the prediction of SARS-CoV-2 incidence in Catalonia

Assessing wastewater-based epidemiology for the prediction of SARS-CoV-2 incidence in Catalonia

Novel coronavirus disease (COVID-19): origin, transmission through the environment, health effects, and mitigation strategies—a review

Coronavirus in water media: Analysis, fate, disinfection and epidemiological applications

Contact Info

Product

Resources

About