Temperature variations as a source of uncertainty in medical fiber-coupled organic plastic scintillator dosimetry

Buranurak, Siritorn; Andersen, C.E.; Beierholm, Anders Ravnsborg; Lindvold, Lars René

doi:10.1016/j.radmeas.2013.01.049

Cited by 61 publications

(55 citation statements)

References 10 publications

(9 reference statements)

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“…For instance, their small size allows them to be placed inside narrow BT catheters inserted in the tumor region, and real-time monitoring of the detector response facilitates online error detection. The response of ISDs to absorbed dose in water is, in contrast to that of PSDs, dependent on the photon energy spectrum (Rogers 2009), while both ISD and PSD responses exhibit temperature dependence (Edmund and Andersen 2007, Beddar 2012, Wootton and Beddar 2013, Buranurak et al 2013). However, the energy and temperature dependences can be corrected for with fairly straightforward methods (Wootton and Beddar 2013, Reniers et al 2012).…”

Section: Introductionmentioning

confidence: 99%

Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy

Kertzscher

Beddar

2016

Phys. Med. Biol.

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We tested the potential of ruby inorganic scintillation detectors (ISDs) for use in brachytherapy and investigated various unwanted luminescence properties that may compromise their accuracy. The ISDs were composed of a ruby crystal coupled to a poly(methyl methacrylate) fiber-optic cable and a charge-coupled device camera. The ISD also included a long-pass filter that was sandwiched between the ruby crystal and the fiber-optic cable. The long-pass filter prevented the Cerenkov and fluorescence background light (stem signal) induced in the fiber-optic cable from striking the ruby crystal, which generates unwanted photoluminescence rather than the desired radioluminescence. The relative contributions of the radioluminescence signal and the stem signal were quantified by exposing the ruby detectors to a high-dose-rate brachytherapy source. The photoluminescence signal was quantified by irradiating the fiber-optic cable with the detector volume shielded. Other experiments addressed time-dependent luminescence properties and compared the ISDs to commonly used organic scintillator detectors (BCF-12, BCF-60). When the brachytherapy source dwelled 0.5 cm away from the fiber-optic cable, the unwanted photoluminescence was reduced from > 5% to < 1% of the total signal as long as the ISD incorporated the long-pass filter. The stem signal was suppressed with a band-pass filter and was < 3% as long as the source distance from the scintillator was < 7 cm. Some ruby crystals exhibited time-dependent luminescence properties that altered the ruby signal by > 5% within 10 s from the onset of irradiation and after the source had retracted. The ruby-based ISDs generated signals of up to 20 times that of BCF-12-based detectors. The study presents solutions to unwanted luminescence properties of ruby-based ISDs for high-dose-rate brachytherapy. An optic filter should be sandwiched between the ruby crystal and the fiber-optic cable to suppress the photoluminescence. Furthermore, we recommend avoiding ruby crystals that exhibit significant time-dependent luminescence.

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Section: Introductionmentioning

confidence: 99%

Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy

Kertzscher

Beddar

2016

Phys. Med. Biol.

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“…For the blue BCF-12 and the green BCF-60 (Saint-Gobain Crystals, Nemours Cedex, France) temperature coefficients of 20.15 6 0.01 and 20.55 6 0.04% K 21 , respectively, were observed. 53 These values show that careful consideration should be taken for clinical measurements. A group at the University of Texas MD Anderson Cancer Center (Houston, TX) has also reported significant differences between measurements from detectors inserted inside the patients and those in anthropomorphic phantoms, owing to the temperature dependence of the PSDs.…”

Section: 49mentioning

confidence: 99%

A review of recent advances in optical fibre sensors forin vivodosimetry during radiotherapy

O'Keeffe¹,

McCarthy²,

Woulfe³

et al. 2015

BJR

103

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This article presents an overview of the recent developments and requirements in radiotherapy dosimetry, with particular emphasis on the development of optical fibre dosemeters for radiotherapy applications, focusing particularly on in vivo applications. Optical fibres offer considerable advantages over conventional techniques for radiotherapy dosimetry, owing to their small size, immunity to electromagnetic interferences, and suitability for remote monitoring and multiplexing. The small dimensions of optical fibre-based dosemeters, together with being lightweight and flexible, mean that they are minimally invasive and thus particularly suited to in vivo dosimetry. This means that the sensor can be placed directly inside a patient, for example, for brachytherapy treatments, the optical fibres could be placed in the tumour itself or into nearby critical tissues requiring monitoring, via the same applicators or needles used for the treatment delivery thereby providing real-time dosimetric information. The article outlines the principal sensor design systems along with some of the main strengths and weaknesses associated with the development of these techniques. The successful demonstration of these sensors in a range of different clinical environments is also presented.

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“…9 Small dependence to temperature has also been reported with a small decrease of the plastic scintillator light output with increasing temperature. [10][11][12] This temperature dependence is an important consideration for a detector dedicated to in vivo dosimetry. Nevertheless, it becomes negligible in a temperature-controlled environment.…”

Section: Introductionmentioning

confidence: 99%

Characterization of a scintillating fibre detector for small animal imaging and irradiation dosimetry

Deroff

Frelin-Labalme

Ledoux

2017

BJR

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Objective: Small animal image-guided irradiators have recently been developed to mimic the delivery techniques of clinical radiotherapy. A dosemeter adapted to millimetric beams of medium-energy X-rays is then required. This work presents the characterization of a dosemeter prototype for this particular application. Methods: A scintillating optical fibre dosemeter (called DosiRat) has been implemented to perform real-time dose measurements with the dedicated small animal X-RAD® 225Cx (Precision X-Ray, Inc., North Branford, CT) irradiator. Its sensitivity, stem effect, stability, linearity and measurement precision were determined in large field conditions for three different beam qualities, consistent with small animal irradiation and imaging parameters. Results: DosiRat demonstrates good sensitivity and stability; excellent air kerma and air kerma rate linearity; and a good repeatability for air kerma rates .1 mGy s 21. The stem effect was found to be negligible. DosiRat showed limited precision for low air kerma rate measurements (,1 mGy s 21 ), typically for imaging protocols. A positive energy dependence was found that can be accounted for by calibrating the dosemeter at the needed beam qualities. Conclusion: The dosimetric performances of DosiRat are very promising. Extensive studies of DosiRat energy dependence are still required. Further developments will allow to reduce the dosemeter size to ensure millimetric beams dosimetry and perform small animal in vivo dosimetry. Advances in knowledge: Among existing point dosemeters, very few are dedicated to both medium-energy X-rays and millimetric beams. Our work demonstrated that scintillating fibre dosemeters are suitable and promising tools for real-time dose measurements in the small animal field of interest.

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Temperature variations as a source of uncertainty in medical fiber-coupled organic plastic scintillator dosimetry

Cited by 61 publications

References 10 publications

Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy

Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy

A review of recent advances in optical fibre sensors forin vivodosimetry during radiotherapy

Characterization of a scintillating fibre detector for small animal imaging and irradiation dosimetry

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Temperature variations as a source of uncertainty in medical fiber-coupled organic plastic scintillator dosimetry

Cited by 61 publications

References 10 publications

Ruby-based inorganic scintillation detectors for192Ir brachytherapy

Ruby-based inorganic scintillation detectors for192Ir brachytherapy

A review of recent advances in optical fibre sensors forin vivodosimetry during radiotherapy

Characterization of a scintillating fibre detector for small animal imaging and irradiation dosimetry

Contact Info

Product

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Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy

Ruby-based inorganic scintillation detectors for¹⁹²Ir brachytherapy