Temperature regulates the recognition activities of a galectin to pathogen and symbiont in the scleractinian coral Pocillopora damicornis

Wu, Yibo; Zhou, Zhi; Wang, Jun; Luo, Jian; Wang, Lingui; Zhang, Yidan

doi:10.1016/j.dci.2019.03.003

Cited by 11 publications

(15 citation statements)

References 42 publications

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“…Such hypotheses about the role of these galectin like structures in SARS-CoV-2 have been corroborated by findings on the administration of SARS-Cov-2 galectin like inhibitors, which reportedly decrease SARS-CoV-2 loads in patients ( Sethi, Sanam, Munagalasetty, Jayanthi, & Alvala, 2020 ). Remarkably, a relationship between temperature shifts and the activity of galectins in clearance of pathogens of “cauliflower” corals ( Pocillopora damicornis ), which is necessary to establish a healthy symbiosis with dinoflagellates, was recently established ( Wu et al, 2019 ). Lower temperatures were associated with increased pathogen survival.…”

Section: Discussionmentioning

confidence: 99%

The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality

Tomaszewski

Gürtler

Caetano-Anollés³

et al. 2022

Methods in Microbiology

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Section: Discussionmentioning

confidence: 99%

The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality

Tomaszewski

Gürtler

Caetano-Anollés³

et al. 2022

Methods in Microbiology

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“…In particular, galectin proteins with antimicrobial immunity functions were found in greater abundance in healthy coral symbioses ( Ricci et al, 2019 ). Remarkably, a recent study showed galectin functions of the scleractinian coral Pocillopora damicornis were dependent on temperature effects, establishing galectins as possible environmental sensors ( Wu et al, 2019 ). A cloned galectin that encoded a 293 amino acid-long protein harbouring a CRD and collagen-like N-terminal tail with signal peptide was able to recognize and agglutinate or stabilize coral pathogens and symbionts.…”

Section: Viral Genomic Make Up and Seasonalitymentioning

confidence: 99%

The seasonal behaviour of COVID-19 and its galectin-like culprit of the viral spike

Caetano-Anollés¹,

Hernandez

Mughal

et al. 2022

Covid-19: Biomedical Perspectives

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“…This process is probably important in reef‐building corals that live in a microbe‐rich environment (van Oppen & Blackall, 2019). The immune system of corals functions to both regulate commensal microbes (beneficial bacteria and the algal Symbiodiniaceae) as well as defend against pathogenic ones (Kvennefors et al, 2010; Mansfield & Gilmore, 2019; Mydlarz et al, 2006; Wu et al, 2019). Thus, the rapid evolution of immune transcript families indicates that these interactions may have played an important role in shaping the evolutionary history of these coral species.…”

Section: Discussionmentioning

confidence: 99%

“…as well as defend against pathogenic ones (Kvennefors et al, 2010;Mansfield & Gilmore, 2019;Mydlarz et al, 2006;Wu et al, 2019).…”

Section: Rapid Evolution Of Immunitymentioning

confidence: 99%

Adaptive variation in homologue number within transcript families promotes expression divergence in reef‐building coral

et al. 2022

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Gene expression, especially in multispecies experiments, is used to gain insight into the genetic basis of how organisms adapt and respond to changing environments. However, evolutionary processes that can influence gene expression patterns between species such as the presence of paralogues which arise from gene duplication events are rarely accounted for. Paralogous transcripts can alter the transcriptional output of a gene, and thus exclusion of these transcripts can obscure important biological differences between species. To address this issue, we investigated how differences in transcript family size are associated with divergent gene expression patterns in five species of Caribbean reef‐building corals. We demonstrate that transcript families that are rapidly evolving in terms of size have increased levels of expression divergence. Additionally, these rapidly evolving transcript families are enriched for multiple biological processes, with genes involved in the coral innate immune system demonstrating pronounced variation in homologue number between species. Overall, this investigation demonstrates the importance of incorporating paralogous transcripts when comparing gene expression across species by influencing both transcriptional output and the number of transcripts within biological processes. As this investigation was based on transcriptome assemblies, additional insights into the relationship between gene duplications and expression patterns will probably emergence once more genome assemblies are available for study.

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Temperature regulates the recognition activities of a galectin to pathogen and symbiont in the scleractinian coral Pocillopora damicornis

Cited by 11 publications

References 42 publications

The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality

The emergence of SARS-CoV-2 variants of concern in Australia by haplotype coalescence reveals a continental link to COVID-19 seasonality

The seasonal behaviour of COVID-19 and its galectin-like culprit of the viral spike

Adaptive variation in homologue number within transcript families promotes expression divergence in reef‐building coral

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