Telephonic survey and psychological aid for patients with somatic symptom disorders for the impact of lockdown and COVID-19 pandemic

Naskar, Chandrima; Grover, Sandeep; Sharma, Aman

doi:10.1177/0020764020954247

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Similarly, Italian health care workers exhibited increased irritability, a change in food habits, difficulty falling asleep, and muscle tension [ 135 ]. Similar cases have been reported from Brazil [ 136 ] and India [ 137 ]. Thus, strong support is emerging on the negative impact of the COVID-19 pandemic on the mental health issues such as anxiety, depression, anger, somatic symptoms, and sleep problems, particularly in health care workers.…”

Section: Peripheral Nervous System-associated Comorbiditiessupporting

confidence: 88%

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

et al. 2021

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The recent outbreak of SARS-CoV-2 infections that causes coronavirus-induced disease of 2019 (COVID-19) is the defining and unprecedented global health crisis of our time in both the scale and magnitude. Although the respiratory tract is the primary target of SARS-CoV-2, accumulating evidence suggests that the virus may also invade both the central nervous system (CNS) and the peripheral nervous system (PNS) leading to numerous neurological issues including some serious complications such as seizures, encephalitis, and loss of consciousness. Here, we present a comprehensive review of the currently known role of SARS-CoV-2 and identify all the neurological problems reported among the COVID-19 case reports throughout the world. The virus might gain entry into the CNS either through the trans-synaptic route via the olfactory neurons or through the damaged endothelium in the brain microvasculature using the ACE2 receptor potentiated by neuropilin-1 (NRP-1). The most critical of all symptoms appear to be the spontaneous loss of breathing in some COVID-19 patients. This might be indicative of a dysfunction within the cardiopulmonary regulatory centers in the brainstem. These pioneering studies, thus, lay a strong foundation for more in-depth basic and clinical research required to confirm the role of SARS-CoV-2 infection in neurodegeneration of critical brain regulatory centers. Keywords ACE1. ACE2. Brain. COVID-19. Coronavirus. Headache. Loss of consciousness. Loss of smell. Loss of taste. Neuropilin-1. Nervous system. SARS-CoV-2. Seizures. Stroke Abbreviations ACE2 Angiotensin-converting enzyme 2 ARDS Acute respiratory distress syndrome BBB Blood-brain barrier BNB Blood-nerve barrier BSCB Blood-spinal cord barriers CMAP Compound muscle action potential CNS Central nervous system CTSL Cathepsin L GBS Guillain-Barré syndrome

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Section: Peripheral Nervous System-associated Comorbiditiessupporting

confidence: 88%

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

et al. 2021

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“…Similarly, in Italy, health care workers were showing increased irritability, a change in food habits, insomnia, and muscle tension [ 43 ]. Similar cases have also been reported in India and Brazil [ 44 , 45 ].…”

Section: Peripheral Nervous System (Pns) Manifestationssupporting

confidence: 87%

COVID-19 associated nervous system manifestations

2022

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The novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a global pandemic in the last year. Along with major respiratory distress, a myriad of neurological manifestations was also reported to be associated with COVID-19 patients. These cases indicate that SARS-CoV-2 can be considered as an opportunistic pathogen of the brain. SARS-CoV-2 enters the brain through the olfactory bulb, retrograde axonal transport from peripheral nerve endings, or via hematogenous or lymphatic routes. Notably, COVID-19 infection can cause or even present with different neurological features including encephalopathy, impaired consciousness, confusion, agitation, seizure, ataxia, headache, anosmia, ageusia, neuropathies, and neurodegenerative diseases. In this paper, we provide a brief review of observed neurological manifestations associated with COVID-19.

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Telephonic survey and psychological aid for patients with somatic symptom disorders for the impact of lockdown and COVID-19 pandemic

Cited by 2 publications

References 5 publications

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

COVID-19 associated nervous system manifestations

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