Abstract:The feasibility of using the Internet for remote pathology consultation was examined. We assessed the diagnostic agreement between two groups of pathologists who independently evaluated histopathological cases exchanged by Internet electronic mail. The exchange was between two different workstations using readily available software not specifically developed for telemedicine. Data and images from 76 cases were transmitted to four pathologists. An average of 4.5 images per case were transmitted at compression r… Show more
“…Overall, diagnostic accuracy of static image telepathology has been reviewed numerous times in different studies and results range from 68-100%, with improving figures over the years [Della Mea et al, 1996;Weinberg et al, 1996;Halliday et al, 1997;Dunn et al, 1999;Williams et al, 2001;Cross et al, 2002;Nordrum et al, 2004]. Static image telepathology is an accessible technique that can also be used in developing countries.…”
Section: Low Accuracy Of Diagnosis In Telepathologymentioning
Malignant gonadal germ cell tumors, referred to as germ cell cancers (GCC), occur with increased frequency in individuals who have specific types of differences (disorders) of sex development (DSD). Recent population-based studies have identified new environmental and genetic risk factors that have led to a ‘genvironment' hypothesis, which may potentially be helpful in risk assessment in DSD-related GCC. In DSD, the malignancy risk is highly heterogeneous, but recent studies allow now to discriminate between high- and low-risk conditions. Gonadal biopsy is in some cases the best procedure of choice to assess the risk, and with the availability of immunohistochemical biomarkers [OCT3/4 (POU5F1), TSPY, SOX9, FOXL2 and KITLG (SCF)], a reliable classification of GCC and its precursors can be made. The opportunities in the field of virtual diagnostic pathology will be presented, having possibilities for rare diseases in general and DSD specifically. It is expected that the International DSD Registry will stimulate international collaborations, facilitating better diagnostic procedures as well as research.
“…Overall, diagnostic accuracy of static image telepathology has been reviewed numerous times in different studies and results range from 68-100%, with improving figures over the years [Della Mea et al, 1996;Weinberg et al, 1996;Halliday et al, 1997;Dunn et al, 1999;Williams et al, 2001;Cross et al, 2002;Nordrum et al, 2004]. Static image telepathology is an accessible technique that can also be used in developing countries.…”
Section: Low Accuracy Of Diagnosis In Telepathologymentioning
Malignant gonadal germ cell tumors, referred to as germ cell cancers (GCC), occur with increased frequency in individuals who have specific types of differences (disorders) of sex development (DSD). Recent population-based studies have identified new environmental and genetic risk factors that have led to a ‘genvironment' hypothesis, which may potentially be helpful in risk assessment in DSD-related GCC. In DSD, the malignancy risk is highly heterogeneous, but recent studies allow now to discriminate between high- and low-risk conditions. Gonadal biopsy is in some cases the best procedure of choice to assess the risk, and with the availability of immunohistochemical biomarkers [OCT3/4 (POU5F1), TSPY, SOX9, FOXL2 and KITLG (SCF)], a reliable classification of GCC and its precursors can be made. The opportunities in the field of virtual diagnostic pathology will be presented, having possibilities for rare diseases in general and DSD specifically. It is expected that the International DSD Registry will stimulate international collaborations, facilitating better diagnostic procedures as well as research.
“…The other form is the store-and-forward Tele-Medicine known as "pre-recorded" or "asynchronous" communication (Della et al, 1996;Fredriksen, Pettersen and Pedersen, 1997;Nordrum et al, 1998;Cross, 1996;Prednia, 1996;Kuntalp and Akar, 2004;Angonanakais et al, 2004). This type of application is less expensive, as there is no live interaction between the sender and receiver (Schwartz, et al, 2000;Sabale, 2003).…”
Section: Communication Service For Tele-cardiologymentioning
“…The diagnostic accuracy of histological diagnosis based on still images compared with glass slides from paraffin-embedded material has been reported to range from 52% to 96%. [4][5][6][7][8][9][10][11][12][13] The number of studies is limited, the available studies have varying designs and case composition, and few of these studies included second opinion cases. Thus, more studies are warranted.…”
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