It is shown that non-centrosymmetric materials with bulk second-order nonlinear susceptibility can be used to generate strongly antibunched radiation at an arbitrary wavelength, solely determined by the resonant behavior of suitably engineered coupled microcavities. The proposed scheme exploits the unconventional photon blockade of a coherent driving field at the input of a coupled cavity system, where one of the two cavities is engineered to resonate at both fundamental and second harmonic frequencies, respectively. Remarkably, the unconventional blockade mechanism occurs with reasonably low quality factors at both harmonics, and does not require a sharp doubly-resonant condition for the second cavity, thus proving its feasibility with current semiconductor technology. Introduction. There is currently pressing need for the development of integrated quantum technologies allowing for the generation and manipulation of quantum states of the electromagnetic radiation, with the ultimate goal of defining a photonic-based architecture for quantum information processing [1]. For interfacing with long distance infrastructures based on fiber-optics communication, state-of-art sources of quantum radiation have been lately developed at the typical telecommunication wavelengths, either based on heralding photons [2,3] or on artificial quantum emitters [4]. However, a source of quantum radiation that is not related to any resonant behavior of a quantum emitter, but can be engineered to operate at arbitrary wavelength and work at room temperature has not yet been realized. To this end, the single-photon blockade of a strongly nonlinear system can be exploited to convert a coherent radiation source of defined wavelength into antibunched photon streams [5], as recently done in coupled quantum dot-cavity systems [6,7], with potential implications for the realization of single-photon transistors [8] and interferometers [9].