Telaprevir Experience From Turkey

Kömür, Süheyla; Kurtaran, Behice; İnal, Ayşe Seza; Pullukçu, Hüsnü; Ulu, Aslıhan; Kuşçu, Ferit; Yamazhan, Tansu; Taşova, Yeşim; Aksu, Hasan Salih Zeki

doi:10.5812/hepatmon.25639

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…Benzer şekilde Kömür ve ark. (21) 'nın çalışmasında KVC oranları önceki aldıkları standart tedaviye cevaplarına bağlı olarak değişmemiştir.…”

Section: Discussionunclassified

Results of Boceprevir and Telaprevir Combination Therapy in Chronic Hepatitis C Patients in Nevşehir Province

Borcak¹,

Çağır²

2016

Ankem Derg

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ÖZET Kronik hepatit C infeksiyonu Anahtar sözcükler: Boceprevir, hepatit C infeksiyonu, proteaz inhibitörü, telaprevir SUMMARY Results of Boceprevir and Telaprevir Combination Therapy in Chronic Hepatitis C Patients in Nevşehir Province Chronic Hepatitis C infection is an important health problem in Turkey. The most frequently observed hepatitis C virus (HCV) genotype in Turkey is genotype 1b. Protease inhibitor antiviral agents boceprevir (BOC) and telaprevir (TVR) for HCV infection are one of the major advances in its medical treatment. The combination of BOC and TVR with pegylated interferonalpha and ribavirin (PegIFN/RBV) for the treatment of patients infected with HCV genotype 1 has caused significantly increased rates of sustained virologic response (SVR

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“…Benzer şekilde Kömür ve ark. (21) 'nın çalışmasında KVC oranları önceki aldıkları standart tedaviye cevaplarına bağlı olarak değişmemiştir.…”

Section: Discussionunclassified

Results of Boceprevir and Telaprevir Combination Therapy in Chronic Hepatitis C Patients in Nevşehir Province

Borcak¹,

Çağır²

2016

Ankem Derg

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“…12,13 Several preventable risk factors such as length of ICU stay, prior use of antibiotic, severity score at admission, and duration of catheterisation acts as a potential factors for development of CAUTI which should be identified among the patients admitted in ICU. 14,15 The aim of this research was to study the prevalence of CAUTI among the patients admitted in the adult ICU of a tertiary care hospital and to identify its potential risk factors and causative organisms.…”

Section: Introductionmentioning

confidence: 99%

Clinical significance of Catheter-Associated Urinary Tract Infection (CAUTI) in Intensive Care Units: Three Year Experience at a Single Centre

Basukala

Yadav

Chatterjee

et al. 2021

Med. J. Shree Birendra Hosp.

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Introduction: Catheter Acquired Urinary Tract Infection (CAUTI) is one of the most common Health Care Acquired Infections (HCAI); most of these infections are attributable to use of an indwelling urethral catheter. The aim of this study was to investigate patients with catheter-associated urinary tract infection over three years at a single hospital’s Intensive Care Unit (ICU) and to identify meaningful risk factors and causative organisms. Methods: A retrograde analysis was performed on patients with indwelling catheters in ICU of Armed Forces Medical College, Pune, India. CAUTI was defined as isolated bacterial growth of 100,000 colony-forming units or more either 48 hours after transfer to the ICU if a urinary catheter was placed before the transfer or 48 hours after insertion if the catheter was inserted in the ICU. Only the patients whose culture results were negative before ICU admission were included. Result: Among 350 samples collected in medical and surgical ICU, 38 patients (10.85%) had CAUTI. Using multivariate logistic regression analysis, the study showed that those with diabetes were 4.51 (p＜0.001) times likely to have occurrences of CAUTI than those without and also showed an increased incidence of CAUTI > 1.19 fold (p＜0.01) among patient with longer duration of an indwelling catheter. Conclusions: CAUTI is a preventable HCAI and thus the risk factors and causative organisms contributing to its development in the management of ICU patients must be considered to prevent the occurrence of UTIs in this setting.

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“…We have read with great interest the article entitled “Telaprevir experience from Turkey” by Komur et al recently ( 1 ).…”

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Telaprevir Experience From Turkey

Cited by 4 publications

References 15 publications

Results of Boceprevir and Telaprevir Combination Therapy in Chronic Hepatitis C Patients in Nevşehir Province

Results of Boceprevir and Telaprevir Combination Therapy in Chronic Hepatitis C Patients in Nevşehir Province

Clinical significance of Catheter-Associated Urinary Tract Infection (CAUTI) in Intensive Care Units: Three Year Experience at a Single Centre

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