Teichoic acid antibody test: its use in patients with coagulase-positive staphylococcal bacteremia

Occurrence of antibodies to teichoic acid in patients with diseases other than staphylococcal infection

“…In patients without S. aureus infection, TAA has most often been reported in patients with endocarditis or bacteraemia caused by streptococci or pneumococci, S. epidermidis, diphtheroids and E. coli (Crowder and White, 1972;Hoppes and White, 1975;Nagel et al, 1975;Larinkari et al, 1977;Leffell et al, 1978;Tuazon et al, 1978;Tenenbaum and Archer, 1980).…”

“…This is less likely because the ASta values were normal in eight of the 10 persons with TAA titres 2 8. On the other hand, it is known that in S. aureus bacteraemia positive TAA and ASta results often occur in different patients (Larinkari et al, 1977). One of the two patients with a slightly elevated ASta and a high TAA titre had atopic dermatitis, a condition in which elevated ASta values and TAA titres are likely to occur (Mustakallio, 1966;Larinkari, 1982~).…”

“…The teichoic acid antibody (TAA) test has proved valuable in the diagnosis of bacteraemic infections caused by Staphylococcus aureus (Larinkari et al, 1977;Tuazon et al, 1978;Wheat, Kohler and White, 1978;Bayer et al, 1980;Tenenbaum and Archer, 1980). Especially high TAA titres have been found in staphylococcal endocarditis and in other complicated staphylococcal infectibns with metastatic abscess formation (Crowder and White, 1972;Nagel et al, 1975;Tuazon and Sheagren, 1976;Tuazon et al, 1978;Wheat et al, 1978;Bayer et al, 1980;Tenenbaum and Archer, 1980).…”

Serum antibody to staphylococcal teichoic acid and α-haemolysin in dermatological patients

“…TAA measurement TAA was determined by the gel diffusion method (Ouchterlony) as described previously (Larinkari et al, 1977). Serial two-fold dilutions of sera were tested against the antigen, a i: 200 diluted sonicate of Staphylococcus aureus strain Copenhagen.…”

“…Comparisons have been made between TAA titres and antibody to staphylococcal a-haemolysin (ASta); the former was more often positive in patients with bacteraemic infections caused 54 U.Larinkari by Staphylococcus aureus (Larinkari et al, 1977), but in osteomyelitis patients, positive results were more often obtained by ASta assay than by TAA test (Larinkari, 1982). In general, TAA titres and ASta values are poorly correlated (Larinkari et al, 1977;Flandrois et al, 1979).…”