Integration of an organic photovoltaic (PV) with carbon-based supercapacitors (SCs) into a system for solar energy harvesting and storage is interesting for off-grid applications such as mobile electronics and sensor systems. Presented here is a conversion and control circuit (CC) on a flexible polyimide substrate in an integrated flexible energy harvesting and storage device compatible with roll-to-roll manufacturing (R2R). The CC is capable of PV max power-point tracking, DC-DC voltage boost of the PV output across a bank of four SCs, and charge balancing across the bank of SCs. This system is compared to a conventional direct connection between the PV and the SCs. More energy can be harvested from the PV and stored in the SC bank when using the CC to drive the PV at peak power, boost the output voltage, and balance it across serial connection of SCs. Finally, the CC, PV, and SCs are mounted to a 3D printed substrate and circuit which is used to power a wearable sensor. Due to these benefits and ability to be integrated with R2R, the presented CC provides a practical means of improving wearable solar energy harvesting and storage systems. In the flexible electronics literature, multiple publications demonstrated novel energy materials and devices, such as thin-film flexible photovoltaics (PVs)1-10 and carbon-based supercapacitors (SCs) [11][12][13][14][15][16][17][18] that are roll-to-roll (R2R) compatible. A few publications have further integrated a PV material with SCs to form an energy device capable of solar energy harvest and storage. 17,[19][20][21][22][23][24] Although simply connecting the devices without a conversion and control circuit (CC) that controls the flow of charge and the load impedance experienced by the PV can harvest and store energy, there are three problems that arise from this configuration: (i) the PV elements are operated inefficiently at suboptimal voltage-current conditions, far from the maximum-power point (MPP), (ii) undercharging the SCs due to low PV output voltage, and (iii) unbalanced charge storage across a bank of SCs with the risk of overcharging some while undercharging other SCs as well as a low usable combined capacity. These problems result in an inefficient and impractical energy device. In large PV systems, a CC typically mitigates these problems. However, such CCs use a discrete design with stiff bus bars or rigid circuit boards, which are incompatible with the flexible film design of the rest of the system. The lack of availability of a R2R-compatible CC has limited the realization of a R2R energy fabric for practical applications such as wearable sensors and the internet of things (IoT). 25 Many techniques have been developed to enable R2R-compatible packaging of CCs. Within the CC architecture, switching-mode DC-DC boost converters have been given considerable attention. For example, Z-folded flexible planar transformers have been developed that allow R2R production. 26 Planar geometries of flexible foils for use as low-profile inductors 27 and flip-chip flex-ci...