Technology Characterisation

Frieß, Johannes L.; Giese, Bernd; Gleich, Arnim von

doi:10.1007/978-3-030-38934-5_1

Cited by 1 publication

(3 citation statements)

References 51 publications

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“…Fischer et al, 2006 ). By investigating available scientific information in an early assessment, TC aims to identify possible hazards and exposure potential (Frieß et al, 2020 ; von Gleich, 2013 ). Moreover, it aims to pre‐estimate the nature and extent of uncertainty domains in advance.…”

Section: Technology Characterization Of Hegaamentioning

confidence: 99%

“…This is reminiscent of the Release of Insects carrying a Dominant Lethal allele (RIDL), which introduces a conditional viability, dependent on tetracycline. This dead switch, however, is encumbered with its own vulnerabilities (Benedict & Robinson, 2003 ; Evans et al, 2019 ; Frieß et al, 2020 ; Massonnet‐Bruneel et al, 2013 ; Phuc et al, 2007 ).…”

Section: Technology Characterization Of Hegaamentioning

confidence: 99%

“…However, gene transfer is strictly vertical and thus limited to the target species and, owing to the lethality of the GM trait, the intervention is self‐limiting. For a more thorough technological characterization of the RIDL technology, see Frieß et al ( 2020 ).…”

Section: Technology Characterization Of Hegaamentioning

confidence: 99%

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Insect allies—Assessment of a viral approach to plant genome editing

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Integr Envir Assess & Manag

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The Insect Allies program of the Defense Advanced Research Projects Agency has already sparked scientific debate concerning technology assessment-related issues, among which the most prevalent is that of dual use. Apart from the issues concerning peaceful applications, the technology also provides the blueprint for a potential bioweapon. However, the combination of a virus-induced genetic modification of crop plants in the field using genetically modified insect vectors poses a greater risk than the hitherto existing use of genetically modified organisms. The technology's great depth of intervention allows a number of sources for hazard and a tendency towards high exposure, but it is also encumbered with notable deficits in knowledge. These issues call for a thorough technology assessment. This article aims to provide an initial characterization from a technology assessment perspective, focusing on potential sources of risk for this novel invasive environmental biotechnology at an early stage of research and development.

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Section: Technology Characterization Of Hegaamentioning

confidence: 99%