2019
DOI: 10.1007/s00247-018-04338-5
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Technique, pitfalls, quality, radiation dose and findings of dynamic 4-dimensional computed tomography for airway imaging in infants and children

Abstract: This retrospective review of 33 children’s dynamic 4-dimensional (4-D) computed tomography (CT) images of the airways, performed using volume scanning on a 320-detector array without anaesthesia (free-breathing) and 1.4-s continuous scanning, was undertaken to report technique, pitfalls, quality, radiation doses and findings. Tracheobronchomalacia (airway diameter collapse >28%) was recorded. Age-matched routine chest CT scans and bronchograms acted as benchmarks for comparing effective dose. Pitfalls included… Show more

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Cited by 23 publications
(31 citation statements)
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“…The combination of 3D-CT bronchography with bronchoscopy has the advantage of demonstrating the airway distal to the stenosis, where it may be unsafe to advance the bronchoscope. Noticeably, without the use of sedation or anesthesia, paired images from a dynamic 4D-CT during physiological breathing are more sensitive to address bronchomalacia compared with bronchoscopy, avoiding underestimation of the disease extent or misdiagnosis of associated bronchomalacia as fixed stenosis ( 23 , 28 ). As for our case, although 3D-CT provided images of the abnormal carina and right lobar bronchus, limited recognition of type IIb PAS hindered us from obtaining detailed information regarding bronchial sites of stenosis and relationships between the airways and neighboring vascular structures.…”
Section: Discussionmentioning
confidence: 99%
“…The combination of 3D-CT bronchography with bronchoscopy has the advantage of demonstrating the airway distal to the stenosis, where it may be unsafe to advance the bronchoscope. Noticeably, without the use of sedation or anesthesia, paired images from a dynamic 4D-CT during physiological breathing are more sensitive to address bronchomalacia compared with bronchoscopy, avoiding underestimation of the disease extent or misdiagnosis of associated bronchomalacia as fixed stenosis ( 23 , 28 ). As for our case, although 3D-CT provided images of the abnormal carina and right lobar bronchus, limited recognition of type IIb PAS hindered us from obtaining detailed information regarding bronchial sites of stenosis and relationships between the airways and neighboring vascular structures.…”
Section: Discussionmentioning
confidence: 99%
“…Although advanced molecular imaging tools are not uniformly available in all countries, many developing countries are installing and using advanced imaging tools with increased frequency with imaging studies often performed at a substantially lower cost than many developed countries ( 112 ). Chest CT can be performed rapidly (seconds) with focused PET scans (3–5 minutes) without the need for sedation, even in young children, and with much lower radiation doses owing to improved CT technologies ( 4 , 113 ). Additionally, many molecular imaging tracers (PET, SPECT) currently under development for TB are rapidly excreted, which substantially decreases radiation exposure.…”
Section: Implementing Molecular Imaging: the Not-too-distant Futurementioning
confidence: 99%
“…Confrontando imágenes del final de la inspiración y del final de la espiración la TC logra establecer presencia, severidad y extensión de TM, con alta sensibilidad y especificidad (17). Las desventajas incluyen la exposición a radiación, la necesidad de anestesia general, particularmente en lactantes y preescolares pequeños, la cual puede distorsionar la vía aérea y afectar los cambios dinámicos de la misma (18,19). Sus ventajas incluyen ser un examen relativamente poco invasivo y sobre todo entregar valiosa información de parénquima pulmonar y mediastino, especialmente en estudios con contraste, definiendo compresiones externas cardiovasculares o por masas; por ello su rol es primordial en la caracterización de las TM secundarias y en la planificación preoperatoria de TM con indicación quirúrgica.…”
Section: Diagnósticounclassified