Technique for intraoperatory harvesting of adipose derived stem cells: towards cell treatment of recalcitrant ulcers

Abstract

Successful wound and ulcer repair remains a major biomedical challenge in the 21<sup>st</sup> Century. Innovative and alternative treatment options have been investigated over the last decade and stem cells application has been suggested as a possible novel therapy for regenerative medicine. In particular, stem cells derived from adipose tissue have been attracting a lot of attention in recent years as an alternative to the use of cells derived from bone marrow. This technical note describes the procedure introduced by Coleman for intraoperatory harvesting of adipose derived-stem-cells and proposes a rationale for using it in difficult wound healing and recalcitrant ulcers.