2005
DOI: 10.2460/javma.2005.226.1508
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Technique and outcome of mitral valve replacement in dogs

Abstract: Eight dogs with naturally occurring severe mitral regurgitation underwent mitral valve replacement with a mechanical valve prosthesis during cardiopulmonary bypass. Dogs received warfarin orally after surgery to maintain a prothrombin time-based international normalized ratio from 2.5 to 3.5. Seven dogs survived surgery. Left ventricular diastolic volume index decreased significantly from 206 +/- 91 mL/m2 before surgery to 121 +/- 47 mL/m2 after surgery. Left atrium-to-aorta ratio decreased significantly from … Show more

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Cited by 64 publications
(61 citation statements)
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“…Recent improvements in cardiopulmonary bypass techniques have enabled its use in small breed dogs (34,35). In the case of prosthetic valves, matching the size of the valve and conquering thrombosis is essential for long-term prognosis (36). Recently, successful techniques for mitral valve repair with annuloplasty and chordal replacement have been utilized, which enables long-term survival for severe MMVD patients (37).…”
Section: Surgical Management Of Mmvdmentioning
confidence: 99%
“…Recent improvements in cardiopulmonary bypass techniques have enabled its use in small breed dogs (34,35). In the case of prosthetic valves, matching the size of the valve and conquering thrombosis is essential for long-term prognosis (36). Recently, successful techniques for mitral valve repair with annuloplasty and chordal replacement have been utilized, which enables long-term survival for severe MMVD patients (37).…”
Section: Surgical Management Of Mmvdmentioning
confidence: 99%
“…Esse é um acidente comum de ocorrer devido à característica do endotélio e à inexperiência do cirurgião, tendendo à não reocorrência conforme maior a prática, como observado também em outro experimento 8 . A hemorragia decorrente da ruptura da aorta no animal 1 foi solucionada rapidamente com a sutura da mesma, porém impossibilitou a efetivação da linha arterial através da aorta, procedendo-se, então, à técnica com a canulação da artéria femoral, assim como realizado em outros experimentos [9][10][11] , mantendo-se o animal durante 30 minutos em CEC e uma hora de reperfusão pós-CEC, assim como os demais animais, os quais não sofreram acidentes trans-cirúrgicos durante a efetivação da técnica, que foi realizada com destreza.…”
Section: Resultsunclassified
“…In a median sternotomy or a right lateral thoracotomy, venous catheters were generally inserted through the right atrium into a cranial vena cava and a caudal vena cava to drain the blood from the heart to CPB system [21,23,29]. But in this study, we performed MVR with a left lateral thoracotomy because the approach to the mitral valve via a left atrium incision was very easy.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, bioprosthetic valves have limited durability but have low thrombogenicity and do not require long-term anticoagulation therapy [1,22]. In dogs, mechanical valve replacement is so difficult to obtain a long-term survival rate because of a prosthetic valve thrombosis [21,24]. Therefore, bioprosthetic valves are recommended for dogs, and porcine bioprosthetic valves cross-linked with glutaraldehyde and polyepoxy compounds were newly developed for MVR.…”
mentioning
confidence: 99%