Technetium-99m Bone Scan and Panoramic Radiography in Detection of Bone Invasion by Oral Carcinoma

Jamdade, Anshuman; John, Ani

doi:10.7860/jcdr/2014/8429.4378

Cited by 2 publications

(2 citation statements)

References 25 publications

(45 reference statements)

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“…Generally, oral carcinoma can be detected via many diagnosed tests and modalities, such as bone scan [ 7 ], computed tomography (CT) [ 8 ], magnetic resonance imaging (MRI) [ 9 ], and ultrasonography [ 10 ]. However, some cases are still suffering from poor prognosis and low detection and 5-year survival rates.…”

Section: Introductionmentioning

confidence: 99%

Utilization of gold nanoparticles for the detection of squamous cell carcinoma of the tongue based on laser-induced fluorescence and diffuse reflectance characteristics: an in vitro study

et al. 2022

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Squamous cell carcinoma is a very common type of oral cancer that affects the health of people with an unacceptably high mortality rate attributed to the difficulties in detecting the disease at an early stage. Therefore, effective techniques for early diagnosis and effective therapy of oral cancer are necessary. In the present study, we exploit the ability of gold nanoparticles (AuNPs) to undergo coupled surface plasmon resonance when closely spaced to improve diagnosing squamous cell carcinoma of the tongue. The prepared AuNPs are characterized by UV–VIS spectroscopy, dynamic light scattering, Fourier transform infrared spectroscopy, and transmission electron microscopy. The size of the prepared AuNPs is 12 ± 2 nm with narrow size distributions and exhibited high stability with a zeta potential of − 16.5 mV. The light fluorescence of the normal and cancer cells is recorded before and after NP addition using a spectrometer upon excitation by 405-nm laser irradiation. Furthermore, the light reflectance of the examined samples is measured at different laser wavelengths (red to NIR region). The obtained results show that the cancer cells mixed with AuNPs produce a higher fluorescence peak at 489.2 nm than the cancer cells without AuNPs. Moreover, the optical diffuse reflectance analyses reveal that the addition of AuNPs enhances cancer detection especially at the 635-nm irradiation with sensitivity (94%), specificity (87%), and overall accuracy (91%).

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Section: Introductionmentioning

confidence: 99%

Utilization of gold nanoparticles for the detection of squamous cell carcinoma of the tongue based on laser-induced fluorescence and diffuse reflectance characteristics: an in vitro study

et al. 2022

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“…The test has been found to offer a good balance between its reasonable accuracy and relatively low cost and radiation dose compared with other imaging modalities such as FDG PET/CT and, thus, is commonly used as the initial screening test for bone metastasis [9,10]. BS has been found to have sensitivity and specificity ranging from 55% to 88% and 50% to 98%, respectively for diagnosis of bone metastasis and local bone invasion from HNCs [9,[11][12][13][14]. Previous studies have examined positivity yield of BS in patients with HNCs and reported conflicting results.…”

Section: Introductionmentioning

confidence: 99%

Multiple Regression Analysis of Predictors of Bone Scintigraphy Positivity in Patients with Head and Neck Cancers

Theerakulpisut

Wongsurawat

Supakalin

et al. 2017

Nucl Med Mol Imaging

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In contrast to several studies, bone metastasis as detected by BS was found in a relatively high proportion of patients with HNCs. Independent predictors of BS positivity include the age of less than 45 years, tumor site at the nasopharynx, and the presence of extraskeletal distant metastasis. BS could be useful in patients with these characteristics which enhance the pretest probability of bone metastasis.

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Technetium-99m Bone Scan and Panoramic Radiography in Detection of Bone Invasion by Oral Carcinoma

Cited by 2 publications

References 25 publications

Utilization of gold nanoparticles for the detection of squamous cell carcinoma of the tongue based on laser-induced fluorescence and diffuse reflectance characteristics: an in vitro study

Utilization of gold nanoparticles for the detection of squamous cell carcinoma of the tongue based on laser-induced fluorescence and diffuse reflectance characteristics: an in vitro study

Multiple Regression Analysis of Predictors of Bone Scintigraphy Positivity in Patients with Head and Neck Cancers

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