Tea consumption and cognitive impairment and decline in older Chinese adults

Ng, Tze‐Pin; Feng, Lei; Niti, Mathew; Kua, Ee‐Heok; Yap, Keng Bee

doi:10.1093/ajcn/88.1.224

Cited by 210 publications

(197 citation statements)

References 31 publications

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“…It has been found that green tea consumption is significantly associated with a lower risk of mortality due to stroke [29] and pneumonia [30] and imparts a lower risk of cognitive impairment [31], depression [32], and psychological distress [33]. These results have been confirmed by other researchers [34][35][36][37]. In addition, other epidemiologic studies have indicated that green tea consumption is associated with a lower risk of osteoporosis [38,39], and randomized placebo-controlled trials have indicated that green tea is effective in lowering cardiovascular risk factors [40,41].…”

Section: The Health Effects Of Green Teasupporting

confidence: 61%

Cancer Chemoprevention by Dietary Polyphenols

Aly¹,

Mahmoud²

2013

Carcinogenesis

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Section: The Health Effects Of Green Teasupporting

confidence: 61%

Cancer Chemoprevention by Dietary Polyphenols

Aly¹,

Mahmoud²

2013

Carcinogenesis

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“…In addition, two studies had combined coffee and tea drinking as caffeine intake and indicated some positive effects on cognitive functioning [15,16]. For tea consumption, only one study has found positive effects against cognitive decline [19].…”

Section: Discussionmentioning

confidence: 99%

“…In the Singapore Longitudinal Ageing Studies (SLAS) cohort among 55 years old persons, regular tea drinking was associated with a reduced risk of cognitive decline during a 1-2 year period [19].…”

Section: Previous Longitudinal Studiesmentioning

confidence: 99%

Caffeine as a Protective Factor in Dementia and Alzheimer's Disease

Eskelinen

Kivipelto

2010

JAD

218

142

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Abstract. Caffeine has well-known short-term stimulating effects on central nervous system, but the long-term impacts on cognition have been less clear. Dementia and Alzheimer's disease (AD) are rapidly increasing public health problems in ageing populations and at the moment curative treatment is lacking. Thus, the putative protective effects of caffeine against dementia/AD are of great interest. Here, we discuss findings from the longitudinal epidemiological studies about caffeine/coffee/tea and dementia/AD/cognitive functioning with a special emphasis on our recent results from the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study. The findings of the previous studies are somewhat inconsistent, but most studies (3 out of 5) support coffee's favorable effects against cognitive decline, dementia or AD. In addition, two studies had combined coffee and tea drinking and indicated some positive effects on cognitive functioning. For tea drinking, protective effects against cognitive decline/dementia are still less evident. In the CAIDE study, coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life. In conclusion, coffee drinking may be associated with a decreased risk of dementia/AD. This may be mediated by caffeine and/or other mechanisms like antioxidant capacity and increased insulin sensitivity. This finding might open possibilities for prevention or postponing the onset of dementia/AD.

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“…Comparable results were obtained in another study including 2501 Chinese aged 455 years. 5 The authors showed by similar methods that the intake of green tea is significantly related to a lower prevalence of cognitive impairment. Taken together, there is preliminary evidence in the literature that the intake of green tea or its main ingredients have a positive impact on cognitive functions.…”

Section: Introductionmentioning

confidence: 99%

Neural effects of green tea extract on dorsolateral prefrontal cortex

et al. 2012

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BACKGROUND/OBJECTIVES: Green tea is being recognized as a beverage with potential benefits for human health and cognitive functions. In vivo studies provide preliminary evidence that green tea intake may have a positive role in improving effects on cognitive functions. We aimed to examine the neural effects of green tea extract on brain activation in humans. SUBJECTS/METHODS: Functional magnetic resonance imaging was recorded while 12 healthy volunteers performed a working memory task following administration of 250 or 500 ml of a milk whey based green tea containing soft drink or milk whey based soft drink without green tea as control in a double-blind, controlled repeated measures within-subject design with counterbalanced order of substance administration. A whole-brain analysis with a cluster-level threshold of Po0.001 (unadjusted) was followed by an a priori-defined region of interest (ROI) analysis of the dorsolateral prefrontal cortex (DLPFC) including a cluster-level threshold of Po0.05 and family-wise error (FWE) adjustment for multiple comparisons. RESULTS: Whole-brain analyses revealed no significant effects after correction for multiple comparisons (FWE Po0.05). Using a ROI approach, green tea extract increased activation in the DLPFC relative to a control condition (FWE Po0.001). This neural effect was related to green tea dosage. Green tea extract was not associated with any significant attenuation in regional activation relative to control condition. CONCLUSIONS: These data suggest that green tea extract may modulate brain activity in the DLPFC, a key area that mediates working memory processing in the human brain. Moreover, this is the first neuroimaging study implicating that functional neuroimaging methods provide a means of examining how green tea extract acts on the brain.

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Tea consumption and cognitive impairment and decline in older Chinese adults

Abstract: Regular tea consumption was associated with lower risks of cognitive impairment and decline.

Cited by 210 publications

References 31 publications

Cancer Chemoprevention by Dietary Polyphenols

Cancer Chemoprevention by Dietary Polyphenols

Caffeine as a Protective Factor in Dementia and Alzheimer's Disease

Neural effects of green tea extract on dorsolateral prefrontal cortex

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