Tea and its phytochemicals: Hidden health benefits &amp; modulation of signaling cascade by phytochemicals

Bag, Sagar; Mondal, Anupam; Majumder, Anusha; Banik, Avishek

doi:10.1016/j.foodchem.2021.131098

Cited by 74 publications

(48 citation statements)

References 94 publications

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“…They are ubiquitously found in plant photosynthesizing cells and are commonly present in seeds, roots, flowers, vegetables, honey, fruits, stems, nuts, wine, propolis, and tea (Panche et al 2016 ). Having medicinal properties, they play a vital role in effective medical treatments (Bag et al 2022b ). Most of the flavonoids, if they are not substituted, are very poorly water-soluble (Kumar and Pandey 2013 ).…”

Section: Flavonoidsmentioning

confidence: 99%

“…Nowadays, they are also regarded as an essential component in a diverse array of medicinal, pharmaceutical nutraceutical, and cosmetic applications (Tohge et al 2017 ; Bag et al 2022a ). This is due to their anti-mutagenic, anti-oxidative, anti-carcinogenic and anti-inflammatory properties combined with their ability to modulate essential cellular enzymatic mechanisms (Panche et al 2016 ; Xiao 2017 ; Bag et al 2022b ).…”

Section: Introductionmentioning

confidence: 99%

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Flavonoid mediated selective cross-talk between plants and beneficial soil microbiome

et al. 2022

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Plants generate a wide variety of organic components during their different growth phases. The majority of those compounds have been classified as primary and secondary metabolites. Secondary metabolites are essential in plants’ adaptation to new changing environments and in managing several biotic and abiotic stress. It also invests some of its photosynthesized carbon as secondary metabolites to establish a mutual relationship with soil microorganisms in that specific niche. As soil harbors both pathogenic and beneficial microorganisms, it is essential to identify some specific metabolites that can discriminate beneficial and pathogenic ones. Thus, a detailed understanding of metabolite’s architectures that interact with beneficial microorganisms could open a new horizon of ecology and agricultural research. Flavonoids are used as classic examples of secondary metabolites in this study to demonstrate recent developments in understanding and realizing how these valuable metabolites can be controlled at different levels. Most of the research was focused on plant flavonoids, which shield the host plant against competitors or predators, as well as having other ecological implications. Thus, in the present review, our goal is to cover a wide range of functional and signalling activities of secondary metabolites especially, flavonoids mediated selective cross-talk between plant and its beneficial soil microbiome. Here, we have summarized recent advances in understanding the interactions between plant species and their rhizosphere microbiomes through root exudates (flavonoids), with a focus on how these exudates facilitate rhizospheric associations. Supplementary Information The online version contains supplementary material available at 10.1007/s11101-022-09806-3.

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Section: Flavonoidsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Flavonoid mediated selective cross-talk between plants and beneficial soil microbiome

et al. 2022

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“…Tea, processed from the leaves of Camellia sinensis, is one of the most widely consumed beverages worldwide. This drink is characterized by high levels of an antioxidant that has been shown to prevent different types of metabolic syndromes, cardiovascular diseases, obesity, and type 2 diabetes (Bag et al, 2022). Huang et al indicated that consumption of Pu-erh tea significantly increased the content of fecal conjugated BAs by decreasing the BSH activity, which was linked to a reduction in the levels of Lactobacillus, Bacillus, Streptococcus, and Lactococcus, resulting in the inhibition of intestinal FXR-FGF15 activation.…”

Section: Teamentioning

confidence: 99%

Section: Natural Plants Regulate the Interplay Between Gm And Bas In ...mentioning

confidence: 99%

Therapeutic Potential of Natural Plants Against Non-Alcoholic Fatty Liver Disease: Targeting the Interplay Between Gut Microbiota and Bile Acids

Sun

Xin

et al. 2022

Front. Cell. Infect. Microbiol.

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Non-alcoholic fatty liver disease (NAFLD) remains a common disease with a significant health and economic burden worldwide. The gut microbiota (GM) and bile acids (BAs), which play important roles in the gut-liver axis, have been confirmed to jointly participate in the development of NAFLD. GM not only regulate bile acids’ synthesis, transport, and reabsorption by regulating other metabolites (such as trimetlyl amine oxide, butyrate), but also regulate dehydrogenation, dehydroxylation and desulfurization of bile acids. Meanwhile, disordered bile acids influence the gut microbiota mainly through promoting the bacterial death and lowering the microbial diversity. Although weight loss and lifestyle changes are effective in the treatment of NAFLD, the acceptability and compliance of patients are poor. Recently, increasing natural plants and their active ingredients have been proved to alleviate NAFLD by modulating the joint action of gut microbiota and bile acids, and considered to be promising potential candidates. In this review, we discuss the efficacy of natural plants in treating NAFLD in the context of their regulation of the complex interplay between the gut microbiota and bile acids, the crosstalk of which has been shown to significantly promote the progression of NAFLD. Herein, we summarize the prior work on this topic and further suggest future research directions in the field.

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“…The polyphenol group not only includes the catechins, but also harbours several other members, such as the flavanols, their glycosides, and the three types of flavonoids. ( Wang et al, 2019 , Bag et al, 2022a ). That oxidative stress and reactive oxygen species trigger the formation of flavonoids in plants, explains why flavonoids can serve the dual purpose of inhibiting ROS production and provide protection to resist damage caused by UV radiation.…”

Section: Introductionmentioning

confidence: 99%

Virtual screening and docking analysis of novel ligands for selective enhancement of tea (Camellia sinensis) flavonoids

et al. 2022

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Tea and its phytochemicals: Hidden health benefits & modulation of signaling cascade by phytochemicals

Cited by 74 publications

References 94 publications

Flavonoid mediated selective cross-talk between plants and beneficial soil microbiome

Flavonoid mediated selective cross-talk between plants and beneficial soil microbiome

Therapeutic Potential of Natural Plants Against Non-Alcoholic Fatty Liver Disease: Targeting the Interplay Between Gut Microbiota and Bile Acids

Virtual screening and docking analysis of novel ligands for selective enhancement of tea (Camellia sinensis) flavonoids

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