TCT-690 Incremental Age-related 1-year MACCE after Acute Myocardial Infarction in the drug-eluting stent era (from KAMIR-NIH registry)

Kim, Dae‐Won; Kim, Dong‐Bin; Hong, Keepyung; Kim, Sung-Mi; Kim, Kyun Young; Her, Sung-Ho; Park, Ha-Wook; Kim, Jee Hyuk; Lee, Myun Hee; Bu, SeongHyeon; Hwang, Byung‐Hee

doi:10.1016/j.jacc.2018.08.1904

Cited by 3 publications

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“…10 papers eventually met all inclusion criteria [8][9][10][11][12][13][14][15][16][17]. The other 352 articles were excluded due to duplication, article types, irrelevant studies, no control groups, incomplete data or comparisons.…”

Section: Search Resultsmentioning

confidence: 99%

Bioresorbable vascular stents and drug-eluting stents in treatment of coronary heart disease: a meta-analysis

Ni¹,

Chen²,

Luo³

et al. 2020

J Cardiothorac Surg

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Objective: To compare the efficacy and safety of bioresorbable vascular stents (BVS) and drug-eluting stents (DES) in coronary heart disease. Methods: The full text of clinical studies involving BVS and DES was retrieved in PubMed, Springer, EMBASE, Wiley-Blackwell, and Chinese Journal Full-text Database. Review Manager 5.3 was used for meta-analysis to evaluate the risk of target lesion failure, stent thrombosis and cardiac death in BVS and DES. Results: Finally, 10 studies with 6383 patients were included in the meta-analysis. Compared with DES group, BVS group had significantly increased risk of target lesion failure (OR = 1.46, 95%CI 1.20-1.79, P = 0.0002; P Heterogeneity = 0.68, I 2 = 0%), stent thrombosis (OR = 2.70, 95%CI 1.57-4.66, P = 0.0003; P Heterogeneity = 1.00, I 2 = 0%) and cardiac death (OR = 2.19, 95%CI 1.17-4.07, P = 0.01; P Heterogeneity = 0.93, I 2 = 0%). Conclusion: This study shows that DES is a safer treatment than BVS for coronary revascularization.

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Section: Search Resultsmentioning

confidence: 99%

Bioresorbable vascular stents and drug-eluting stents in treatment of coronary heart disease: a meta-analysis

Ni¹,

Chen²,

Luo³

et al. 2020

J Cardiothorac Surg

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“…The number of individuals who develop HF after AMI undergoing PCI increases with age [ 22 ]. In an observational study of elderly patients with first MI, 75% of survivors developed HF in the subsequent 5 years [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Influencing factors and prognostic value of left ventricular systolic dysfunction in patients with complete occlusion of the left anterior descending artery reperfused by primary percutaneous coronary intervention

Jing

Guo

et al. 2023

BMC Cardiovasc Disord

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Background The aim of this study was to perform a retrospective analysis of patients with acute anterior wall ST-segment elevation myocardial infarction (AAW-STEMI) whose left anterior descending (LAD) artery was completely occluded and reperfused by primary percutaneous coronary intervention (PPCI) and to determine the influencing factors and prognostic value of left ventricular systolic dysfunction (LVSD) in the acute phase of acute myocardial infarction (AMI). Methods A total of 304 patients with AAW-STEMI were selected. The selected patients were divided into two groups: the preserved left ventricular ejection fraction (pLVEF) group (LVEF ≥ 50%, n = 185) and the reduced left ventricular ejection fraction (rLVEF) group (LVEF < 50%, n = 119). The influencing factors of LVSD and their predictive value for LVSD were analyzed. Patients were followed up by examining outpatient records and via telephone. The predictive value of LVSD for the cardiovascular mortality of patients with AAW-STEMI was analyzed. Results Age, heart rate (HR) at admission, number of ST-segment elevation leads (STELs), peak creatine kinase (CK) and symptom to wire-crossing (STW) time were independent risk factors for LVSD (P < 0.05). The receiver operating characteristic (ROC) analysis showed that the peak CK had the strongest predictive value for LVSD, with an area under the curve (AUC) of 0.742 (CI, 0.687 to 0.797) as the outcome. At a median follow-up of 47 months (interquartile range, 27 to 64 months), the Kaplan‒Meier survival curves up to 6-year follow-up revealed a total of 8 patients succumbed to cardiovascular disease, with 7 (6.54%) in the rLVEF group and 1 (0.56%) in the pLVEF group, respectively (hazard ratio: 12.11, [P = 0.02]). Univariate and multivariate Cox proportional hazards regression analysis demonstrated that rLVEF was an independent risk predictor of cardiovascular death in patients with AAW-STEMI discharged after PPCI (P < 0.01). Conclusions Age, HR at admission, number of STELs, peak CK, and STW time may be used to identify patients with a high risk of heart failure (HF) in a timely manner and initiate early standard therapy for incident LVSD in the acute phase of AAW-STEMI reperfused by PPCI. A trend toward increased cardiovascular mortality at follow-up was significantly linked to LVSD.

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“…The number of individuals who develop HF after AMI undergoing PCI increases with age [12]. In an observational study of elderly patients with rst MI, 75% of survivors developed HF in the subsequent 5 years [13].…”

Section: Agementioning

confidence: 99%

Influencing factors and prognostic value of left ventricular systolic dysfunction in patients with complete occlusion of the left anterior descending artery reperfused by primary percutaneous coronary intervention

Jing

Lu²,

Guo³

et al. 2023

Preprint

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Background: The aim of this study was to perform a retrospective analysis of patients with acute anterior wall ST-segment elevation myocardial infarction (AAW-STEMI) whose left anterior descending (LAD) artery was completely occluded and reperfused by primary percutaneous coronary intervention (PPCI) and to determine the influencing factors and prognostic value of left ventricular systolic dysfunction (LVSD) in the acute phase of acute myocardial infarction (AMI). Methods: A total of 304 patients with AAW-STEMI were selected. The selected patients were divided into two groups: the preserved left ventricular ejection fraction (pLVEF) group (LVEF≥50%, n=185) and the reduced left ventricular ejection fraction (rLVEF) group (LVEF<50%, n=119). The influencing factors of LVSD and their predictive value for LVSD were analyzed. Patients were followed up (median follow-up: 47 months [interquartile range: 27 to 64 months]) by examining outpatient records and via telephone. The predictive value of LVSD for the survival of patients with AAW-STEMI was analyzed. Results: Age, heart rate (HR) at admission, number of ST-segment elevation leads (STELs), peak creatine kinase (CK) and symptom to wire-crossing (STW) time were independent risk factors for LVSD. Peak CK had the strongest predictive value for LVSD. LVSD is an independent adverse factor for long-term prognosis in patients with AAW-STEMI discharged after PPCI. Conclusions: Age, HR at admission, number of STELs, peak CK, and STW time may be used to identify patients with a high risk of heart failure (HF) in a timely manner and initiate early standard therapy for patients with AAW-STEMI whose LAD artery was completely occluded and reperfused by PPCI. Incident LVSD in the acute phase after AAW-STEMI was significantly associated with a trend toward increased mortality at follow-up.

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TCT-690 Incremental Age-related 1-year MACCE after Acute Myocardial Infarction in the drug-eluting stent era (from KAMIR-NIH registry)

Cited by 3 publications

References 0 publications

Bioresorbable vascular stents and drug-eluting stents in treatment of coronary heart disease: a meta-analysis

Bioresorbable vascular stents and drug-eluting stents in treatment of coronary heart disease: a meta-analysis

Influencing factors and prognostic value of left ventricular systolic dysfunction in patients with complete occlusion of the left anterior descending artery reperfused by primary percutaneous coronary intervention

Influencing factors and prognostic value of left ventricular systolic dysfunction in patients with complete occlusion of the left anterior descending artery reperfused by primary percutaneous coronary intervention

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