TCP Genes and the Orchestration of Plant Architecture

Carrara, Scott; Dornelas, Marcelo Carnier

doi:10.1007/s12042-020-09274-z

Cited by 8 publications

(7 citation statements)

References 84 publications

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“…A growing number of studies have revealed that protein–protein interactions between members from different TF families play crucial roles in regulating metabolic or developmental pathways at the transcriptional level (Bemer et al., 2017). The TCP family contains 24 members in Arabidopsis, many of which have been shown to interact with TFs from other families (Bemer et al., 2017; Carrara & Dornelas, 2020), possibly as a means to integrate into different regulatory networks. A search for TFs capable of interacting with Arabidopsis class I TCPs led us to the identification of GLK1, a TF from the GARP superfamily (Fitter et al., 2002), as an interacting partner of several class I TCPs.…”

Section: Discussionmentioning

confidence: 99%

TCP15 interacts with GOLDEN2‐LIKE 1 to control cotyledon opening in Arabidopsis

et al. 2022

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After germination, exposure to light promotes the opening and expansion of the cotyledons and the development of the photosynthetic apparatus in a process called de-etiolation. This process is crucial for seedling establishment and photoautotrophic growth. TEOSINTE BRANCHED 1, CYCLOIDEA, and PROLIFERATING CELL FACTORS (TCP) transcription factors are important developmental regulators of plant responses to internal and external signals that are grouped into two main classes. In this study, we identified GOLDEN2-LIKE 1 (GLK1), a key transcriptional regulator of photomorphogenesis, as a protein partner of class I TCPs during light-induced cotyledon opening and expansion in Arabidopsis. The class I TCP TCP15 and GLK1 are mutually required for cotyledon opening and the induction of SAUR and EXPANSIN genes, involved in cell expansion. TCP15 also participates in the expression of photosynthesis-associated genes regulated by GLK1, like LHCB1.4 and LHCB2.2. Furthermore, GLK1 and TCP15 bind to the same promoter regions of different target genes containing either GLK or TCP binding motifs and binding of TCP15 is affected in a GLK1deficient background, suggesting that a complex between TCP15 and GLK1 participates in the induction of these genes. We postulate that GLK1 helps to recruit TCP15 for the modulation of cell expansion genes in cotyledons and that the functional interaction between these transcription factors may serve to coordinate the expression of cell expansion genes with that of genes involved in the development of the photosynthetic apparatus.

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Section: Discussionmentioning

confidence: 99%

TCP15 interacts with GOLDEN2‐LIKE 1 to control cotyledon opening in Arabidopsis

et al. 2022

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“…Although at first TCPs were known as modulators of cell elongation and division processes, today we know that they are involved in a wide range of biological processes throughout the entire life of plants, acting as crucial regulators of responses to internal and external signals through the recruitment of other proteins and the modulation of hormonal signaling pathways [ 16 , 40 ]. The TCPs from class II have been studied in several species and various reviews have been recently published [ 41 , 42 , 43 , 44 ], whereas class I TCPs were mainly characterized in Arabidopsis thaliana . In this review, we will examine the roles of class I TCPs in plant growth and development, as well as the modulation of their activity through interaction with other proteins and redox interconversions, proteolytic processing, or intra- or intercellular movement.…”

Section: Introductionmentioning

confidence: 99%

Physiological Roles and Mechanisms of Action of Class I TCP Transcription Factors

Viola

Alem

Jure

et al. 2023

IJMS

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TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTOR 1 and 2 (TCP) proteins constitute a plant-specific transcription factors family exerting effects on multiple aspects of plant development, such as germination, embryogenesis, leaf and flower morphogenesis, and pollen development, through the recruitment of other factors and the modulation of different hormonal pathways. They are divided into two main classes, I and II. This review focuses on the function and regulation of class I TCP proteins (TCPs). We describe the role of class I TCPs in cell growth and proliferation and summarize recent progresses in understanding the function of class I TCPs in diverse developmental processes, defense, and abiotic stress responses. In addition, their function in redox signaling and the interplay between class I TCPs and proteins involved in immunity and transcriptional and posttranslational regulation is discussed.

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“…The protein structural analysis of the bHLH TFs has shown that the TCP domain is characterized by a basic residue-rich region forming a typical fold of 3 short β -strands (β1, β2, and β3) and two consecutive α-helices (α-1 and α-2) ( Sun et al, 2020 ). However, the TCP domain is different to the bHLH domain ( Carrara and Dornelas, 2021 ). Recent demonstrations have exhibited that the topology of the TCP domain is different from the typical bHLH structure by comparing the ß-strand conformation of the basic region in a typical TCP domain with that of a typical bHLH protein (MyoD, PDB:1mdy), and concluded that the bHLH domain of TCP conforms to a new topology distinct from a typical bHLH structure.…”

Section: Tcp Conserved Domainsmentioning

confidence: 99%

Genomic survey of TCP transcription factors in plants: Phylogenomics, evolution and their biology

Zhou

Hwarari

et al. 2022

Front. Genet.

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The TEOSINTE BRANCHED1 (TBI1), CYCLOIDEA (CYC), and PROLIFERATING CELL NUCLEAR ANTIGEN FACTORS (PCF1 and PCF2) proteins truncated as TCP transcription factors carry conserved basic-helix-loop-helix (bHLH) structure, related to DNA binding functions. Evolutionary history of the TCP genes has shown their presence in early land plants. In this paper, we performed a comparative discussion on the current knowledge of the TCP Transcription Factors in lower and higher plants: their evolutionary history based on the phylogenetics of 849 TCP proteins from 37 plant species, duplication events, and biochemical roles in some of the plants species. Phylogenetics investigations confirmed the classification of TCP TFs into Class I (the PCF1/2), and Class II (the C- clade) factors; the Class II factors were further divided into the CIN- and CYC/TB1- subclade. A trace in the evolution of the TCP Factors revealed an absence of the CYC/TB1subclade in lower plants, and an independent evolution of the CYC/TB1subclade in both eudicot and monocot species. 54% of the total duplication events analyzed were biased towards the dispersed duplication, and we concluded that dispersed duplication events contributed to the expansion of the TCP gene family. Analysis in the TCP factors functional roles confirmed their involvement in various biochemical processes which mainly included promoting cell proliferation in leaves in Class I TCPs, and cell division during plant development in Class II TCP Factors. Apart from growth and development, the TCP Factors were also shown to regulate hormonal and stress response pathways. Although this paper does not exhaust the present knowledge of the TCP Transcription Factors, it provides a base for further exploration of the gene family.

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TCP Genes and the Orchestration of Plant Architecture

Cited by 8 publications

References 84 publications

TCP15 interacts with GOLDEN2‐LIKE 1 to control cotyledon opening in Arabidopsis

TCP15 interacts with GOLDEN2‐LIKE 1 to control cotyledon opening in Arabidopsis

Physiological Roles and Mechanisms of Action of Class I TCP Transcription Factors

Genomic survey of TCP transcription factors in plants: Phylogenomics, evolution and their biology

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