Physiological Roles and Mechanisms of Action of Class I TCP Transcription Factors

Viola, Ivana L.; Alem, Antonela L; Jure, Rocío M.; González, Daniel H.

doi:10.3390/ijms24065437

Cited by 19 publications

(15 citation statements)

References 143 publications

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“…In various plant species, members of the TCP gene family act as transcription factors that regulate plant growth and development ( Ma et al., 2016 ; Lan and Qin, 2020 ; Zhang et al., 2020 ; Viola et al., 2023 ). Since transcription factors regulate the transcription of target genes within the nucleus, DnTCPs are likely to be localized in the nucleus.…”

Section: Resultsmentioning

confidence: 99%

“…Meanwhile, CYC/TB1 members play crucial roles in lateral branching ( Doebley et al., 1997 ; Aguilar-Martínez et al., 2007 ) and flower symmetry ( Preston et al., 2011 ; Zhao et al., 2018 ; Pan et al., 2022 ). Unlike the functions of Class II members, most Class I TCP members remain unclear and have mainly been characterized in model plants ( Viola et al., 2023 ). Class I TCP genes influence the development of leaves ( Aguilar-Martínez and Sinha, 2013 ), cotyledons ( Alem et al., 2022 ), stamens, gynoecium ( Lucero et al., 2015 ), and seeds ( Resentini et al., 2015 ) mainly through promoting or repressing cell proliferation and cell cycle-related processes.…”

Section: Introductionmentioning

confidence: 99%

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Genome-wide identification and characterization of TCP gene family in Dendrobium nobile and their role in perianth development

Wei,

Yuan,

Zheng

et al. 2024

Front. Plant Sci.

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TCP is a widely distributed, essential plant transcription factor that regulates plant growth and development. An in-depth study of TCP genes in Dendrobium nobile, a crucial parent in genetic breeding and an excellent model material to explore perianth development in Dendrobium, has not been conducted. We identified 23 DnTCP genes unevenly distributed across 19 chromosomes and classified them as Class I PCF (12 members), Class II: CIN (10 members), and CYC/TB1 (1 member) based on the conserved domain and phylogenetic analysis. Most DnTCPs in the same subclade had similar gene and motif structures. Segmental duplication was the predominant duplication event for TCP genes, and no tandem duplication was observed. Seven genes in the CIN subclade had potential miR319 and -159 target sites. Cis-acting element analysis showed that most DnTCP genes contained many developmental stress-, light-, and phytohormone-responsive elements in their promoter regions. Distinct expression patterns were observed among the 23 DnTCP genes, suggesting that these genes have diverse regulatory roles at different stages of perianth development or in different organs. For instance, DnTCP4 and DnTCP18 play a role in early perianth development, and DnTCP5 and DnTCP10 are significantly expressed during late perianth development. DnTCP17, 20, 21, and 22 are the most likely to be involved in perianth and leaf development. DnTCP11 was significantly expressed in the gynandrium. Specially, MADS-specific binding sites were present in most DnTCP genes putative promoters, and two Class I DnTCPs were in the nucleus and interacted with each other or with the MADS-box. The interactions between TCP and the MADS-box have been described for the first time in orchids, which broadens our understanding of the regulatory network of TCP involved in perianth development in orchids.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Genome-wide identification and characterization of TCP gene family in Dendrobium nobile and their role in perianth development

Wei,

Yuan,

Zheng

et al. 2024

Front. Plant Sci.

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“…The TCP protein, as a group of plant-specific transcription factors, evolved from algae and bryophytes and is named after the earliest identified members of the family: TB1 (TEOSINTE BRANCHED 1) in maize, CYCLOIDEA (CYC) in Cynoglossum, and Proliferating Cell Factor 1/2 (PCF1/2) in rice ( Cubas et al., 1999 ). All members of the TCP protein contain a highly conserved basic helix-loop-helix (bHLH) structure consisting of 59 amino acid residues and can be divided into two subclasses based on the structural differences of TCP, including Class I (TCP-P/PCF) and Class II (TCP-C/CIN, TCP-C/CYC and TB1) ( Viola et al., 2023 ). The TCP gene family is widespread in the plant kingdom, and its family members can directly or indirectly bind to regulatory target genes, which regulate multiple processes of plant growth and development ( Zhou et al., 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Genome-wide characterization of TCP family and their potential roles in abiotic stress resistance of oat (Avena sativa L.)

Pan,

Ju,

et al. 2024

Front. Plant Sci.

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The TCP gene family members play multiple functions in plant growth and development and were named after the first three family members found in this family, TB1 (TEOSINTE BRANCHED 1), CYCLOIDEA (CYC), and Proliferating Cell Factor 1/2 (PCF1/2). Nitrogen (N) is a crucial element for forage yield; however, over-application of N fertilizer can increase agricultural production costs and environmental stress. Therefore, the discovery of low N tolerance genes is essential for the genetic improvement of superior oat germplasm and ecological protection. Oat (Avena sativa L.), is one of the world’s staple grass forages, but no genome-wide analysis of TCP genes and their roles in low-nitrogen stress has been performed. This study identified the oat TCP gene family members using bioinformatics techniques. It analyzed their phylogeny, gene structure analysis, and expression patterns. The results showed that the AsTCP gene family includes 49 members, and most of the AsTCP-encoded proteins are neutral or acidic proteins; the phylogenetic tree classified the AsTCP gene family members into three subfamilies, and each subfamily has different conserved structural domains and functions. In addition, multiple cis-acting elements were detected in the promoter of the AsTCP genes, which were associated with abiotic stress, light response, and hormone response. The 49 AsTCP genes identified from oat were unevenly distributed on 18 oat chromosomes. The results of real-time quantitative polymerase chain reaction (qRT-PCR) showed that the AsTCP genes had different expression levels in various tissues under low nitrogen stress, which indicated that these genes (such as AsTCP01, AsTCP03, AsTCP22, and AsTCP38) played multiple roles in the growth and development of oat. In conclusion, this study analyzed the AsTCP gene family and their potential functions in low nitrogen stress at the genome-wide level, which lays a foundation for further analysis of the functions of AsTCP genes in oat and provides a theoretical basis for the exploration of excellent stress tolerance genes in oat. This study provides an essential basis for future in-depth studies of the TCP gene family in other oat genera and reveals new research ideas to improve gene utilization.

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“…TCP proteins participate in the regulation of numerous processes of growth and development during the life cycle of plants, such as germination, photomorphogenesis, thermomorphogenesis, leaf development, flowering, development of floral organs, outgrowth of shoot branches, pollen development, circadian rhythms, cell cycle regulation, defense against pathogens, and senescence, acting through the recruitment of other factors and the modulation of different hormonal pathways [16][17][18][19][20]. Since their discovery more than 20 years ago, a considerable advance has been made in the knowledge of the roles of TCP transcription factors in plant reproductive development in diverse species.…”

Section: Introductionmentioning

confidence: 99%

TCP Transcription Factors in Plant Reproductive Development: Juggling Multiple Roles

Viola

González

2023

Biomolecules

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TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) transcription factors (TFs) are plant-specific transcriptional regulators exerting multiple functions in plant growth and development. Ever since one of the founding members of the family was described, encoded by the CYCLOIDEA (CYC) gene from Antirrhinum majus and involved in the regulation of floral symmetry, the role of these TFs in reproductive development was established. Subsequent studies indicated that members of the CYC clade of TCP TFs were important for the evolutionary diversification of flower form in a multitude of species. In addition, more detailed studies of the function of TCPs from other clades revealed roles in different processes related to plant reproductive development, such as the regulation of flowering time, the growth of the inflorescence stem, and the correct growth and development of flower organs. In this review, we summarize the different roles of members of the TCP family during plant reproductive development as well as the molecular networks involved in their action.

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Physiological Roles and Mechanisms of Action of Class I TCP Transcription Factors

Cited by 19 publications

References 143 publications

Genome-wide identification and characterization of TCP gene family in Dendrobium nobile and their role in perianth development

Genome-wide identification and characterization of TCP gene family in Dendrobium nobile and their role in perianth development

Genome-wide characterization of TCP family and their potential roles in abiotic stress resistance of oat (Avena sativa L.)

TCP Transcription Factors in Plant Reproductive Development: Juggling Multiple Roles

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