Tc-99m sestamibi uptake in the chest mimicking a malignant lesion of the breast

Civelek, A. Cahid; Patel, Pavni; Ozalp, Elcin; Brem, Rachel F.

doi:10.1016/j.breast.2004.11.003

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…99m Tc‐sestamibi is a second‐line diagnostic test after mammography approved to assist in the evaluation of breast lesions in patients with an abnormal mammogram of breast mass (Sampalis et al., 2003; Khalkhali et al., 2002). False positives can be caused by uptake of the radiotracer in the chest as a result of physiological activity in the auricular aspect of the right atrium (Civelek et al., 2006). A recent study (Brem et al., 2007) has shown a breast specific gamma camera imaging system has comparable sensitivity and greater specificity than MRI (Sweeney and Sacchini, 2007) for the detection of breast cancer in patients with equivocal mammograms.…”

Section: Nuclear Medicinementioning

confidence: 99%

Imaging and cancer: A review

2008

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Multiple biomedical imaging techniques are used in all phases of cancer management. Imaging forms an essential part of cancer clinical protocols and is able to furnish morphological, structural, metabolic and functional information. Integration with other diagnostic tools such as in vitro tissue and fluids analysis assists in clinical decision-making. Hybrid imaging techniques are able to supply complementary information for improved staging and therapy planning. Image guided and targeted minimally invasive therapy has the promise to improve outcome and reduce collateral effects. Early detection of cancer through screening based on imaging is probably the major contributor to a reduction in mortality for certain cancers. Targeted imaging of receptors, gene therapy expression and cancer stem cells are research activities that will translate into clinical use in the next decade. Technological developments will increase imaging speed to match that of physiological processes. Targeted imaging and therapeutic agents will be developed in tandem through close collaboration between academia and biotechnology, information technology and pharmaceutical industries.

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Section: Nuclear Medicinementioning

confidence: 99%

Imaging and cancer: A review

2008

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“…Scintimammography by sestamibi has been used as a method for the detection of breast cancer [2]. Nevertheless, false-positive results had been reported due to fibroadenoma, fibrocystic disease, focal atypical hyperplasia, granuloma, papilloma, breast involution, sclerosing adenosis, hematoma, focal inflammatory reaction (scarring, mastitis, and foreign mass reaction), benign angiomyoepithelioma, gynecomastia, pitfalls of interpretation, and even in the normal breast tissue [3][4][5][6][7].…”

Section: Discussionmentioning

confidence: 99%