Tc-99m Human Serum Albumin (Hsa) Scintigraphy in Children With Protein Loosing Enteropathy

Halaby, Hanaa; Bakheet, Siema M.; Al-Mehaidib, Ali; Shabib, Souheil M.; Nazer, Deina H.; Powe, John; Nazer, Hisham M.

doi:10.1097/00005176-199810000-00121

Cited by 11 publications

(13 citation statements)

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“…Authors of another study (16) detected PLE in 12 of 18 children but gave no data about the six negative scan results, nor did they state whether 24-hour imaging was being performed. We think the distinct results can be attributed to two possible causes: (a) different amounts of protein loss from the gastrointestinal tract, and (b) the performance of 24-hour imaging to document the sites of protein loss in our study.…”

Section: Discussionmentioning

confidence: 99%

Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy

Chiu

Lee²,

Hwang

et al. 2001

Radiology

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Section: Discussionmentioning

confidence: 99%

Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy

Chiu

Lee²,

Hwang

et al. 2001

Radiology

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“…The diagnosis is confirmed by increased faecal concentration of a-1-antitrypsin, dilated lymphatic veins in upper gastrointestinal tract endoscopic examination, and loss of bowel wall segments at Tc-99m scintigraphy. 1,2 Treatment of protein-losing enteropathy includes the nutrition state maintenance by using a highprotein diet with supplement of fat-soluble vitamins and low fat with medium chain triglycerides, spironolactone, diuretics, angiotensin-converting enzyme inhibitors, octreotide, and unfractionated heparin, which have membrane-stabilising and antiinflammatory effects. With the progress in the pulmonary vasoactive drugs such as phosphodiesterase inhibitors -sildenafil -and endothelin antagonistsbosentan -regulation of pulmonary vascular resistance and systemic venous pressure has been settled in the treatment of protein-losing enteropathy.…”

Section: Discussionmentioning

confidence: 99%

Use of oral budesonide in the management of protein-losing enteropathy due to restrictive cardiomyopathy

2013

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A 7-year-old male patient who had abdominal swelling and eyelid oedema was diagnosed with restrictive cardiomyopathy. His serum albumin level was 2.3 g/dl. Protein-losing enteropathy due to restrictive cardiomyopathy was diagnosed and oral budesonide was started. His serum albumin level began to rise and ascites and peripheric oedema disappeared. The patient underwent a successful cardiac transplantation and budesonide was stopped. After the heart transplantation, the albumin level decreased to 2.3 g/dl, and therefore it was restarted. When the serum albumin level increased, the budesonide dose was tapered and stopped in 1 month. Budesonide may be an effective drug in patients with protein-losing enteropathy due to heart failure.

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“…[16][17][18] Recently, one CCS patient had protein-losing enteropathy that was successfully corrected by surgical management after localization of the level of protein-losing area over the ascending colon. 8 In our report, we also had a CCS patient with protein-losing enteropathy that was successfully localized over the transverse and descending colons by 99m Tc HSA scan.…”

Section: Discussionmentioning

confidence: 99%

Application of Technetium-99m-Labeled Human Serum Albumin Scan to Assist Surgical Treatment of Protein-Losing Enteropathy in Cronkhite-Canada Syndrome: Report of A Case

Tseng

Sheu

Lee

et al. 2005

Diseases of the Colon &Amp; Rectum

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Cronkhite-Canada syndrome is a rare form of nonhereditary gastrointestinal polyposis associated with ectodermal change and protein-losing enteropathy. Here we report a 63-year-old male presenting with diffuse gastrointestinal polyposis, onychodystrophy, cutaneous pigmentation, alopecia, diarrhea, hypoalbuminemia and lower leg edema. Technetium-99m-labeled human serum albumin scan confirmed the patient to have protein-losing enteropathy, which originated from the transverse and descending colon. Subtotal colectomy was performed. Albumin level and ectodermal change were gradually improved during three years of outpatient clinic follow-up. Based on our finding, Technetium-99m-labeled human serum albumin scintigraphy is helpful to localize the protein-losing origins and surgery is an effective treatment for Cronkhite-Canada syndrome with protein-losing enteropathy.

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Tc-99m Human Serum Albumin (Hsa) Scintigraphy in Children With Protein Loosing Enteropathy

Cited by 11 publications

References 0 publications

Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy

Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy

Use of oral budesonide in the management of protein-losing enteropathy due to restrictive cardiomyopathy

Application of Technetium-99m-Labeled Human Serum Albumin Scan to Assist Surgical Treatment of Protein-Losing Enteropathy in Cronkhite-Canada Syndrome: Report of A Case

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Tc-99m Human Serum Albumin (Hsa) Scintigraphy in Children With Protein Loosing Enteropathy

Cited by 11 publications

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Protein-losing Enteropathy: Diagnosis with99mTc-labeled Human Serum Albumin Scintigraphy

Protein-losing Enteropathy: Diagnosis with99mTc-labeled Human Serum Albumin Scintigraphy

Use of oral budesonide in the management of protein-losing enteropathy due to restrictive cardiomyopathy

Application of Technetium-99m-Labeled Human Serum Albumin Scan to Assist Surgical Treatment of Protein-Losing Enteropathy in Cronkhite-Canada Syndrome: Report of A Case

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Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy

Protein-losing Enteropathy: Diagnosis with^99mTc-labeled Human Serum Albumin Scintigraphy