Tassement vertébral révélant une leucémie aiguë chez un enfant

Hbibi, Mohamed; Atmani, S.; Abourazzak, S.; Kamaoui, Imane; Chaouki, S.; Bouharrou, A.; Hida, M.

doi:10.1016/j.arcped.2011.01.012

Cited by 2 publications

(3 citation statements)

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“…The osteoarticular manifestations are frequent in the ALL. Osteopenia, lysis of bone, lesions of osteosclerosis and periosteal reactions have been described [4][5][6]. Vertebral compression is rarely a first manifestation of ALL.…”

Section: Discussionmentioning

confidence: 99%

“…There are a mean of 7 weeks between the discovery of the vertebral collapse and hematologic diagnosis [4]. This delay is due, firstly, to the fact that many diagnostic can discuss: isthmic spondylolysis, Schumann's disease, spondylodiscitis and bone malignancies [5,6], David et al reported a retrospective study of 29 cases of children with malignancies initially addressed in pediatric rheumatology unit (juvenile chronic arthritis, spondyloarthropathies ...) [3], on the other hand, the possible absence of biological orientation with an initial normal blood count [6].…”

Section: Discussionmentioning

confidence: 99%

“…The treatment of vertebral collapse is double: orthopedic by wearing a corset for some authors [7] and the specific treatment of ALL [5,6]. Our patient received an orthopedic treatment with chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

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Vertebral Body Collapse at the Onset of Acute Lymphoblastic Leukemia

Cherkaoui¹,

Hmimech²,

Madani³

et al. 2014

PRIJ

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Bone and joint pain may be a presenting symptom in 25% of patients with acute leukemia; whereas generalised osteopenia and vertebral complications are less common. An 11 years old boy reported a persistent low back pain since 6 weeks. The physical exam showed exquisite vertebral pain. Imaging objectified vertebral body collapse L1 and L2. Count blood cells found pancytopenia without blasts. B acute lymphoblastic leukemia was diagnosed. The boy received chemotherapy with orthopedic treatment. He was followed for two and half a year on complete remission. Although the diagnosis of ALL was delayed because this unusual presenting complication was not recognized as such, the outcome was good.

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Section: Discussionmentioning

confidence: 99%