Targetoid pattern of hair regrowth in alopecia areata: a case report

El-Dars, L D; Kamath, S.; Logan, Richard A.

doi:10.1111/j.1365-2230.2008.02943.x

Cited by 6 publications

(5 citation statements)

References 3 publications

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“…And lastly atypical black hair regrowth in red-haired AA patients was described (Sinclair red hair) [12]. Targetoid hair regrowth pattern (THRP) in AA was first described by Orecchia and Rabbiosi in 1988 [13]. El-Dars et al also described a THRP in a patient with AA treated with topical corticosteroid gel [14].…”

Section: Discussionmentioning

confidence: 99%

Targetoid Polycyclic Concentric Hair Regrowth Pattern Is a Sign of Immunological Recovery in Alopecia Areata

Sharquie¹,

Ahmed²,

Sharquie³

2018

JCDSA

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Background: Alopecia areata is a common autoimmune disease, where there are many topical and systemic therapies, during which hair growth appears in a uniform pattern. In certain cases, hair regrowth takes a polycyclic pattern simulating a target, so called targetoid phenomena. Objective: To screen all cases of treated alopecia areata for hair targetoid regrowth pattern. Methods: This is an observational study, was conducted in Dermatology Department of Baghdad Teaching Hospital in Iraq, during the period, August 2017 to October 2017. All cases treated for alopecia areata with IM triamcinolone 20-40 mg injection every 2 weeks with topical clobetasone ointment and zinc sulfate 2 mg/kg/day for 2 months, were examined for the targetoid concentric hair regrowth pattern. Result: Among all cases of alopecia areata, seven patients were recorded to have the targetoid concentric hair pattern, which seen 2-4 weeks after therapy, their ages ranged from 4 to 25 years old with a mean 14.5, all of them were males. All these patients returned back with hair growth in a form of rings of hair growth alternating with rings of little or no hair growth forming a typical picture of target. Conclusion: Targetoid polycyclic concentric hair regrowth pattern is an important phenomenon seen in patients receiving treatment for alopecia areata, which is a good sign of recovery where its etiopathogenesis could not well be elucidated but alternating immunological reactions could explain this targetoid pattern.

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Section: Discussionmentioning

confidence: 99%

Targetoid Polycyclic Concentric Hair Regrowth Pattern Is a Sign of Immunological Recovery in Alopecia Areata

Sharquie¹,

Ahmed²,

Sharquie³

2018

JCDSA

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“…also described a THRP in a patient with AA treated with topical corticosteroid gel. [ 8 ] Del Río described a patient treated with intradermal triamcinolone for AA and developed a THRP. [ 9 ] The THRP was also described by Tan and Delaney in eight patients as a possible result of the centrifugal accumulation of the corticosteroid cream.…”

Section: Discussionmentioning

confidence: 99%

“…The theories of the anagen/telogen wave and the possible corticosteroid accumulation effect are not fully understood. [ 7 8 9 ]…”

Section: Discussionmentioning

confidence: 99%

Concentric polycyclic regrowth pattern in alopecia areata

et al. 2016

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Alopecia areata (AA) is a common form of autoimmune nonscarring hair loss of scalp and/or body. Atypical hair regrowth in AA is considered a rare phenomenon. It includes atypical pattern of hair growth (sudden graying, perinevoid alopecia, Renbok phenomenon, castling phenomenon, and concentric or targetoid regrowth) and atypical dark color hair regrowth. We report a case of AA that resulted in a concentric targetoid hair regrowth and discuss the possible related theories regarding the significance of this phenomenon.

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“…In 1988, Orecchia and Rabbiosi reported the first case of concentric regrowth, where he explained with the centrifugal wave theory that AA begins as an epicenter before progressing peripherally in a centrifugal wavelike manner [5]. There have been some cases reported since then, but none provided with a satisfactory explanation [6,7]. Animal experiments have shown that telogen can be divided into a refractory phase followed by a competent phase [8].…”

Section: Casementioning

confidence: 99%