Tardive movement disorders: a practical approach

Saifee, Tabish A.; Edwards, Mark J.

doi:10.1136/practneurol-2011-000077

Cited by 10 publications

(4 citation statements)

References 30 publications

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“…10 The significant improvement in the symptoms of PS after the withdrawal of antipsychotic and dopaminergic drugs differentiates this syndrome from tardive dystonia, 41 which is triggered exclusively with dopamine receptor blockers such as antipsychotics, typically after chronic treatment (an average of 5 years) and is often persistent or even permanent even when the offending drug is discontinued. 49 The most important differential diagnosis is scoliosis, which is defined as the lateral curvature of the spine with a Cobb angle of 10 degrees or more in the coronal plane as measured on a radiograph. 50 Scoliosis features a rotational component because of the 3-dimensional structural deformity with a curvature in the anterior-posterior plane, angulation in the sagittal plane, and rotation in the transverse plane.…”

Section: Differential Diagnosismentioning

confidence: 99%

Pisa Syndrome

Michel¹,

Oscar²,

Correa³

et al. 2015

Clinical Neuropharmacology

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Lateral trunk flexion is often seen in patients with Parkinson disease, sometimes coming on as a subacute phenomenon associated with medication adjustments, and in others with gradual onset that seems related to a neurodegenerative process related to the evolution of the disease.Either acute or subacute presentations seem to be pure abnormalities in the coronal plane and are usually reversible. However, a chronic form occurs often in a combined fashion with anteroposterior flexion (camptocormia), improves only partially, remains stable, or even worsens over time.The acute/subacute phenotype is the condition originally named as Pisa syndrome (PS).The pathophysiology of PS remains poorly understood, and a cholinergic-dopaminergic imbalance has been suggested as being involved in the cause of this disorder. The role of other neurotransmitters and how they become dysfunctional in PS remains to be elucidated.Specific treatments, other than discontinuing the medications responsible for the disorder, whenever possible, are undeveloped because of the unknown etiology.

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Section: Differential Diagnosismentioning

confidence: 99%

Pisa Syndrome

Michel¹,

Oscar²,

Correa³

et al. 2015

Clinical Neuropharmacology

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“…PS can be differentiated from tardive dystonia [44], which is triggered by intake of dopamine receptor blockers such as antipsychotics for other causes, typically after chronic treatment of around 5 years, which may be persistent or even permanent even when the offending drug is discontinued [52]. Scoliosis is de ined as the lateral curvature of the spine PS [62].…”

Section: Diff Erential Diagnosismentioning

confidence: 99%

PISA Syndrome-Orthopedic manifestation of a neurological disease?

Dutta¹

2020

J Neurosci Neurol Disord

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“…Bei diesen Patienten wird eine Umstellung der antipsychotischen Therapie auf eine Substanz mit geringerem Risiko für TD oder die symptomatische medikamentöse Therapie der TD empfohlen. In Reviews wird häufig die Umstellung auf Clozapin oder Quetiapin empfohlen [37,49].…”

Section: Behandlung Der Tardiven Dyskinesieunclassified