Antipsychotikainduzierte tardive Syndrome

Fleischhacker, W. Wolfgang; Hofer, Alex; Jagsch, Christian; Pirker, Walter; Psota, Georg; Rittmannsberger, Hans; Seppi, Klaus

doi:10.1007/s40211-016-0189-7

Cited by 8 publications

(6 citation statements)

References 51 publications

(40 reference statements)

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“…Tardive Dyskinesia (TD) is a common movement disorder caused by the intake of antipsychotics [10]. Characteristic for TD are irregular movements that usually affect motions of the tongue, lips, jaw, and face, and sometimes the peri-orbital area [11].…”

Section: Tardive Dyskinesiamentioning

confidence: 99%

Ginkgo biloba Extracts Like EGb 761® for Treatment of Non Common Indications – A Selection of Clinical Studies

Pfuhlmann,

Koch,

Langhorst

2023

Zeitschrift für Phytotherapie

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Extracts of Ginkgo biloba L. are one of the most commonly applied herbal medicines. The active constituents are flavonol glycosides and terpene trilactones in particular. The special extract EGb 761® is mentioned in the German S3 clinical guideline “Demenzen” as treatment option (“kann” recommendation). Some small- and large-scale clinical studies for Ginkgo biloba leaf extracts are summarized in this publication for the indications: Tardive dyskinesia, vitiligo, anxiety/anxiety disorder, visual impairment, mountain sickness, sudden hearing loss, attention deficient hyperactivity disorder (ADHD) in children and fatigue. The studies are of different quality and show variable results. More research is warranted to draw conclusions about the effectiveness of Ginkgo biloba extracts for those indications.

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Section: Tardive Dyskinesiamentioning

confidence: 99%

Ginkgo biloba Extracts Like EGb 761® for Treatment of Non Common Indications – A Selection of Clinical Studies

Pfuhlmann,

Koch,

Langhorst

2023

Zeitschrift für Phytotherapie

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“…Sie kann aber auch mit myokloniformen Extremitätenbewegungen, Ganganomalien, Schluck-und Sprechstörungen einhergehen. In vielen Fällen sind sich die Patienten dieser Bewegungen nicht bewusst [10].…”

Section: Hintergrund Definition Und Differentialdiagnosenunclassified

“…Demnach führt die regelmäßige Einnahme von DRA zu einer Sensibilisierung der Dopaminrezeptoren, was in einem Überschießen der dopaminergen Neurotransmission im nigrostriatalen System und damit im Verlust der Bewegungskontrolle resultiert. Während die direkte Evidenz für diese Hypothese im Tiermodell sehr stark ist, konnte Gültigkeit beim Menschen nicht bestätigt werden[10]. Die verschiedenen pathophysiologischen Hypothesen fasst ▶Tab.…”

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“…Zum anderen wird der Gruppe der SGA z. B. Risperidon zugerechnet, dessen Rezeptorprofil sich wenig von Haloperidol unterscheidet, was den Unterschied wieder verkleinert[10].Bei der Angabe der Prävalenzen wird aktuell häufig die Metaanalyse mit fast 12000 Patienten von Carbon und Mitarbeitern ▶Tab. 2 wichtige Differentialdiagnosen zur TD (Daten nach[22,23]) Fortschr Neurol Psychiatr 2019; 87: 217-224 aus dem Jahr 2017 zitiert.…”

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Prävention und Behandlung von Antipsychotika-induzierten tardiven Dyskinesien

Erbe¹

2018

Fortschr Neurol Psychiatr

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Tardive dyskinesias (TDs) are still common long-term sequelae of antipsychotic treatment. They are generally irreversible and associated with cognitive deficits, a decrease in quality of life and increased mortality. Furthermore, they potentially contribute to further stigmatization of the affected patients. However due to limited treatment options, antipsychotic drugs are still one of the cornerstones in treatment of most severe mental illnesses. Therefore, knowledge about risk factors and prevention of TDs is crucial. If TDs occur, the immediate optimization of the antipsychotic drug regimen is required. Targeted medical treatments such as VMAT - 2 inhibitors can be considered. The novel VMAT-2 inhibitors are not yet approved in Germany. Other drugs that are currently used to treat TDs include clonazepam and gingko biloba. This review summarizes the current evidence of treatment options of TDs and seeks to formulate clinical recommendations for the prevention and management of TDs.

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“…Bunlar, geç diskinezinin klasik formu dışında distoni, akatizi, parkinsonizm, tremor, miyoklonus, tik bozukluğu gibi fenomenolojik ve deskriptif olarak farklı tablolardır. 4,5 …”

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Antipsychotic-Induced Tardive Syndromes: Clinical Features and Treatment Approaches

Uzun¹,

Aylak²

2017

Turkiye Klinikleri J Med Sci

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Antipsychotikainduzierte tardive Syndrome

Cited by 8 publications

References 51 publications

Ginkgo biloba Extracts Like EGb 761® for Treatment of Non Common Indications – A Selection of Clinical Studies

Ginkgo biloba Extracts Like EGb 761® for Treatment of Non Common Indications – A Selection of Clinical Studies

Prävention und Behandlung von Antipsychotika-induzierten tardiven Dyskinesien

Antipsychotic-Induced Tardive Syndromes: Clinical Features and Treatment Approaches

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