Tannin-fluoride preparation attenuates prostaglandin E2 production by dental pulp cells

Nakamura, Kōichi; Deyama, Yoshiaki; Yoshimura, Yoshitaka; Hashimoto, Masanori; Kaga, Masayuki; Suzuki, Kuniaki; Yawaka, Yasutaka

doi:10.3892/mmr.2011.476

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…Dental bonding agents induce COX-2 overexpression in gingival fibroblasts 103 . Tannin fluoride suppresses COX-2 and PGE2 expression induced by glass ionomer cement in dental pulp cells 104 .…”

Section: Dental Materials and Other Substances That Modulate Cox Expr...mentioning

confidence: 99%

The importance of cyclooxigenase in dentistry

Barrera,

Cepeda,

Parras

2024

Braz.j. of oral sci.

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Aim: Cyclooxygenase enzymes (COX) catalyze the conversion of arachidonic acid to prostaglandins and thromboxanes during pain and inflammation conditions. These enzymes have also been linked to several other conditions and diseases, and hence, in dentistry, it is crucial to identify the processes that increase the levels of these mediators. This paper aims to describe the significance of COX in dental practice through a narrative review. Methods: Articles relating to COX upregulation published in English and Spanish over the last 51 years in databases such as EBSCO, Google Scholar, Science Direct, PubMed, and Web of Science; were analyzed. Results: A total of 115 articles demonstrating the relationship between COX upregulation and multiple conditions and diseases of importance in prosthodontics, periodontics, oral pathology, orthodontics, and endodontics were included. Conclusions: COX upregulation is related to inflammatory and malignant diseases in oral tissues, such as periodontitis, pulpitis, and oral cancer, nevertheless, its expression is advantageous in other fields of study such as orthodontics. Additionally, is well documented that dental materials provoke an undesired increase in COX expression, which could be a significant factor that directly affects pulpal health.

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Section: Dental Materials and Other Substances That Modulate Cox Expr...mentioning

confidence: 99%

The importance of cyclooxigenase in dentistry

Barrera,

Cepeda,

Parras

2024

Braz.j. of oral sci.

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Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction

et al. 2021

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Late-life mild cognitive impairment and dementia represent a significant burden on healthcare systems and a unique challenge to medicine due to the currently limited treatment options. Plant phytochemicals have been considered in alternative, or complementary, prevention and treatment strategies. Herbals are consumed as such, or as food supplements, whose consumption has recently increased. However, these products are not exempt from adverse effects and pharmacological interactions, presenting a special risk in aged, polymedicated individuals. Understanding pharmacokinetic and pharmacodynamic interactions is warranted to avoid undesirable adverse drug reactions, which may result in unwanted side-effects or therapeutic failure. The present study reviews the potential interactions between selected bioactive compounds (170) used by seniors for cognitive enhancement and representative drugs of 10 pharmacotherapeutic classes commonly prescribed to the middle-aged adults, often multimorbid and polymedicated, to anticipate and prevent risks arising from their co-administration. A literature review was conducted to identify mutual targets affected (inhibition/induction/substrate), the frequency of which was taken as a measure of potential interaction. Although a limited number of drugs were studied, from this work, interaction with other drugs affecting the same targets may be anticipated and prevented, constituting a valuable tool for healthcare professionals in clinical practice.

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Evaluation of effect of poultice (Upanaha Sweda) in low back pain (Katigraha): A randomized comparative clinical trial

Kumar

Sanapeti

Prasad

2019

AYU

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Background: Katigraha (low back pain) is a condition where low back is afflicted either with Vata or Sama Vata ( Vata involved with the toxins released due to altered digestion and metabolism) and present with symptoms such as pain with stiffness. About 60%–80% population in India suffer from this condition. Upanaha Sweda (poultice) is one of the Swedana (sudation) treatment modalities mentioned for Katigraha . As Sama (affected with toxins released from impaired digestion) and Nirama (without toxins) are two stages of Katigraha , hence, the specific type of Upanaha is required for such condition. Aims and Objective: The study was conducted to evaluate the effect of Upanaha Sweda in Katigraha (low back pain) as per the presentation of stages of Ama . Materials and Methods: Selected patients were categorized into two groups. In group A, patients having Samaja Katigraha , were given Panchakoladi Upanaha once a day till it became Niramaja , then shifted to Godhumadi Upanaha for 7 days and patients who had Niramaja Katigraha, Godhumadi Upanaha was used once a day for 7 days. In group B Godhumadi Upanaha was used once a day for 7 days irrespective of stages. Subjective parameters assessed were pain in the low back, stiffness, and Oswestry Disability Index (ODI) was also used. The Mann–Whitney U test and Wilcoxon signed‑rank test were used to assess results. Results: Patients who were treated considering the Sama and Nirama phases had 78.88% better results in relieving pain, stiffness, and in ODI change than the patients treated without considering the phases . Conclusion: The present study showed significant results in both the groups, but patients treated as per stage wise treatment showed better effect in treating Katigraha than the patients treated with out considering the stage.

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Tannin-fluoride preparation attenuates prostaglandin E2 production by dental pulp cells

Cited by 3 publications

References 25 publications

The importance of cyclooxigenase in dentistry

The importance of cyclooxigenase in dentistry

Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction

Evaluation of effect of poultice (Upanaha Sweda) in low back pain (Katigraha): A randomized comparative clinical trial

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