Takotsubo cardiomyopathy due to cephalosporin anaphylaxis under general anaesthesia

Pathak, Soumi; Dubey, Mamta; Goel, Nitesh

doi:10.4103/0019-5049.177870

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Routine cardiac care, administering corticosteroids and antihistamines, and avoiding beta-blockers (due to exaggerated vasospasm related to overactive α-adrenergic receptors) are recommended (149)(150)(151)(152)(153). Takotsubo cardiomyopathy is a disease manifesting with the clinical, electrocardiographic, and biochemical evidence of myocardial infarction, but the ventricular dysfunction is transient (23,(154)(155)(156). Patients with long QT syndrome (LQTS) who develop anaphylaxis can receive glucagon, steroids, and epinephrine (157).…”

Section: Management Of Refractory Anaphylaxis In the Icumentioning

confidence: 99%

Critical Care Management of the Patient With Anaphylaxis: A Concise Definitive Review

Krishnaswamy

2021

Critical Care Medicine

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OBJECTIVES: Anaphylaxis is a rapidly progressive life-threatening syndrome manifesting as pruritus, urticaria, angioedema, bronchospasm and shock. The goal of this synthetic review is to provide a practical, updated approach to the evaluation and management of this disorder and associated complications. DATA SOURCES: A MEDLINE search was conducted with the MeSH of anaphylaxis, anaphylactic reaction, anaphylactic shock, refractory anaphylaxis and subheadings of diagnosis, classification, epidemiology, complications and pharmacology. The level of evidence supporting an intervention was evaluated based on the availability of randomized studies, expert opinion, case studies, reviews, practice parameters and other databases (including Cochrane). STUDY SELECTION: Selected publications describing anaphylaxis, clinical trials, diagnosis, mechanisms, risk factors and management were retrieved (reviews, guidelines, clinical trials, case series) and their bibliographies were also reviewed to identify relevant publications. DATA EXTRACTION: Data from the relevant publications were reviewed, summarized and the information synthesized. DATA SYNTHESIS: This is a synthetic review and the data obtained from a literature review was utilized to describe current trends in the diagnosis and management of the patient with anaphylaxis with a special emphasis on newer evolving concepts of anaphylaxis endotypes and phenotypes, management of refractory anaphylaxis in the ICU setting and review of therapeutic options for the elderly patient, or the complicated patient with severe cardiorespiratory complications. Most of the recommendations come from practice parameters, case studies or expert opinions, with a dearth of randomized trials to support specific interventions. CONCLUSION: Anaphylaxis is a rapidly progressive life-threatening disorder. The critical care physician needs to be familiar with the diagnosis, differential diagnosis, evaluation, and management of anaphylaxis. Skilled intervention in ICUs may be required for the patient with complicated, severe, or refractory anaphylaxis.

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Section: Management Of Refractory Anaphylaxis In the Icumentioning

confidence: 99%

Critical Care Management of the Patient With Anaphylaxis: A Concise Definitive Review

Krishnaswamy

2021

Critical Care Medicine

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“…In this issue of the Indian Journal of Anaesthesia, a case of this entity is reported after thyroidectomy and also one describing its occurrence in a young patient who developed anaphylaxis to cephalosporin intraoperatively during limb salvage surgery for osteosarcoma of the tibia. [ 1 2 ]…”

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confidence: 99%