Tako-Tsubo Cardiomyopathy and Thyroid Dysfunction

Sarullo, Filippo M.; Monaco, Antonio Di; Magro, Serena; Nerla, Roberto; Salerno, Ylenia; Mandalà, Giorgio; Lanza, Gaetano Antonio

doi:10.5812/kowsar.1726913x.3386

Cited by 4 publications

(6 citation statements)

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“…Sarullo et al. [ 15 ] analysed TTC in patients with hyperthyroidism while Cacciotti et al. [ 16 ] found hypothyroidism in 29.3 % of their patients with stress cardiomyopathy.…”

Section: Discussionmentioning

confidence: 99%

Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Zalewska-Adamiec

Bachórzewska−Gajewska

Tomaszuk‐Kazberuk

et al. 2016

Neth Heart J

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BackgroundTakotsubo cardiomyopathy (TTC) is characterised by transient contractility disturbances of the apex of the left ventricle.MethodsWe enrolled 101 patients from the northern-eastern part of Poland in the years 2008–2012 who were hospitalised for TCC. The control group consisted of female patients diagnosed with anterior myocardial infarction with ST-segment elevation (anterior STEMI) (n = 101).Results89 % of the study group were women. Patients with TTC had diabetes (12.6 % vs 29.7 %; p = 0.002) and hyperlipidaemia (36.8 % vs 64.4 %; p = 0.0001) significantly less frequently, and better kidney function assessed by estimated glomerular filtration rate versus patients with anterior STEMI (74.52 % vs 64.30 %; p = 0.004). In the TTC group there were more patients with chronic obstructive pulmonary disease (11.6 % vs 1.0 %; p = 0.002) and thyroid disturbances, especially hyperthyroidism (23.4 % vs 11.0 %; p = 0.021). In patients with TTC sudden cardiac arrest, pulmonary oedema and cardiogenic shock were observed less frequently than in the control group (14.7 % vs 30.7 %; p = 0.0078). Hospitalisations in TTC patients were less frequently complicated by pneumonia (20.0 % vs 35.6 %; p = 0.0148) and urinary infection (4.2 % vs 21.8 %; p = 0.0003). Cardiac rupture occurred in 3 patients with TTC and in 1 with anterior STEMI. In-hospital mortality was significantly lower in the group with TTC. Also, mortality at 30 days, 3 months, 1 year and 2.5 years was significantly lower in patients with TTC than in patients with MI (p = 0.035; p = 0.0226; p = 0.0075; p = 0.009).ConclusionsPreviously considered to be a benign syndrome, TTC should be reconsidered as a clinical condition at risk for serious complications such as cardiac arrest, cardiogenic shock, pulmonary oedema and cardiac rupture leading to death and causing substantial early hazard. The prognosis in TTC is significantly better than in patients with anterior STEMI.

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“…Sarullo et al. [ 15 ] analysed TTC in patients with hyperthyroidism while Cacciotti et al. [ 16 ] found hypothyroidism in 29.3 % of their patients with stress cardiomyopathy.…”

Section: Discussionmentioning

confidence: 99%

Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Zalewska-Adamiec

Bachórzewska−Gajewska

Tomaszuk‐Kazberuk

et al. 2016

Neth Heart J

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show abstract

“…1 It occurs mostly in postmenopausal women, as in our patient, and it presents as an acute coronary event without there being coronary disease. 2 Its course is usually benign and recovery is complete in most individuals. 3…”

Section: Discussionmentioning

confidence: 99%

Takotsubo cardiomyopathy in chronic infection

2013

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“…In recent years it was observed that younger females with TTC relatively often suffer from thyroid diseases [5]. We would like to present two cases of female patients with TTC and Hashimoto's disease.…”

mentioning

confidence: 99%

“…In recent years a few cases showing correlation of thyroid dysfunction with TTC have been published; for example, cases of TTC with hyperthyroidism in the course of Graves-Basedow disease, Hashimoto's disease, and cases connected with the use of levothyroxine [5].…”

mentioning

confidence: 99%