Tailoring self-assembled monolayers at the electrochemical interface

Varatharajan, S.; Berchmans, Sheela; Yegnaraman, V.

doi:10.1007/s12039-009-0080-1

Cited by 8 publications

(3 citation statements)

References 39 publications

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“…In the last decade, mixed SAM were preferred then the single alkanethiols due to time saving factor in fabrication. Some researchers collaborated the single SAM like MUA/DTT, MUA/MCH), DTSP 3-dithiobis-(sulfosuccinimidyl-propionate) (amine terminal), DTBA (carboxyl terminal), 16mercaptohexadecanoic acid (MHDA) (carboxyl terminal), Mercaptoacetic acid (MACA) (carboxyl terminal) [33]- [35].…”

Section: Synthesis Of Sammentioning

confidence: 99%

The Formation and Organization of Self-Assembled Monolayer (SAM) for Escherichia coli Detection: A Review

Muslihati¹,

Basri

Sahdan

et al. 2020

Proceedings of the 2nd International Conference of Science and Technology for the Internet of Things, ICSTI 2019, September 3rd

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SAM is known as a tuneable platform through an ultra-thin, biocompatible, and controlled organic film formed by self-assembled from a strong chemisorption of thiols (R-S-H) or its derivatives (R-OH, R-COO, R-COOH, R-NH2, etc.) onto metal or semiconductor substrate. The monolayer is offering hydrophobic-hydrophilic control depending on their terminal group. These flexibilities were functionalized in order to immobilize the biomolecule like DNA/RNA, antibody/antigen, bacteriophages, and aptamers as a selective receptor to capture E. coli selectively as the most dangerous microorganism in environmental water into an array system called biosensor. A number of methods have been developed to characterize the performance of SAM functionalization in immobilizing biomolecule for E. coli rapid detection and real time in optical and electrochemical (amperometric, potentiometric, and impedimetric). Till date, nano-materials and nanotechnologies has significantly contributed as a key role as in basic platform forming the sensor sensitively. Nano materials offer attractive properties like shape dependent physical and unique size, easy synthesize, easy surface functionalization, and enhancement of an electron transfer. This review will discuss the biomolecule immobilization techniques with SAM and the sensing mechanism.

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Section: Synthesis Of Sammentioning

confidence: 99%

The Formation and Organization of Self-Assembled Monolayer (SAM) for Escherichia coli Detection: A Review

Muslihati¹,

Basri

Sahdan

et al. 2020

Proceedings of the 2nd International Conference of Science and Technology for the Internet of Things, ICSTI 2019, September 3rd

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“…The electrodes were then immersed into the cysteamine solution to form the thio group of cysteamine on the Au surfaces and the amino group was extended out of the surface (Figs. 1(g)) [5]. The modified electrodes were immersed into the solution with glutaraldehyde and enzyme again.…”

Section: Chip Fabricationmentioning

confidence: 99%

An integrated microfluidic system for rapid HbA1c and glucose measurement

Lee

2013

2013 Transducers &Amp; Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems

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Diet management is crucial for diabetes to avoid a variety of complications. Due to the large fluctuations in glucose levels that naturally occur over the course of a day, it has been concluded that the biomarker for long-term glycaemic control is whole-blood glycated hemoglobin since its level responds to the long-term progression of diabetes without the short-term fluctuations such as glucose. In this study, an integrated microfluidic chip was developed for measurement of glucose and HbA1c. The whole blood was first separated into plasma and red blood cells (RBC) and then respectively transported into corresponding reaction biosensors with enzyme immobilization. Eventually, both blood glucose and HbA1c levels for short-term and long-term monitoring were measured. The automatic detection system can provide quick monitoring information for the diabetes patients.

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“…1, 2012 biosensors. 66 Biosensor devices, based on the conversion of molecular recognition reactions into useful response signals, offer considerable promise for biological analysis.…”

Section: State-of-the-artmentioning

confidence: 99%

Biomedical applications of nanobiosensors: the state-of-the-art

Rai¹,

Gade²,

Gaikwad³

et al. 2012

J. Braz. Chem. Soc.

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O desenvolvimento de nanobiosensores é um dos avanços mais recentes no campo da nanotecnologia. A investigação sobre nanobiosensores ópticos com dimensões submicrométricas tem aberto novos horizontes para as medições intracelulares. Aproveitando as propriedades únicas dos nanomateriais, nanobiosensores mais rápidos e sensíveis podem ser desenvolvidos. Além de serem sensíveis e rápidos, os estudos de nanobiosensores têm voltado seus esforços para o desenvolvimento de sensores baseados em nanomateriais que são acessíveis, robustos e reprodutíveis. Os nanobiosensores estão equipados com sondas biorreceptoras imobilizadas, por exemplo, anticorpos, substrato de enzima. A excitação por laser é transmitida para o sistema fotométrico na forma de sinal óptico (fluorescência). Os nanobiosessores poderão revolucionar no futuro o diagnóstico de doenças. A presente revisão discute os conceitos básicos, a evolução e as aplicações biomédicas de nanobiosensores.Development of nanobiosensor is one of the most recent advancement in the field of Nanotechnology. Research on optical nanobiosensors with submicron-sized dimensions has opened new horizons for intracellular measurements. Taking advantage of the unique properties of the nanomaterials, faster and sensitive nanobiosensors can be developed. Apart from being sensitive and fast, the studies related to nanobiosensors have geared their efforts towards the development of nanomaterial-based sensors that are affordable, robust and reproducible. The nanobiosensors are equipped with immobilized bioreceptor probes, e.g., antibodies, enzyme substrate. Laser excitation is transmitted to photometric system in the form of optical signal (fluorescence). Nanobiosensors will revolutionize the future of disease diagnosis. The present review discusses the basic concepts, developments and the biomedical applications of nanobiosensors.

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Tailoring self-assembled monolayers at the electrochemical interface

Cited by 8 publications

References 39 publications

The Formation and Organization of Self-Assembled Monolayer (SAM) for Escherichia coli Detection: A Review

The Formation and Organization of Self-Assembled Monolayer (SAM) for Escherichia coli Detection: A Review

An integrated microfluidic system for rapid HbA1c and glucose measurement

Biomedical applications of nanobiosensors: the state-of-the-art

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