Tailoring Optical Gradient Force and Optical Scattering and Absorption Force

Du, Junjie; Yuen, Chi Hong; Li, Xiao; Ding, Kun; Du, Guiqiang; Lin, Zhifang; Chan, Che Ting; Ng, Jack

doi:10.1038/s41598-017-17874-1

Cited by 55 publications

(33 citation statements)

References 51 publications

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“…Even though the term "gradient force" is traditionally associated with the electric dipole and paraxial field approximations, we borrow this expression and identify the anti-symmetric force part as such. The Fourier treatment recently presented in [44,45] generalizes this decomposition to all of space, albeit in a numerically more demanding fashion.…”

Section: Optical Forces In a Focused Gaussian Beammentioning

confidence: 99%

Directional scattering and multipolar contributions to optical forces on silicon nanoparticles in focused laser beams

Länk¹,

Johansson²,

Käll³

2018

Opt. Express

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Nanoparticles made of high index dielectric materials have seen a surge of interest and have been proposed for various applications, such as metalenses, light harvesting and directional scattering. With the advent of fabrication techniques enabling colloidal suspensions, the prospects of optical manipulation of such nanoparticles becomes paramount. High index nanoparticles support electric and magnetic multipolar responses in the visible regime and interference between such modes can give rise to highly directional scattering, in particular a cancellation of back-scattered radiation at the first Kerker condition. Here we present a study of the optical forces on silicon nanoparticles in the visible and near infrared calculated using the transfer matrix method. The zero-backscattering Kerker condition is investigated as an avenue to reduce radiation pressure in an optical trap. We find that while asymmetric scattering does reduce the radiation pressure, the main determining factor of trap stability is the increased particle response near the geometric resonances. The trap stability for non-spherical silicon nanoparticles is also investigated and we find that ellipsoidal deformation of spheres enables trapping of slightly larger particles.

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Section: Optical Forces In a Focused Gaussian Beammentioning

confidence: 99%

Directional scattering and multipolar contributions to optical forces on silicon nanoparticles in focused laser beams

Länk¹,

Johansson²,

Käll³

2018

Opt. Express

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“…A typical force-displacement relationship in an optical trap is illustrated in Figure 2 [47]. Detailed physical models for quantitative and qualitative description of optical forces both in geometric optics regime and under electromagnetic theory have been well established and can be found in literature [6,42,[44][45][46][47][48]. Concerning the trapping of biological objects, the optical forces exerted on optically active particles have been analytically modeled with T-matrix formalism [49].…”

Section: Physical Interpretation Of Optical Trappingmentioning

confidence: 99%

Optical Tweezers in Studies of Red Blood Cells

Zhu

Avsievich

Попов

et al. 2020

Cells

102

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Optical tweezers (OTs) are innovative instruments utilized for the manipulation of microscopic biological objects of interest. Rapid improvements in precision and degree of freedom of multichannel and multifunctional OTs have ushered in a new era of studies in basic physical and chemical properties of living tissues and unknown biomechanics in biological processes. Nowadays, OTs are used extensively for studying living cells and have initiated far-reaching influence in various fundamental studies in life sciences. There is also a high potential for using OTs in haemorheology, investigations of blood microcirculation and the mutual interplay of blood cells. In fact, in spite of their great promise in the application of OTs-based approaches for the study of blood, cell formation and maturation in erythropoiesis have not been fully explored. In this review, the background of OTs, their state-of-the-art applications in exploring single-cell level characteristics and bio-rheological properties of mature red blood cells (RBCs) as well as the OTs-assisted studies on erythropoiesis are summarized and presented. The advance developments and future perspectives of the OTs’ application in haemorheology both for fundamental and practical in-depth studies of RBCs formation, functional diagnostics and therapeutic needs are highlighted.

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“…The CSCs within tumor bulk display the capacity to self-renew, differentiate, and give rise to a new tumor (Visvader and Lindeman 2012 ). Recently, lots of surface markers of CSCs have been identified, including CD133, CD13, CD24, ALDH1A1, CD44, and so on (Henderson et al 2018 ; Li et al 2018 ; Marotta et al 2011 ; Organista-Nava et al 2014 ; Yang et al 2014 ). It is still a general strategy to isolate CSCs by FACS and to examine their biological features.…”

Section: Biological Characteristics and Study Strategies Of Cscsmentioning

confidence: 99%

Cancer stem cells and tumorigenesis

Zhu

Fan

2018

Biophys Rep

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Cancer is one of the most serious diseases all over the world, and the cancer stem cell (CSC) model accounts for tumor initiation, metastasis, drug resistance, and relapse. The CSCs within tumor bulk have the capacity to self-renew, differentiate, and give rise to a new tumor. The self-renewal of CSCs is precisely regulated by various modulators, including Wnt/β-catenin signaling, Notch signaling, Hedgehog signaling, transcription factors, chromatin remodeling complexes, and non-coding RNAs. CSCs reside in their niches that are also involved in the self-renewal maintenance of CSCs and protection of CSCs from chemotherapy, radiotherapy, and even endogenous damages. Moreover, CSCs can also remodel their niches to initiate tumorigenesis. The mutual interactions between CSCs and their niches play a critical role in the regulation of CSC self-renewal and tumorigenesis as well. Many surface markers of CSCs have been identified, and these markers become first choices for CSC targeting. Due to heterogeneity and plasticity, targeting CSCs is still a big challenge for tumor elimination. In this review, we summarize recent progresses on the biological features of CSCs and targeting strategies against CSCs.

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Tailoring Optical Gradient Force and Optical Scattering and Absorption Force

Cited by 55 publications

References 51 publications

Directional scattering and multipolar contributions to optical forces on silicon nanoparticles in focused laser beams

Directional scattering and multipolar contributions to optical forces on silicon nanoparticles in focused laser beams

Optical Tweezers in Studies of Red Blood Cells

Cancer stem cells and tumorigenesis

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