Tailor-made gold nanostar colorimetric detection determined by morphology change and used as an indirect approach by using hydrogen peroxide to determine glucose concentration

Mulder, Danielle Wingrove; Phiri, Masauso Moses; Vorster, Barend Christiaan

doi:10.1016/j.sbsr.2019.100296

Cited by 14 publications

(23 citation statements)

References 24 publications

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“…The nanostars were synthesised as described above (AuNs synthesis method) with the following modifications that were previously described for functionalisation with glucose oxidase [37]: Once the nanostars were synthesised by the AuNs method. Capping was performed with a PVP solution diluted to 2.5 mM and the incubation time was shortened to 90 min.…”

Section: Methodsmentioning

confidence: 99%

Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection

2019

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Diabetes Mellitus is a growing global concern. The current methods used to detect glycated haemoglobin are precise, however, utilise expensive equipment, reagents and consumables. These are luxuries which rural communities cannot access. The nanotechnology methods which have been developed for glycated haemoglobin detection are predominantly electrochemically based, have complicated lengthy fabrication processes and utilise toxic chemicals. Here a fructosyl amino acid oxidase gold nanostar biosensor has been developed as a potential future point of care biosensor candidate for glycated haemoglobin detection. The workup done on this biosensor showed that it was able to give a spectrophotometric readout and colorimetric result with naked eye detection in blank serum spiked with fructosyl valine.

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Section: Methodsmentioning

confidence: 99%

Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection

2019

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“…By choosing the appropriate method and experimental parameters for the synthesis it is possible to control shapes and obtain spheres (AgNPhs), cubes (AgNCs), stars (AgNSs) and rods (AgNRs) [ 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 ]. Some examples with TEM images showing AgNPs with different geometries and shapes are presented in Figure 1 [ 68 , 81 , 88 ].…”

Section: Agnps Preparation and Use For Water Pollution Monitoring mentioning

confidence: 99%

“…In fact, by changing the type of surface functionalization and by choosing a specific ligand, it is possible to make particles selective to a particular analyte, and by optimizing the degree of surface functionalization, their sensitivity can be improved. The main chemical molecules and capping agents used for direct functionalization of AgNPs during the synthesis of different morphologies are reported in Table 1 , together with dimension and applications for water pollution monitoring [ 26 , 54 , 72 , 73 , 74 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 ].…”

Section: Agnps Preparation and Use For Water Pollution Monitoring mentioning

confidence: 99%

“…The large extinction background can be attributed to the absorption and scattering emissions produced by the different morphologies of all the existing NPs, integrated by AgNSs bearing different numbers of arms and having different tip sharpness. The mixture of all these factors leads to very different LSPR in the suspension, since a wide range of wavelengths in the visible and near-IR ranges can be covered with various AgNSs shapes and dimensions [86][87][88][89][90][91][92][93].…”

Section: Introductionmentioning

confidence: 99%

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Silver Nanoparticles for Water Pollution Monitoring and Treatments: Ecosafety Challenge and Cellulose-Based Hybrids Solution

et al. 2020

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Silver nanoparticles (AgNPs) are widely used as engineered nanomaterials (ENMs) in many advanced nanotechnologies, due to their versatile, easy and cheap preparations combined with peculiar chemical-physical properties. Their increased production and integration in environmental applications including water treatment raise concerns for their impact on humans and the environment. An eco-design strategy that makes it possible to combine the best material performances with no risk for the natural ecosystems and living beings has been recently proposed. This review envisages potential hybrid solutions of AgNPs for water pollution monitoring and remediation to satisfy their successful, environmentally safe (ecosafe) application. Being extremely efficient in pollutants sensing and degradation, their ecosafe application can be achieved in combination with polymeric-based materials, especially with cellulose, by following an eco-design approach. In fact, (AgNPs)–cellulose hybrids have the double advantage of being easily produced using recycled material, with low costs and possible reuse, and of being ecosafe, if properly designed. An updated view of the use and prospects of these advanced hybrids AgNP-based materials is provided, which will surely speed their environmental application with consequent significant economic and environmental impact.

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“…due to the generation of reactive oxygen species (ROS), 37,38 which are known to have etching or oxidizing effects on AuNSs. [39][40][41] One should also be aware that metallic nanoparticles themselves can mediate an excessive production of cellular ROS, resulting in oxidative cellular stress and leading to cell toxicity. 42 We focus the discussion here on the stability of pH SERS probes against oxidizing agents, while NP-induced cell toxicity will be discussed below.…”

Section: Stability Of Auns-4mba-pa Nanosensormentioning

confidence: 99%

Live-Cell Surface-Enhanced Raman Spectroscopy Imaging of Intracellular pH: From Two Dimensions to Three Dimensions

et al. 2020

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Visualization of intracellular pH (i-pH) using surface-enhanced Raman spectroscopy (SERS) plays an important role toward understanding cellular processes including their interactions with nanoparticles. However, conventional two-dimensional (2D) SERS imaging often fails to take into consideration changes occurring in the whole cell volume. We therefore aimed at obtaining a comprehensive i-pH profile of living cells by means of three-dimensional (3D) SERS imaging, thereby visualizing dynamic i-pH distribution changes in a single cell. We devised herefore a biocompatible and highly stable SERS pH probe, comprising plasmonic gold nanostars functionalized with a pH-sensitive Raman reporter tag-4-mercaptobenzoic acid (4MBA)and protected by a cationic biocompatible polymer, poly-L-arginine hydrochloride (PA). The positively-charged PA coating plays a double role of enhancing cell uptake and providing chemical and colloidal stability in cellular environments. The SERS-active pH probe allowed visualization of local changes in i-pH, such as acidification during NP endocytosis. We provide evidence of i-pH changes during NP endocytosis via high-resolution 3D SERS imaging, thereby opening new avenues toward the application of SERS to intracellular studies.

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Tailor-made gold nanostar colorimetric detection determined by morphology change and used as an indirect approach by using hydrogen peroxide to determine glucose concentration

Cited by 14 publications

References 24 publications

Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection

Gold Nanostar Colorimetric Detection of Fructosyl Valine as a Potential Future Point of Care Biosensor Candidate for Glycated Haemoglobin Detection

Silver Nanoparticles for Water Pollution Monitoring and Treatments: Ecosafety Challenge and Cellulose-Based Hybrids Solution

Live-Cell Surface-Enhanced Raman Spectroscopy Imaging of Intracellular pH: From Two Dimensions to Three Dimensions

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