T. Mentagrophytes and T. Mentagrophytes Var. Quinckeanum Infections of South Australian Mice*

Abstract

In 1917 Paul published in the Medical Journal of Australia a short paper entitled " A ringworm epidemic presenting a new type of fungus ". Because of its unusual epidemiological and mycological interest this paper is quoted iu full: " Eecently there passed over certain districts of New South Wales a plague of mice, which advanced with the rapidity of an invading army, leaving in their train signs of great destruction and devastation. Their food supplies were drawn from huge stacks of wheat, accumulated owing to the lack of freight. As a result much of the wheat had to be rebaggcd and shifted, and many of those handling it, became infected with a cutaneous eruption, which was diagnosed as ringworm. There was ample evidence that the mice were the causative agent in this spread, for many were seen with patches almost denuded of hair. As the occurrence of a similar epidemic is remote, and as the clinical, and more especially the cultural aspects offer certain peculiarities, as well as the source of the disease, for mice are occasionally the carriers of favus, it seemed to me that it m.ay be of interest to record cases characteristic of this epidemic. The eruptions occurred mostly on the exposed parts, an,d on the hair region of the face numerous and extensive areas of pustulation, the so-called multiple kerion, presented themselves. The case about to be described is typical of the lesions as they affect the glabrous skin. The forearms were the regions involved, and the history given by the patient was that he had been handling wheat some two and a half months ago, but had only observed the lesion fourteen days before seeking medical attention. He states that in appearauce it first resembled goose-skin without any redness, but that later erythema manifested itself, and the lesion spread in a circular mauner. Pruritus was complained of, beiug more noticeable at night-time. On examination lesions in various stages of development were present, a striking feature of the early patches being the rounded, and sharply circumscribed border, in which were scattered on an crythematous base, discrete vesicles, vesico-pustulcs, and pustules, but in these dcsquamation was absent. The more advanced patches showed another phase in which there was a somewhat striking resemblance to chronic eczema. In these, the periphery was not sharply circumscribed as in the earlier lesions, the vesicles and pustules had disappeared, and outlying papules or papulo-vesicles were to be observed, as in chronic eczema, which was also simulated by the surface exhibiting a dry scaly roughness.

Epidemiology, Health Effects and Treatment of Cutaneous Mycoses of Goat and Sheep from Some Eastern States of Nigeria

“…Isolates were identified on the basis of a detailed study of their gross and microscopic morphology and by comparison with standard descriptions [13]. Hair penetration test [14] was used for identification of T. Mentagrophytes. Germ tube test according to [15] was used for identification of Candida albicans.…”

Topical Treatment of Dermatophytic Lesion on Mice (Mus musculus) Model

“…Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum spp, Epidermophyton spp [1] and remains a common public health problem, especially in tropical countries such as India [2]. Trichophyton mentagrophytes is considered as a zoophilic and anthrophilic dermatophyte [3][4][5][6] which causes hair, skin and nail infections in humans.…”