t-communicating iso-array P system

Annadurai, S.; Kalyani, T.; Dare, V. R.; Thomas, D. G.

doi:10.1109/nabic.2009.5393675

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…[36] In previous studies, it was shown that diabetes negatively affects the antioxidant systems of erythrocytes. [41,42] In this study, we also showed the decreasing levels of erythrocyte GSH and GSH-Px activities in diabetic mice.…”

Section: Discussionsupporting

confidence: 66%

The susceptibility to autoxidation of erythrocytes in diabetic mice: Effects of melatonin and pentoxifylline

Şekeroğlu

Huyut

Çokluk

et al. 2017

J Biochem & Molecular Tox

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Oxidative stress had a great importance in development of complications in diabetes. We investigated effects of melatonin and pentoxifylline in diabetic mice. Swiss albino mice (n = 40) were divided into four groups: alloxan-induced diabetes mellitus (DM), alloxan-induced diabetes with melatonin supplementation (DM + MLT), alloxan-induced diabetes with pentoxifylline supplementation (DM + PTX), and control. Glutathione-peroxidase (GSH-Px) activity, malondialdehyde (MDA) and reduced glutathione (GSH) levels, and susceptibility to oxidation of erythrocytes were measured. MDA levels were higher than control in the DM and DM + MLT. The DM had more MDA level than the DM + MLT and DM + PTX (P < 0.001). After in vitro oxidation, MDA levels of all groups were found higher than the control. However, they were significantly lower than the DM in DM + PTX and DM + MLT (P < 0.001). Although GSH levels of the DM and DM + PTX were less than the control, GSH-Px activity of the DM was lower than the control and DM + PTX (P < 0.05). We suggest that there is increased oxidative stress and compromised antioxidant status of erythrocytes in diabetes; however, it can be effectively prevented by melatonin or pentoxifylline supplementation.

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Section: Discussionsupporting

confidence: 66%

The susceptibility to autoxidation of erythrocytes in diabetic mice: Effects of melatonin and pentoxifylline

Şekeroğlu

Huyut

Çokluk

et al. 2017

J Biochem & Molecular Tox

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show abstract

“…[12] In addition, oral administration of naringenin ameliorated hyperglycemia, oxidative stress, and inflammatory responses in diabetic animal models. [13,14] However, protective effects and underlying mechanisms, by which naringin could counteract β-cell failure in type 1 diabetes (T1D), are yet to be elucidated. Therefore, in this study, we aimed to study the molecular mechanisms of naringin, with regard to regulation of the intrinsic and extrinsic pathways of β-cell apoptosis, as well as oxidative stress, in STZ-induced insulin-deficient diabetic mice.…”

Section: Introductionmentioning

confidence: 99%