Syzigium cumini and Mangifera indica Seed Extracts: In Vitro Assessment for Antibacterial Activity Alone and in Combination with Antibiotics against Clinical Bacteria

Das, Malay Kumar; Shyamapada, M

doi:10.4172/2329-8731.1000129

Cited by 4 publications

(1 citation statement)

References 27 publications

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“…Un estudio realizado con extractos etanólicos de la semilla de mango frente a E. coli, S. aureus y K. pneumoniae, además de efectos sinérgicos con antibióticos como ampicilina, ciprofloxacina y meticilina, frente a los 3 microorganismos mencionados (Das, & Mandal, 2016).…”

Section: Introductionunclassified

Actividad antimicrobiana de extractos hidroalcohólicos de hojas de dos variedades de Mangifera indica L

Carrillo-Tomalá

Díaz-Torres

Guerra-Guamán

et al. 2020

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El objetivo de este trabajo fue evaluar la actividad antimicrobiana de extractos hidroalcohólicos (90% y 50%) de la variedad Tommy Atkins y extracto hidroalcohólico (50%) de la variedad Edward, seleccionados por su alto contenido de compuestos fenólicos, anteriormente publicado. Los extractos fueron obtenidos por maceración, digestión y ultrasonido. La actividad antimicrobiana se evalúo mediante los métodos Kirby Bauer y Kirby Bauer modificado; las cepas utilizadas fueron Pseudomona aeuroginosa (ATCC 27853), Staphylococcus aureus (ATCC 29213), Salmonella Typhimurium (ATCC 14028), Escherichia coli (ATCC 25922) y Enterococcus faecalis (ATCC 29212), ajustándose las suspensiones a turbidez 0.5 en escala McFarland. La mayor actividad antimicrobiana se evidencia frente a P. aeruginosa y S. aureus; los extractos de la variedad Tommy Atkins mostraron mayor actividad antimicrobiana, encontrándose halos de inhibición entre 10 y 15 mm según la bacteria. El método Kirby Bauer modificado mostró mayor efectividad. Se concluye que todas las cepas estudiadas presentaron sensibilidad frente a los extractos, siendo S. aureus y P. aeruginosa las más sensibles.

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Section: Introductionunclassified

Actividad antimicrobiana de extractos hidroalcohólicos de hojas de dos variedades de Mangifera indica L

Carrillo-Tomalá

Díaz-Torres

Guerra-Guamán

et al. 2020

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Antibacterial Activity of Endostemon tereticaulis (Poir.) M. Ashby Essential Oil and Ethanolic Extract Against Resistant Pathogenic Bacteria

Abba

Romane

Ilagouma

2020

Natural Product Communications

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Endostemon tereticaulis (poir.) M.Ashby is a species of the Lamiaceae family present in Niger. This plant is used in traditional medicine due to its various biological potentialities. The present study investigated the chemical composition of the essential oil and the antibacterial activity of the essential oil and ethanolic extract of Endostemon tereticaulis against resistant pathogenic bacteria. Gas chromatography-mass spectrometry analysis of the essential oil led to the identification of 43 compounds representing 99.55% of the total essential oil. The major components were caryophyllene oxide (15.17%) followed by α-humulene (13.96%), α-copaene (11.75%), ( E)-β-caryophyllene (8.44%), and δ-cadinene (6.78%). The antibacterial activity was tested against multiresistant Acinetobacter baumannii P1483, Salmonella spp. H1548, extended-spectrum β-lactamase- Escherichia coli Bu8566, Enterobacter cloacae Bu147, Proteus mirabilis Bu190 , Pseudomonas aeruginosa (ATCC 27853), Klebsiella pneumoniae (ATCC 700603), Escherichia coli (ATCC 25922), Enterococcus faecium H3434, methicillin-resistant Staphylococcus aureus P1123, and Staphylococcus aureus (ATCC 25923). The antibacterial assays revealed that the essential oil was more active than the ethanolic extract against the studied bacteria with minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values ranging from 0.06 to 2 mg/mL. Also, the ethanolic extract was effective against the bacteria tested with MIC and MBC values ranging from 0.12 to 3 mg/mL. This study showed that Endostemon tereticaulis essential oil is rich in bioactive compounds. Ethanolic extract and essential oil exhibited potential antibacterial activity. These results provide a scientific basis for the use of this plant in traditional medicine. The current study described for the first time the antibacterial activity of Endostemon tereticaulis.

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Highlights on the alternatives to antibiotic therapy against bacterial infection

Sircar

Mandal

2021

J. Drug Delivery Ther.

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The antibiotic resistance among gram-positive and gram-negative pathogenic bacteria is of global health concern. This has prompted the development of new effective drugs. But the discovery and development of new drugs is slow, and the emergence of resistance to such new drugs, on the other hand, is rapid as well as continuous among the bacteria. Therefore, in tackling the emergence of antibiotic resistant pathogenic bacteria finding alternative ways is vital. This communication, based on the published scientific data, summarizes the antibacterial capacity of some naturally derived agents such as honey, phytocomponents, probiotics, and antimicrobial peptides that might bring new essence in biomedicine. Keywords: Bacterial resistance, alternative therapeutics, honey, phytomedicine, probiotics, antimicrobial peptides.

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Syzigium cumini and Mangifera indica Seed Extracts: In Vitro Assessment for Antibacterial Activity Alone and in Combination with Antibiotics against Clinical Bacteria

Cited by 4 publications

References 27 publications

Actividad antimicrobiana de extractos hidroalcohólicos de hojas de dos variedades de Mangifera indica L

Actividad antimicrobiana de extractos hidroalcohólicos de hojas de dos variedades de Mangifera indica L

Antibacterial Activity of Endostemon tereticaulis (Poir.) M. Ashby Essential Oil and Ethanolic Extract Against Resistant Pathogenic Bacteria

Highlights on the alternatives to antibiotic therapy against bacterial infection

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