Systemic pathological alterations caused by Philodryas patagoniensis colubrid snake venom in rats

Antitumoral and antioxidant effects of a hydroalcoholic extract of cat's claw (Uncaria tomentosa) (Willd. Ex Roem. & Schult) in an in vivo carcinosarcoma model

“…Elevated plasmatic levels of GGT, ALT and AST in control rats indicate that hepatic functions are modified by W-256 tumor. Increased plasma levels of both ALT and AST are generally regarded as important indicators of cellular hepatic lesions (Peichoto et al, 2006), once alterations in hepatocyte function or membrane permeability can result in enzyme extravasation to plasma. However, UT treatment was able to reduce significantly AST plasmatic level.…”

Systemic pathological effects induced by cobra (Naja naja) venom from geographically distinct origins of Indian peninsula

“…The histopathological studies were carried out as described earlier (Peichoto et al, 2006). Three groups of mice (N ¼ 9 in each group) were injected (i.p.)…”

Histopathological Changes in Brain, Kidney and Liver of Mice following Intramuscular Administration of Krait Venom

“…However, since snake venom is rich in neurotoxins significant microscopical changes are likely to be present in the brain tissue. Multiple small foci of haemorrhages and congestion of blood vessels have been reported following administration of collubrid snake venom to rats which was more marked with intravenous injection of venom (Peichoto et al, 2006). Apoptosis of Schwann cells following intramuscular injection of beta bungarotoxin has been demonstrated in chick embryos (Ciutat et al, 1996).…”