Systemic disorders that affect gastrointestinal motility

Lee, Yeong Yeh; Haque, Mohammad Majharul; Lawenko, Rona Marie; Sharma, Amol

doi:10.1016/b978-0-12-813037-7.00043-1

Cited by 4 publications

(2 citation statements)

References 57 publications

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“…In Malaysia, DGBIs are perhaps the most common clinical consults in gastroenterology practice and patients are often affected not just by symptoms but by poor quality of life and associated psychological illnesses including anxiety and depression ( 13 ). Patients are often investigated with many tests but at the end they may be told to be normal.…”

Section: Practice In Malaysiamentioning

confidence: 99%

The Brain-Gut Clinic in Hospital Universiti Sains Malaysia: Pioneering New Service to Advance Neuro-Gastroenterology and Motility in Malaysia

Yeong Yeh,

Izham,

Mohd Zulkifly

et al. 2023

MJMS

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Neurogastroenterology and motility is a new but advanced subspecialty within gasteroenterology that cater to difficult, persistent and refractory gut-brain symptoms. Hospital USM has the country’s first and new state-of-the art motility lab that was recently launched on the 25 May 2023, and is covered in nationwide media. Another first is the Brain-Gut Clinic, established on the 16 November 2022. The clinic is a new concept that builds on unique multiple disciplines in relation to the gut-brain axis. It is hoped that there will be more awareness on the existence of neurogastroenterology and motility among doctors and community, and that more research can be forthcoming to reduce the disease burden.

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Section: Practice In Malaysiamentioning

confidence: 99%

The Brain-Gut Clinic in Hospital Universiti Sains Malaysia: Pioneering New Service to Advance Neuro-Gastroenterology and Motility in Malaysia

Yeong Yeh,

Izham,

Mohd Zulkifly

et al. 2023

MJMS

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“…A thorough medication history can identify exacerbating medications, opioids and anti‐cholinergic medications. Secondary constipation may also be a result of diabetes mellitus, chronic renal disease, dehydration, Parkinson's disease, Ehlers‐Danlos syndrome or other connective tissue disorders 3,30,31 …”

Section: Diagnostic Toolsmentioning

confidence: 99%

Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders

Sharma

Rao

Kearns

et al. 2021

Aliment Pharmacol Ther

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Summary Background Chronic constipation is a common, heterogeneous disorder with multiple symptoms and pathophysiological mechanisms. Patients are often referred to a gastroenterology provider after laxatives fail. However, there is limited knowledge of the spectrum and management of constipation disorders. Aim To discuss the latest understanding of the spectrum of constipation disorders, tools for identifying a pathophysiologic‐based diagnosis in the specialist setting, treatment options and the patient's perspective of constipation. Methods Literature searches were conducted using PubMed for constipation diagnostic criteria, diagnostic tools and approved treatments. The authors provided insight from their own practices. Results Clinical assessment, stool diaries and Rome IV diagnostic criteria can facilitate diagnosis, evaluate severity and distinguish between IBS with constipation, chronic idiopathic constipation and dyssynergic defecation. Novel smartphone applications can help track constipation symptoms. Rectal examinations, anorectal manometry and balloon expulsion, assessments of neuromuscular function with colonic transit time and colonic manometry can provide mechanistic understanding of underlying pathophysiology. Treatments include lifestyle and diet changes, biofeedback therapy and pharmacological agents. Several classes of laxatives, as well as prokinetic and prosecretory agents, are available; here we describe their mechanisms of action, efficacy and side effects. Conclusions Constipation includes multiple overlapping subtypes identifiable using detailed history, current diagnostic tools and smartphone applications. Recognition of individual subtype(s) could pave the way for optimal, evidence‐based treatments by a gastroenterology provider.

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Gastric AA amyloidosis secondary to chronic infection presenting with hematemesis: a case report

Huang

Nasir

Challa

et al. 2020

Clin J Gastroenterol

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Systemic disorders that affect gastrointestinal motility

Cited by 4 publications

References 57 publications

The Brain-Gut Clinic in Hospital Universiti Sains Malaysia: Pioneering New Service to Advance Neuro-Gastroenterology and Motility in Malaysia

The Brain-Gut Clinic in Hospital Universiti Sains Malaysia: Pioneering New Service to Advance Neuro-Gastroenterology and Motility in Malaysia

Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders

Gastric AA amyloidosis secondary to chronic infection presenting with hematemesis: a case report

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