Gastric AA amyloidosis secondary to chronic infection presenting with hematemesis: a case report

Huang, Yuting; Nasir, Salahuddin; Challa, Suryanarayana Reddy; Peng, Chung Kang; Stashek, Kristen; Fanaroff, Rachel; Hu, Shien

doi:10.1007/s12328-020-01211-7

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…AA amyloidosis can have different etiologies. A major cause is chronic infection [458,459]. The amyloid deposits that develop as a result of chronic infections may occur generalized or localized [459].…”

Section: Aa Amyloidmentioning

confidence: 99%

“…The most effective therapy is to eliminate the cause of chronically elevated SAA levels because treating the underlying disease can lead to subsequent reductions in acute-phase protein production, including the circulating serum SAA levels. However, there are no common therapeutic strategies for AA amyloidosis due to its diverse etiology [458].…”

Section: Aa Amyloidmentioning

confidence: 99%

See 1 more Smart Citation

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

2022

View full text Add to dashboard Cite

Uveitis is a sight-threatening eye disease in equids known worldwide that leads to considerable pain and suffering. By far the most common type of uveitis in Germany and neighboring countries is classical equine recurrent uveitis (ERU), which is caused by chronic intraocular leptospiral infection and is the main cause of infectious uveitis in horses. Other infectious causes are extremely rare and are usually clinically distinguishable from ERU. ERU can be treated very effectively by vitreous cavity lavage (vitrectomy). For proper indications of this demanding surgery, it is necessary to differentiate ERU from other types of uveitis in which vitrectomy is not helpful. This can be conducted on the basis of anamnesis in combination with ophthalmologic findings and by aqueous humor examination. During vitrectomy, vitreous material is obtained. These vitreous samples have historically been used for numerous etiologic studies. In this way, a chronic intraocular leptospiral infection has been shown to be the cause of typical ERU and, among other findings, ERU has also been recognized as a biofilm infection, providing new insights into the pathogenesis of ERU and explaining some thus far unexplainable phenomena of ERU. ERU may not only have transmissible aspects to some types of uveitis in humans, but may also serve as a model for a spontaneously occurring biofilm infection. Vitreous material obtained during therapeutically indicated vitrectomy can be used for further studies on in vivo biofilm formation, biofilm composition and possible therapeutic approaches.

show abstract

Section: Aa Amyloidmentioning

confidence: 99%

Section: Aa Amyloidmentioning

confidence: 99%

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

2022

View full text Add to dashboard Cite

show abstract

Gastric and Duodenal Amyloidosis in an Hiv-Infected Patient: A Case Report and a Literature Review

Губергріц¹,

Mozhyna²,

Tsys

et al. 2023

Wiad Lek

View full text Add to dashboard Cite

We report the case of a 38-year-old female with gastrointestinal amyloidosis who presented with acute abdominal pain. The computed tomography scan showed that the patient had generalized lymphadenopathy. This clinical picture with absolute leukocytosis was interpreted as an acute secondary bacterial process of unspecified etiology with generalized lymphadenopathy. The patient was administered a broad-spectrum antibacterial drug and detoxication therapy. The upper endoscopy revealed bleeding of unknown origin. After a 2-day conservative hemostatic therapy, gastric tumor involvement was suggested during control endoscopy. The human immunodeficiency virus (HIV) antibodies were found with the following confirmation of their specificity by immunoblotting. Histopathological study of the biopsy specimens made it possible to diagnose gastrointestinal AA/AL-amyloidosis complicated by gastrointestinal bleeding.

show abstract

Gastric AA amyloidosis secondary to chronic infection presenting with hematemesis: a case report

Cited by 2 publications

References 10 publications

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis

Gastric and Duodenal Amyloidosis in an Hiv-Infected Patient: A Case Report and a Literature Review

Contact Info

Product

Resources

About