“…EV70 can also cause neurological complications (1:10,000) including asymmetrical flaccid motor paralysis (radiculomyelitis) similar to poliomyelitis and cranial nerve palsies as well as a dysautonomic feature [4][5][6][7][8] . Natural and experimental EV70 infection is generally localized to the superficial conjunctival epithelial cell layer (i.e., conjunctivitis) and corneal epithelium (i.e., keratitis) [9,10] and results in AHC. Although it cannot infect and replicate in all kinds of human cells, EV70 has been found to be able to infect and replicate in a broad range of human cells including leukocyte cells (A2.01, Daudi, HL60, Jurkat, Raji, THP-1 and U937) [11] and human eye cells such as HCC cell [12] , SRA01/04 cells [13] , human retina and retina pigment epithelial cells (unpublished).…”