Systemic Administration of Rosmarinus officinalis Attenuates the Inflammatory Response Induced by Carrageenan in the Mouse Model of Pleurisy

Rosa, Júlia Salvan da; Facchin, B.; Bastos, Juliana; Siqueira, Mariana Alves de Sá; Micke, Gustavo Amadeu; Dalmarco, Eduardo Monguilhott; Pizzolatti, Moacir Geraldo; Fröde, Tânia Sílvia

doi:10.1055/s-0033-1351018

Cited by 23 publications

(9 citation statements)

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“…Controlling the release of mediators in the inflammatory process is the main objective of anti-inflammatory drugs [ 100 ]. Pain and inflammation are related to wound healing and production of free radicals which could extend the inflammation process [ 101 ].…”

Section: Anti-inflammatory and Analgesic Activitiesmentioning

confidence: 99%

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity

et al. 2018

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The worldwide interest in the use of medicinal plants has been growing, and its beneficial effects being rediscovered for the development of new drugs. Based on their vast ethnopharmacological applications, which inspired current research in drug discovery, natural products can provide new and important leads against various pharmacological targets. This work pioneers an extensive and an updated literature review on the current state of research on Rosmarinus officinalis L., elucidating which compounds and biological activities are the most relevant. Therefore, a search was made in the databases PubMed, ScienceDirect and Web of Science with the terms ‘rosemary’, ‘Rosmarinus officinalis’, ‘rosmarinic acid’ ‘carnosol’ and ‘carnosic acid’, which included 286 articles published since 1990 about rosemary's pharmacological activities and their isolated compounds. According to these references, there has been an increasing interest in the therapeutic properties of this plant, regarding carnosic acid, carnosol, rosmarinic acid and the essential oil. The present manuscript provides an updated review upon the most reported activities on R. officinalis and its active constituents.

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Section: Anti-inflammatory and Analgesic Activitiesmentioning

confidence: 99%

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity

et al. 2018

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“…The traditional use of Rosmarinus officinalis L. (Lamiaceae family) as an effective remedy for pain relief and inflammatory disorders is also well documented. Rosemary extracts proved to alleviate rheumatism and asthma [6], acnes [7], chronic liver disease [8], inflammatory bowel disease [9], neuro-inflammation [10] and arthritis [11,12].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant–Anti-Inflammatory Evaluation of a Polyherbal Formula

et al. 2022

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Most disease—both acute and chronic—results from inflammation, and reactive oxygen species (ROS) are considered some of the strongest stimuli of inflammation. Many studies reported the traditional use of herbal species for treating inflammation, especially when ROS are involved. The present study aims to demonstrate the antioxidant–anti-inflammatory effects of a patented preparation based on Populus nigra and Rosmarinus officinalis extracts and to highlight its applicative potential; the formula was characterized by HPTLC and HPLC and in-vitro studies were conducted on TNF-α-stimulated HUVECs. The antioxidant activity of the formula was determined by DPPH assay and the phosphomolybdenum method; to assess in-vivo anti-inflammatory activity, a rat paw edema model was used; the formula contains high amounts of polyphenols. It exhibited scavenging activity of 50–85% at 1–10 mg/mL, it inhibited nitrite production and ICAM-1 expression in TNF-α-stimulated endothelial cell cultures dose-dependently, at a maximum of 58.7% at the maximum dose administered and exerted an obvious anti-inflammatory effect in vivo, settling early and decreasing at 180 min; a new herbal bioactive product was presented with promising therapeutic potential that can be an adjunct to conventional therapies for diseases based on oxidative stress and inflammation.

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“…This paintings expands the price of destiny research on consequences of low doses of rosemary on memory and cognition. [2] more specific facts regarding in vitro and in vivo experimental studies is displayed within the tables in Supplementary material [10] Rosemary Extract for Skin Prevents ageing of skin because it contains certainly powerful antioxidants, rosemary oil strengthens the capillaries and helps to gradual the results of aging on pores and skin. It additionally tightens sagging and free skin to help it look firmer and more elastic.…”

Section: Anti-tumor Activitymentioning

confidence: 99%

review on “pharmacological, phytochemical, and medicinal properties of rosmarinus officinalis (Rosemary)”

Chatterjee¹,

Tamta²,

Mukopadayay³

2022

ijhs

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International use of natural medicinal drugs has been increasing in the last few centuries. In developing international locations, many people were using other natural remedies to meet their fitness care desires. On the opposite facet, developing countries had to make a bigger interest in medicinal herbs. The most vital difficulty in natural medicine is that their market is inadequate regulated, and very restricted statistics have been presented regarding the safety and efficacy of medicinal herbs. there's almost no side impact within the use of herbal merchandise. natural medicines provide harmless and efficient use.Rosemary consists huge form of phytochemicals along with the impact of dietary antioxidative and chemopreventive rosemary phytochemical on the feature of human drug efflux transporter Pglycoprotein and multidrug resistance protein 1 .The effect of natural phytochemical found in rosemary inclusive of carnosic acid , carnosol , rosemarinic acid , and ursolic acid and different many additives. Rosemary appears to boom blood circulation while applied to the scalp, which would possibly assist hair follicles develop. Rosemary extract may additionally help guard the pores and skin from solar harm.

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Systemic Administration of Rosmarinus officinalis Attenuates the Inflammatory Response Induced by Carrageenan in the Mouse Model of Pleurisy

Cited by 23 publications

References 50 publications

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity

Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity

Antioxidant–Anti-Inflammatory Evaluation of a Polyherbal Formula

review on “pharmacological, phytochemical, and medicinal properties of rosmarinus officinalis (Rosemary)”

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