Systematic review with meta-analysis of partial enteral nutrition for the maintenance of remission in Crohn’s disease

Yang, Hongsheng; Feng, Rui; Li, Tong; Xu, Song; Hao, Xiuxue; Qiu, Yun; Chen, Minhu

doi:10.1016/j.nutres.2020.06.006

Cited by 14 publications

(11 citation statements)

References 42 publications

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“…Changes in microbiota composition have been seen to be rapid, emerging even within one week from receiving EN treatment [ 107 ]. EN seems to lower microbial diversity, SCFA concentrations, and Faecalibacterium prausnitzii , all of which are generally thought to be favorable in IBD [ 108 ]. Moreover, responders to EN had lower bacterial richness than those who did not respond [ 109 ].…”

Section: Therapeutic Indications For Specific Diets and Their Effect ...mentioning

confidence: 99%

Inflammatory Bowel Disease and Customized Nutritional Intervention Focusing on Gut Microbiome Balance

et al. 2022

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Inflammatory bowel disease (IBD) represents a chronic relapsing–remitting condition affecting the gastrointestinal system. The specific triggering IBD elements remain unknown: genetic variability, environmental factors, and alterations in the host immune system seem to be involved. An unbalanced diet and subsequent gut dysbiosis are risk factors, too. This review focuses on the description of the impact of pro- and anti-inflammatory food components on IBD, the role of different selected regimes (such as Crohn’s Disease Exclusion Diet, Immunoglobulin Exclusion Diet, Specific Carbohydrate Diet, LOFFLEX Diet, Low FODMAPs Diet, Mediterranean Diet) in the IBD management, and their effects on the gut microbiota (GM) composition and balance. The purpose is to investigate the potential positive action on IBD inflammation, which is associated with the exclusion or addition of certain foods or nutrients, to more consciously customize the nutritional intervention, taking also into account GM fluctuations during both disease flare-up and remission.

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Section: Therapeutic Indications For Specific Diets and Their Effect ...mentioning

confidence: 99%

Inflammatory Bowel Disease and Customized Nutritional Intervention Focusing on Gut Microbiome Balance

et al. 2022

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“…Indeed, dramatic effects are observed, some of which are counterintuitive to our understanding of the impact of microbiota on CD pathogenesis. For example, EEN appears to reduce microbial diversity, lower SCFA concentrations (including butyrate), and reduce Faecalibacterium prausnitzii , which is usually considered beneficial in IBD [ 77 ]. In another study, responders to EEN showed lower bacterial richness than nonresponders [ 78 ].…”

Section: Diets With Proof Of Clinical Efficacy For Ibdmentioning

confidence: 99%

“…The diet was based on the composition of Modulen ® formula (Nestle ® , Vevey, Switzerland), but instead used “real” food that was prescribed and individualized according to patients’ food preferences. It omits gluten, lactose, and alcohol and matches other macronutrients, vitamins, minerals, and fibre [ 75 , 77 , 79 ].…”

Section: Diets Without Proven Clinical Efficacy For Ibdmentioning

confidence: 99%

Nutritional Therapies and Their Influence on the Intestinal Microbiome in Pediatric Inflammatory Bowel Disease

et al. 2021

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Inflammatory bowel disease (IBD) is a chronic, autoimmune disorder of the gastrointestinal tract with numerous genetic and environmental risk factors. Patients with Crohn’s disease (CD) or ulcerative colitis (UC) often demonstrate marked disruptions of their gut microbiome. The intestinal microbiota is strongly influenced by diet. The association between the increasing incidence of IBD worldwide and increased consumption of a westernized diet suggests host nutrition may influence the progression or treatment of IBD via the microbiome. Several nutritional therapies have been studied for the treatment of CD and UC. While their mechanisms of action are only partially understood, existing studies do suggest that diet-driven changes in microbial composition and function underlie the diverse mechanisms of nutritional therapy. Despite existing therapies for IBD focusing heavily on immune suppression, nutrition is an important treatment option due to its superior safety profile, potentially low cost, and benefits for growth and development. These benefits are increasingly important to patients. In this review, we will describe the clinical efficacy of the different nutritional therapies that have been described for the treatment of CD and UC. We will also describe the effects of each nutritional therapy on the gut microbiome and summarize the strength of the literature with recommendations for the practicing clinician.

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“…In this diet, a patient consumes a base of 25-60% caloric requirement by formula and eats either a restricted or unrestricted food-based diet for the remainder. While PEN is less restrictive than EEN and can be used in maintaining remission [37], it has been shown to be inferior to EEN in inducing remission, promoting mucosal healing and improving the quality of life of IBD patients [38].…”

Section: Dietary Therapymentioning

confidence: 99%

Making Decisions about Dietary Therapy in Inflammatory Bowel Disease

Solomon

Park

Picoraro

2020

Gastrointestinal Disorders

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Treatment for inflammatory bowel disease (IBD) deserves an informed shared decision-making process between patient and doctor. IBD spans a spectrum of phenotypes that impact each patient uniquely. While treatment has primarily consisted of medical or surgical therapy, dietary approaches have become increasingly relevant. A majority of patients with IBD use some form of dietary modification, and it is common for patients to do this without their physicians’ knowledge. Lack of medical supervision can lead to nutritional deficiencies and a worsening disease state. Some patients work with their medical team to pursue a well-defined exclusion diet as a primary therapy, such as the specific carbohydrate diet, exclusive enteral nutrition, or the Crohn’s disease exclusion diet. The motivations to use dietary therapy for IBD remain unclear and the effectiveness has not been definitively established for many approaches. It is necessary for medical providers to be knowledgeable and to foster open communication with their patients in order to ensure the highest likelihood of remission. This review provides an overview of dietary treatment options, the current knowledge about patient motivations for pursuing dietary therapy, and the roles of patient empowerment and patient activation. We outline areas of improvement for the decision-making process.

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Systematic review with meta-analysis of partial enteral nutrition for the maintenance of remission in Crohn’s disease

Cited by 14 publications

References 42 publications

Inflammatory Bowel Disease and Customized Nutritional Intervention Focusing on Gut Microbiome Balance

Inflammatory Bowel Disease and Customized Nutritional Intervention Focusing on Gut Microbiome Balance

Nutritional Therapies and Their Influence on the Intestinal Microbiome in Pediatric Inflammatory Bowel Disease

Making Decisions about Dietary Therapy in Inflammatory Bowel Disease

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