This review paper provide a comprehensive elaboration about the antibacterial properties of Garlic and its derivatives. The antibacterial qualities of garlic, which has long been used in many traditional healing methods and is recognized for its therapeutic qualities. The study explores the bioactive substances found in garlic, including allicin, which has been shown to have antibacterial qualities against a variety of infections. The usefulness of garlic extracts and its organic compounds in preventing bacterial development is examined in a number of investigations and experiments that are discussed in this stud. It assesses the ways that garlic inhibits the growth of biofilms, interferes with the integrity of bacterial cell membranes, and modifies bacterial gene expression in order to determine how effective garlic is against bacteria. Garlic has the potential to improve the effectiveness of currently available medications and lessen the threat of antibiotic resistance to the world's health. The study also emphasizes the need for additional investigation to clarify the ideal circumstances and dosages for combining garlic with antimicrobial medications. To sum up, this study offers insightful information about the potential use of garlic as a natural remedy to manage bacterial infections. The results acknowledge the need for more investigation and clinical testing, but they also point to garlic's potential value as a supplement or replacement for traditional antibacterial medications. This presents a promising path for the creation of new and efficient treatment approaches to combat bacterial infections.